78 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2M2M7_ORYLA	B30.2/SPRY domain-containing protein. (345 aa)
	polk	Polymerase (DNA directed) kappa. (871 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (814 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1100 aa)
	LOC111949089	Uncharacterized protein. (552 aa)
	LOC101161097	USP domain-containing protein; Belongs to the peptidase C19 family. (1301 aa)
	H2LQ56_ORYLA	Uncharacterized protein. (510 aa)
	polh	Polymerase (DNA directed), eta. (708 aa)
	H2LQ44_ORYLA	Uncharacterized protein. (725 aa)
	H2LPD9_ORYLA	B box-type domain-containing protein. (263 aa)
	H2LPD5_ORYLA	Uncharacterized protein. (475 aa)
	LOC101160588	Uncharacterized protein. (578 aa)
	H2LMZ4_ORYLA	Uncharacterized protein. (469 aa)
	H2LMX6_ORYLA	B30.2/SPRY domain-containing protein. (191 aa)
	LOC101165789	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (589 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
	H2LGN3_ORYLA	Uncharacterized protein. (385 aa)
	LOC101163112	Uncharacterized protein. (550 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa)
	usp43	Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1216 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	rfc4	Replication factor C (activator 1) 4. (355 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	LOC101162809	Bloodthirsty-related gene family, member 1. (568 aa)
	ENSORLP00000028870	UmuC domain-containing protein. (136 aa)
	pold4	Si:dkey-28b4.7. (108 aa)
	LOC105357445	Uncharacterized protein. (609 aa)
	ENSORLP00000030517	CHY-type domain-containing protein. (216 aa)
	ENSORLP00000031558	RING-type domain-containing protein. (93 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (882 aa)
	ENSORLP00000033513	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (398 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	usp31	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1287 aa)
	LOC101163852	Bloodthirsty-related gene family, member 12. (579 aa)
	ENSORLP00000035840	IGv domain-containing protein. (150 aa)
	ENSORLP00000036422	Uncharacterized protein. (420 aa)
	ENSORLP00000036738	Si:dkey-46i9.6. (551 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
	LOC101155518	Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family. (1216 aa)
	rps27a	Ribosomal protein S27a. (195 aa)
	rpa3	Replication protein A3. (122 aa)
	LOC101172133	ATPase family AAA domain containing 5b. (959 aa)
	rchy1	Ring finger and CHY zinc finger domain containing 1. (261 aa)
	ENSORLP00000040540	Uncharacterized protein. (237 aa)
	rfc1	Replication factor C subunit 1. (1152 aa)
	ENSORLP00000044710	annotation not available (829 aa)
	ENSORLP00000044835	RING-type domain-containing protein. (105 aa)
	LOC101161603	Uncharacterized protein. (616 aa)
	ENSORLP00000045588	Uncharacterized protein. (562 aa)
	pole3	CBFD_NFYB_HMF domain-containing protein. (148 aa)
	meiob	Methionine sulfoxide reductase B1b. (462 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (752 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (310 aa)
	rfc2	Replication factor C (activator 1) 2. (355 aa)
	LOC101175289	Uncharacterized protein. (649 aa)
	LOC105356282	Uncharacterized protein. (567 aa)
	LOC101158889	FinTRIM family, member 67. (482 aa)
	sprtn	SprT-like N-terminal domain. (462 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (124 aa)
	LOC101161792	SCY domain-containing protein. (126 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (2967 aa)
	pclaf	PCNA clamp associated factor. (117 aa)
	rpa2	Replication protein A2. (280 aa)
	LOC101161952	Uncharacterized protein. (570 aa)
	LOC101171793	Uncharacterized protein. (558 aa)
	nploc4	NPL4 homolog, ubiquitin recognition factor. (624 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (524 aa)
	rev1	REV1 DNA directed polymerase. (1375 aa)
	LOC101172838	FinTRIM family, member 82. (573 aa)
	ubc	Ubiquitin B. (782 aa)
	H2M970_ORYLA	Ubiquitin-like domain-containing protein. (129 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	pold1	DNA polymerase. (1107 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	LOC101166554	ATPase family AAA domain containing 5a. (1758 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000028870	ENSORLP00000030517	ENSORLP00000028870	ENSORLP00000030517	UmuC domain-containing protein.	CHY-type domain-containing protein.	0.708
ENSORLP00000028870	ENSORLP00000033513	ENSORLP00000028870	ENSORLP00000033513	UmuC domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.791
ENSORLP00000028870	ENSORLP00000044710	ENSORLP00000028870	ENSORLP00000044710	UmuC domain-containing protein.	annotation not available	0.463
ENSORLP00000028870	H2M970_ORYLA	ENSORLP00000028870	ENSORLP00000015051	UmuC domain-containing protein.	Ubiquitin-like domain-containing protein.	0.861
ENSORLP00000028870	LOC101155518	ENSORLP00000028870	ENSORLP00000037945	UmuC domain-containing protein.	Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family.	0.456
ENSORLP00000028870	LOC101161097	ENSORLP00000028870	ENSORLP00000008873	UmuC domain-containing protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.456
ENSORLP00000028870	LOC101161792	ENSORLP00000028870	ENSORLP00000021359	UmuC domain-containing protein.	SCY domain-containing protein.	0.541
ENSORLP00000028870	LOC101166554	ENSORLP00000028870	ENSORLP00000012809	UmuC domain-containing protein.	ATPase family AAA domain containing 5a.	0.580
ENSORLP00000028870	LOC101172133	ENSORLP00000028870	ENSORLP00000038541	UmuC domain-containing protein.	ATPase family AAA domain containing 5b.	0.580
ENSORLP00000028870	POLE	ENSORLP00000028870	ENSORLP00000009820	UmuC domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.791
ENSORLP00000028870	RPA1	ENSORLP00000028870	ENSORLP00000004185	UmuC domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.541
ENSORLP00000028870	meiob	ENSORLP00000028870	ENSORLP00000003887	UmuC domain-containing protein.	Methionine sulfoxide reductase B1b.	0.463
ENSORLP00000028870	nploc4	ENSORLP00000028870	ENSORLP00000017276	UmuC domain-containing protein.	NPL4 homolog, ubiquitin recognition factor.	0.550
ENSORLP00000028870	pcna	ENSORLP00000028870	ENSORLP00000037447	UmuC domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.975
ENSORLP00000028870	pold1	ENSORLP00000028870	ENSORLP00000014232	UmuC domain-containing protein.	DNA polymerase.	0.846
ENSORLP00000028870	pold2	ENSORLP00000028870	ENSORLP00000016022	UmuC domain-containing protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.737
ENSORLP00000028870	pold4	ENSORLP00000028870	ENSORLP00000028941	UmuC domain-containing protein.	Si:dkey-28b4.7.	0.509
ENSORLP00000028870	pole2	ENSORLP00000028870	ENSORLP00000016116	UmuC domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.600
ENSORLP00000028870	pole3	ENSORLP00000028870	ENSORLP00000000708	UmuC domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.618
ENSORLP00000028870	pole4	ENSORLP00000028870	ENSORLP00000021366	UmuC domain-containing protein.	Polymerase (DNA-directed), epsilon 4, accessory subunit.	0.541