24 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rfc4	Replication factor C (activator 1) 4. (355 aa)
	rfc2	Replication factor C (activator 1) 2. (355 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (2967 aa)
	rpa2	Replication protein A2. (280 aa)
	rev1	REV1 DNA directed polymerase. (1375 aa)
	ubc	Ubiquitin B. (782 aa)
	H2M970_ORYLA	Ubiquitin-like domain-containing protein. (129 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	LOC101166554	ATPase family AAA domain containing 5a. (1758 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC101165789	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (589 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa)
	meiob	Methionine sulfoxide reductase B1b. (462 aa)
	rpa3	Replication protein A3. (122 aa)
	LOC101172133	ATPase family AAA domain containing 5b. (959 aa)
	rfc1	Replication factor C subunit 1. (1152 aa)
	ENSORLP00000044710	annotation not available (829 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
	rps27a	Ribosomal protein S27a. (195 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000044710	LOC101166554	ENSORLP00000044710	ENSORLP00000012809	annotation not available	ATPase family AAA domain containing 5a.	0.640
ENSORLP00000044710	LOC101172133	ENSORLP00000044710	ENSORLP00000038541	annotation not available	ATPase family AAA domain containing 5b.	0.640
ENSORLP00000044710	pcna	ENSORLP00000044710	ENSORLP00000037447	annotation not available	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.877
ENSORLP00000044710	rev1	ENSORLP00000044710	ENSORLP00000015289	annotation not available	REV1 DNA directed polymerase.	0.535
ENSORLP00000044710	rev3l	ENSORLP00000044710	ENSORLP00000018995	annotation not available	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.661
ENSORLP00000044710	rfc1	ENSORLP00000044710	ENSORLP00000044312	annotation not available	Replication factor C subunit 1.	0.640
ENSORLP00000044710	rfc2	ENSORLP00000044710	ENSORLP00000023491	annotation not available	Replication factor C (activator 1) 2.	0.722
ENSORLP00000044710	rfc3	ENSORLP00000044710	ENSORLP00000004622	annotation not available	Replication factor C (activator 1) 3.	0.719
ENSORLP00000044710	rfc4	ENSORLP00000044710	ENSORLP00000026004	annotation not available	Replication factor C (activator 1) 4.	0.748
ENSORLP00000044710	rfc5	ENSORLP00000044710	ENSORLP00000035079	annotation not available	Replication factor C (activator 1) 5.	0.704
ENSORLP00000044710	rpa2	ENSORLP00000044710	ENSORLP00000017942	annotation not available	Replication protein A2.	0.836
ENSORLP00000044710	rpa3	ENSORLP00000044710	ENSORLP00000038347	annotation not available	Replication protein A3.	0.920
ENSORLP00000044710	rps27a	ENSORLP00000044710	ENSORLP00000038189	annotation not available	Ribosomal protein S27a.	0.485
H2M970_ORYLA	pcna	ENSORLP00000015051	ENSORLP00000037447	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.911
H2M970_ORYLA	rev1	ENSORLP00000015051	ENSORLP00000015289	Ubiquitin-like domain-containing protein.	REV1 DNA directed polymerase.	0.876
H2M970_ORYLA	rev3l	ENSORLP00000015051	ENSORLP00000018995	Ubiquitin-like domain-containing protein.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.616
H2M970_ORYLA	rpa2	ENSORLP00000015051	ENSORLP00000017942	Ubiquitin-like domain-containing protein.	Replication protein A2.	0.640
H2M970_ORYLA	rps27a	ENSORLP00000015051	ENSORLP00000038189	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.992
H2M970_ORYLA	uba52	ENSORLP00000015051	ENSORLP00000010731	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.552
H2M970_ORYLA	ubc	ENSORLP00000015051	ENSORLP00000015065	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.960