19 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sh2b3	SH2B adaptor protein 3. (724 aa)
	LOC101164953	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (954 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (946 aa)
	YES1	Tyrosine-protein kinase. (550 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	LOC101167902	Tyrosine-protein kinase. (511 aa)
	LOC101163758	Uncharacterized protein. (852 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	LOC101162321	Tyrosine-protein kinase. (547 aa)
	Kitlg	Kit ligand a. (233 aa)
	kit	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (994 aa)
	LOC101157019	Tyrosine-protein kinase. (537 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	lck	Tyrosine-protein kinase. (498 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)
	LOC101167011	Tyrosine-protein kinase. (526 aa)
	LOC101158476	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (557 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kitlg	LOC101164953	ENSORLP00000028341	ENSORLP00000005520	Kit ligand a.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.993
Kitlg	grb2	ENSORLP00000028341	ENSORLP00000019097	Kit ligand a.	Growth factor receptor-bound protein 2b.	0.552
Kitlg	kit	ENSORLP00000028341	ENSORLP00000029524	Kit ligand a.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.992
Kitlg	ptpn6	ENSORLP00000028341	ENSORLP00000015555	Kit ligand a.	Protein tyrosine phosphatase non-receptor type 6.	0.537
Kitlg	sh2b3	ENSORLP00000028341	ENSORLP00000004446	Kit ligand a.	SH2B adaptor protein 3.	0.652
LOC101157019	LOC101158476	ENSORLP00000029844	ENSORLP00000044381	Tyrosine-protein kinase.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.577
LOC101157019	LOC101162321	ENSORLP00000029844	ENSORLP00000022375	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.940
LOC101157019	LOC101163758	ENSORLP00000029844	ENSORLP00000018205	Tyrosine-protein kinase.	Uncharacterized protein.	0.577
LOC101157019	LOC101164480	ENSORLP00000029844	ENSORLP00000036233	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.435
LOC101157019	LOC101167011	ENSORLP00000029844	ENSORLP00000041511	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC101157019	LOC101167902	ENSORLP00000029844	ENSORLP00000015921	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.440
LOC101157019	SRC	ENSORLP00000029844	ENSORLP00000008431	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.435
LOC101157019	YES1	ENSORLP00000029844	ENSORLP00000014039	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.940
LOC101157019	cbl	ENSORLP00000029844	ENSORLP00000009540	Tyrosine-protein kinase.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.577
LOC101157019	grb2	ENSORLP00000029844	ENSORLP00000019097	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.630
LOC101157019	lck	ENSORLP00000029844	ENSORLP00000039217	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.440
LOC101157019	ptpn6	ENSORLP00000029844	ENSORLP00000015555	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.500
LOC101158476	LOC101157019	ENSORLP00000044381	ENSORLP00000029844	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	Tyrosine-protein kinase.	0.577
LOC101158476	LOC101162321	ENSORLP00000044381	ENSORLP00000022375	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	Tyrosine-protein kinase.	0.491
LOC101158476	LOC101164480	ENSORLP00000044381	ENSORLP00000036233	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	Tyrosine-protein kinase.	0.501