20 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSORLP00000040294	Stathmin; Belongs to the stathmin family. (125 aa)
	yap1	Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)
	NCSTN	Nicastrin. (677 aa)
	LOC101158081	Uncharacterized protein. (380 aa)
	LOC101163082	Signal transducer and activator of transcription. (786 aa)
	mxd4	MAX dimerization protein 4. (217 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	ADAP1	ArfGAP with dual PH domains 1. (377 aa)
	LOC101166303	ArfGAP with dual PH domains 2. (378 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	LOC101159650	APH1B gamma secretase subunit. (258 aa)
	psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (421 aa)
	wwox	WW domain containing oxidoreductase. (429 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)
	LOC101155162	Uncharacterized protein. (373 aa)
	LOC101168657	Signal transducer and activator of transcription. (785 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
	LOC101154844	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (410 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101154844	LOC101159650	ENSORLP00000044855	ENSORLP00000023040	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	APH1B gamma secretase subunit.	0.969
LOC101154844	NCSTN	ENSORLP00000044855	ENSORLP00000003658	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Nicastrin.	0.968
LOC101154844	psen2	ENSORLP00000044855	ENSORLP00000025023	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.449
LOC101154844	psenen	ENSORLP00000044855	ENSORLP00000008089	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin enhancer, gamma-secretase subunit.	0.975
LOC101159650	LOC101154844	ENSORLP00000023040	ENSORLP00000044855	APH1B gamma secretase subunit.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.969
LOC101159650	NCSTN	ENSORLP00000023040	ENSORLP00000003658	APH1B gamma secretase subunit.	Nicastrin.	0.984
LOC101159650	psen2	ENSORLP00000023040	ENSORLP00000025023	APH1B gamma secretase subunit.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.993
LOC101159650	psenen	ENSORLP00000023040	ENSORLP00000008089	APH1B gamma secretase subunit.	Presenilin enhancer, gamma-secretase subunit.	0.996
LOC101163082	LOC101164480	ENSORLP00000004950	ENSORLP00000036233	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.439
LOC101163082	LOC101168657	ENSORLP00000004950	ENSORLP00000042257	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC101163082	SRC	ENSORLP00000004950	ENSORLP00000008431	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.437
LOC101164480	LOC101163082	ENSORLP00000036233	ENSORLP00000004950	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.439
LOC101164480	LOC101168657	ENSORLP00000036233	ENSORLP00000042257	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.439
LOC101164480	SRC	ENSORLP00000036233	ENSORLP00000008431	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.900
LOC101164480	esr1	ENSORLP00000036233	ENSORLP00000042539	Tyrosine-protein kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.560
LOC101168657	LOC101163082	ENSORLP00000042257	ENSORLP00000004950	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC101168657	LOC101164480	ENSORLP00000042257	ENSORLP00000036233	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.439
LOC101168657	SRC	ENSORLP00000042257	ENSORLP00000008431	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.437
NCSTN	LOC101154844	ENSORLP00000003658	ENSORLP00000044855	Nicastrin.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.968
NCSTN	LOC101159650	ENSORLP00000003658	ENSORLP00000023040	Nicastrin.	APH1B gamma secretase subunit.	0.984