STRINGSTRING
LOC101163116 LOC101163116 erbb3 erbb3 LOC101166137 LOC101166137 yap1 yap1 NCSTN NCSTN LOC101158081 LOC101158081 LOC101163082 LOC101163082 wwp1 wwp1 mxd4 mxd4 psenen psenen SRC SRC LOC101172978 LOC101172978 ADAP1 ADAP1 LOC101171182 LOC101171182 uba52 uba52 PIK3CA PIK3CA LOC101168152 LOC101168152 shc1 shc1 LOC101166303 LOC101166303 hras hras fndc3b fndc3b H2M970_ORYLA H2M970_ORYLA ubc ubc grb2 grb2 erbb4 erbb4 LOC101159650 LOC101159650 psen2 psen2 wwox wwox SHC4 SHC4 LOC101159516 LOC101159516 LOC101154954 LOC101154954 kras kras LOC101165379 LOC101165379 Nedd4 Nedd4 LOC105355769 LOC105355769 egf egf LOC101160461 LOC101160461 CSDE1 CSDE1 LOC101164480 LOC101164480 LOC101174746 LOC101174746 LOC101155207 LOC101155207 LOC101154844 LOC101154844 rps27a rps27a LOC101164582 LOC101164582 ENSORLP00000040294 ENSORLP00000040294 fndc3a fndc3a LOC101155162 LOC101155162 ENSORLP00000041845 ENSORLP00000041845 LOC101168657 LOC101168657 esr1 esr1 LOC101167949 LOC101167949
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101163116Neuregulin 3b. (763 aa)
erbb3Protein kinase domain-containing protein. (1411 aa)
LOC101166137EGF-like domain-containing protein. (154 aa)
yap1Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)
NCSTNNicastrin. (677 aa)
LOC101158081Uncharacterized protein. (380 aa)
LOC101163082Signal transducer and activator of transcription. (786 aa)
wwp1WW domain containing E3 ubiquitin protein ligase 1. (960 aa)
mxd4MAX dimerization protein 4. (217 aa)
psenenPresenilin enhancer, gamma-secretase subunit. (101 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101172978Erb-b2 receptor tyrosine kinase 3b. (1376 aa)
ADAP1ArfGAP with dual PH domains 1. (377 aa)
LOC101171182Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (449 aa)
LOC101166303ArfGAP with dual PH domains 2. (378 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
ubcUbiquitin B. (782 aa)
grb2Growth factor receptor-bound protein 2b. (218 aa)
erbb4Receptor protein-tyrosine kinase. (1375 aa)
LOC101159650APH1B gamma secretase subunit. (258 aa)
psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (421 aa)
wwoxWW domain containing oxidoreductase. (429 aa)
SHC4SHC adaptor protein 4. (534 aa)
LOC101159516Neuregulin 2b. (712 aa)
LOC101154954Zgc:55558. (189 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
LOC101165379Receptor protein-tyrosine kinase. (1494 aa)
Nedd4Uncharacterized protein. (403 aa)
LOC105355769EGF-like domain-containing protein. (520 aa)
egfEpidermal growth factor. (966 aa)
LOC101160461EGF-like domain-containing protein. (607 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (875 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
LOC101174746E3 ubiquitin-protein ligase. (877 aa)
LOC101155207Betacellulin, epidermal growth factor family member. (183 aa)
LOC101154844Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (410 aa)
rps27aRibosomal protein S27a. (195 aa)
LOC101164582Neuregulin 2a. (711 aa)
ENSORLP00000040294Stathmin; Belongs to the stathmin family. (125 aa)
fndc3aFibronectin type III domain containing 3A. (1244 aa)
LOC101155162Uncharacterized protein. (373 aa)
ENSORLP00000041845HECT domain-containing protein. (106 aa)
LOC101168657Signal transducer and activator of transcription. (785 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
LOC101167949E3 ubiquitin-protein ligase. (879 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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