STRINGSTRING
GADL1 GADL1 LOC101155409 LOC101155409 hoga1 hoga1 apip apip H2L6E1_ORYLA H2L6E1_ORYLA olgc7 olgc7 olgc8 olgc8 aco2 aco2 olgc6 olgc6 hal hal npl npl LOC100049273 LOC100049273 aldoc aldoc aldoa aldoa LOC101165489 LOC101165489 olgc5 olgc5 csad csad LOC101171534 LOC101171534 mvd mvd olgc-r2 olgc-r2 hacd2 hacd2 gucy1a2 gucy1a2 hacd1 hacd1 nthl1 nthl1 hacd4 hacd4 apex1 apex1 urod urod LOC101165720 LOC101165720 gad2 gad2 LOC101162414 LOC101162414 alad alad sgpl1 sgpl1 LOC101166627 LOC101166627 LOC101158999 LOC101158999 olgc-r1 olgc-r1 LOC101159207 LOC101159207 GLO1 GLO1 LOC101163149 LOC101163149 amd1 amd1 LOC101167167 LOC101167167 gad1 gad1 olgc3 olgc3 naxd naxd acmsd acmsd cyp17 cyp17 H2MYT6_ORYLA H2MYT6_ORYLA fabp2 fabp2 pisd pisd olgc2 olgc2 LOC101167828 LOC101167828 adcy7 adcy7 ADCY3 ADCY3 LOC101166500 LOC101166500 LOC101163920 LOC101163920 npr2 npr2 adcy6 adcy6 tsen2 tsen2 adsl adsl LOC101169035 LOC101169035 adcy8 adcy8 ddc ddc chac2 chac2 chac1 chac1 hacd3 hacd3 LOC101169827 LOC101169827 olgc9 olgc9 adcy5 adcy5 fech fech LOC101168897 LOC101168897 ENSORLP00000043517 ENSORLP00000043517 ENSORLP00000043520 ENSORLP00000043520 LOC101172459 LOC101172459
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GADL1Glutamate decarboxylase like 1. (519 aa)
LOC101155409Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (358 aa)
hoga14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (302 aa)
apipMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (245 aa)
H2L6E1_ORYLAGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (364 aa)
olgc7Guanylate cyclase. (1055 aa)
olgc8Guanylate cyclase. (859 aa)
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
olgc6Guanylate cyclase. (1075 aa)
halHistidine ammonia-lyase; Belongs to the PAL/histidase family. (654 aa)
nplN-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (341 aa)
LOC100049273Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
aldocFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (455 aa)
aldoaFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
LOC101165489Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (248 aa)
olgc5Guanylate cyclase. (1151 aa)
csadCysteine sulfinic acid decarboxylase. (508 aa)
LOC101171534Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (608 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (396 aa)
olgc-r2Guanylate cyclase. (1127 aa)
hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (244 aa)
gucy1a2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (806 aa)
hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (290 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (352 aa)
hacd4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (176 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (311 aa)
urodUroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (368 aa)
LOC101165720Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1110 aa)
gad2Glutamate decarboxylase 2. (586 aa)
LOC101162414Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1011 aa)
aladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (363 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (565 aa)
LOC101166627DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (553 aa)
LOC101158999Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (586 aa)
olgc-r1Guanylate cyclase. (1100 aa)
LOC101159207Adenylate cyclase 2b (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (851 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (179 aa)
LOC101163149Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1453 aa)
amd1S-adenosylmethionine decarboxylase proenzyme. (339 aa)
LOC101167167Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
gad1Glutamate decarboxylase 1a. (596 aa)
olgc3Guanylate cyclase. (1056 aa)
naxdATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (533 aa)
acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
cyp17Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family. (595 aa)
H2MYT6_ORYLASi:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (180 aa)
fabp2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (570 aa)
pisdPhosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (385 aa)
olgc2Guanylate cyclase. (1063 aa)
LOC101167828Uncharacterized protein. (1293 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1099 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
LOC101166500Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
LOC101163920Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (381 aa)
npr2Guanylate cyclase. (1055 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
tsen2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (401 aa)
adslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)
LOC101169035Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1231 aa)
ddcUncharacterized protein. (484 aa)
chac2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (214 aa)
chac1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (199 aa)
hacd3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (369 aa)
LOC101169827Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (200 aa)
olgc9Guanylate cyclase. (1075 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1196 aa)
fechFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (405 aa)
LOC101168897Uncharacterized protein. (583 aa)
ENSORLP00000043517Guanylate cyclase. (969 aa)
ENSORLP00000043520Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (543 aa)
LOC101172459Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1203 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.