(11 nodes) Growth factor receptor domain 4 network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSORLP00000043772	TNFR-Cys domain-containing protein. (288 aa)
	erbb3	Protein kinase domain-containing protein. (1411 aa)
	LOC101169984	Receptor protein-tyrosine kinase. (1191 aa)
	H2LJC9_ORYLA	Proprotein convertase subtilisin/kexin type 5a. (1036 aa)
	LOC101174230	Receptor protein-tyrosine kinase. (1292 aa)
	LOC101172978	Erb-b2 receptor tyrosine kinase 3b. (1376 aa)
	erbb4	Receptor protein-tyrosine kinase. (1375 aa)
	egfr	Receptor protein-tyrosine kinase. (1185 aa)
	pcsk6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (923 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (1878 aa)
	LOC101165379	Receptor protein-tyrosine kinase. (1494 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101165379	LOC101174230	ENSORLP00000031995	ENSORLP00000007172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.833
LOC101165379	erbb4	ENSORLP00000031995	ENSORLP00000020056	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.901
LOC101169984	LOC101174230	ENSORLP00000004470	ENSORLP00000007172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.914
LOC101169984	egfr	ENSORLP00000004470	ENSORLP00000022143	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.902
LOC101172978	LOC101174230	ENSORLP00000009628	ENSORLP00000007172	Erb-b2 receptor tyrosine kinase 3b.	Receptor protein-tyrosine kinase.	0.836
LOC101172978	erbb3	ENSORLP00000009628	ENSORLP00000001883	Erb-b2 receptor tyrosine kinase 3b.	Protein kinase domain-containing protein.	0.905
LOC101174230	LOC101165379	ENSORLP00000007172	ENSORLP00000031995	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.833
LOC101174230	LOC101169984	ENSORLP00000007172	ENSORLP00000004470	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.914
LOC101174230	LOC101172978	ENSORLP00000007172	ENSORLP00000009628	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3b.	0.836
LOC101174230	egfr	ENSORLP00000007172	ENSORLP00000022143	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.915
LOC101174230	erbb3	ENSORLP00000007172	ENSORLP00000001883	Receptor protein-tyrosine kinase.	Protein kinase domain-containing protein.	0.843
LOC101174230	erbb4	ENSORLP00000007172	ENSORLP00000020056	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.906
egfr	LOC101169984	ENSORLP00000022143	ENSORLP00000004470	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.902
egfr	LOC101174230	ENSORLP00000022143	ENSORLP00000007172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.915
erbb3	LOC101172978	ENSORLP00000001883	ENSORLP00000009628	Protein kinase domain-containing protein.	Erb-b2 receptor tyrosine kinase 3b.	0.905
erbb3	LOC101174230	ENSORLP00000001883	ENSORLP00000007172	Protein kinase domain-containing protein.	Receptor protein-tyrosine kinase.	0.843
erbb4	LOC101165379	ENSORLP00000020056	ENSORLP00000031995	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.901
erbb4	LOC101174230	ENSORLP00000020056	ENSORLP00000007172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.906