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fgf7 fgf7 fgf11 fgf11 LOC101165330 LOC101165330 amh amh INHBC INHBC LOC101161650 LOC101161650 fgf16 fgf16 LOC101168772 LOC101168772 LOC101164147 LOC101164147 bmp6 bmp6 LOC101162532 LOC101162532 bmp8a bmp8a gdf6 gdf6 gdnf gdnf LOC100144359 LOC100144359 LOC101160897 LOC101160897 LOC101165149 LOC101165149 bmp4 bmp4 LOC101173146 LOC101173146 LOC101171139 LOC101171139 gdf3 gdf3 bmp5 bmp5 bmp2 bmp2 hgf hgf LOC101155815 LOC101155815 nodal nodal LOC101167980 LOC101167980 bmp15 bmp15 LOC101157368 LOC101157368 pdgfa pdgfa vegfa vegfa LOC101174977 LOC101174977 mstn mstn bmp10 bmp10 FGF6 FGF6 fgf23 fgf23 LOC101173579 LOC101173579 lefty1 lefty1 tgfb3 tgfb3 NRTN NRTN PSPN PSPN gdf10 gdf10 LOC101163237 LOC101163237 fgf20b fgf20b pdgfb pdgfb bmp3 bmp3 ENSORLP00000027361 ENSORLP00000027361 LOC101166036 LOC101166036 gdf11 gdf11 LOC111946374 LOC111946374 LOC101156757 LOC101156757 bdnf bdnf LOC101170230 LOC101170230 LOC101161449 LOC101161449 pdgfc pdgfc ntf3 ntf3 vegfb vegfb fgf5 fgf5 LOC101162992 LOC101162992 fgf18 fgf18 LOC101164584 LOC101164584 LOC101155037 LOC101155037 inha inha vegfc vegfc FGF13 FGF13 Fgf1 Fgf1 INHBB INHBB LOC101157631 LOC101157631 fgf3 fgf3 fgf4 fgf4 fgf19 fgf19 gdf5 gdf5 LOC101171064 LOC101171064 LOC101163346 LOC101163346 LOC101173472 LOC101173472 fgf10 fgf10 LOC101157715 LOC101157715 LOC101158636 LOC101158636 gsdf gsdf fgf8 fgf8 LOC101170375 LOC101170375 ENSORLP00000045700 ENSORLP00000045700 LOC101174326 LOC101174326 LOC101162318 LOC101162318 FGF6-2 FGF6-2 FGF14 FGF14 LOC101166143 LOC101166143 fgf20a fgf20a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
fgf11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
LOC101165330Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
amhAnti-muellerian hormone. (496 aa)
INHBCInhibin beta B chain-like protein. (379 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC101168772PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (405 aa)
LOC101164147Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (198 aa)
bmp6Bone morphogenetic protein 6. (424 aa)
LOC101162532Southpaw. (413 aa)
bmp8aBone morphogenetic protein 8a. (454 aa)
gdf6Growth differentiation factor 6b. (409 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (265 aa)
LOC100144359TGF_BETA_2 domain-containing protein. (398 aa)
LOC101160897Bone morphogenetic protein 7a. (425 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
bmp4Bone morphogenetic protein 4. (441 aa)
LOC101173146Bone morphogenetic protein 7b. (427 aa)
LOC101171139Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
gdf3Growth differentiation factor 3. (376 aa)
bmp5Bone morphogenetic protein 5. (417 aa)
bmp2TGF_BETA_2 domain-containing protein. (413 aa)
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (712 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
nodalNodal-related 2. (381 aa)
LOC101167980TGF_BETA_2 domain-containing protein. (506 aa)
bmp15Bone morphogenetic protein 15. (444 aa)
LOC101157368Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (291 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC101174977Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
mstnTGF_BETA_2 domain-containing protein. (424 aa)
bmp10Bone morphogenetic protein 10. (488 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
LOC101173579Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
lefty1Left-right determination factor. (358 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
NRTNNeurturin. (212 aa)
PSPNPersephin. (112 aa)
gdf10Growth differentiation factor 10b. (426 aa)
LOC101163237Growth differentiation factor 2. (415 aa)
fgf20bFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
bmp3Bone morphogenetic protein 3. (473 aa)
ENSORLP00000027361Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
LOC101166036Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (402 aa)
gdf11Growth differentiation factor 11. (389 aa)
LOC111946374Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101156757Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (219 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (281 aa)
LOC101170230Inhibin subunit beta Aa. (457 aa)
LOC101161449PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (135 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (284 aa)
vegfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (237 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC101162992Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC101164584Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (352 aa)
vegfcPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (494 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
INHBBInhibin subunit beta B. (386 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
gdf5Growth differentiation factor 5. (567 aa)
LOC101171064Growth differentiation factor 6a. (437 aa)
LOC101163346Bone morphogenetic protein 16. (516 aa)
LOC101173472Glial cell derived neurotrophic factor b. (245 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
LOC101157715Bone morphogenetic protein 10, like. (441 aa)
LOC101158636Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (197 aa)
gsdfGonadal soma derived factor. (216 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
LOC101170375Anti-dorsalizing morphogenic protein. (437 aa)
ENSORLP00000045700TGF_BETA_2 domain-containing protein. (131 aa)
LOC101174326Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
LOC101162318TGF_BETA_2 domain-containing protein. (298 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
LOC101166143Growth differentiation factor 9. (435 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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