STRINGSTRING
cdk1 cdk1 LOC101158678 LOC101158678 psmf1 psmf1 psmc4 psmc4 LOC110016721 LOC110016721 LOC101156678 LOC101156678 psma5 psma5 anapc7 anapc7 psmc1 psmc1 LOC101160375 LOC101160375 psmc6 psmc6 FZR1 FZR1 anapc5 anapc5 ccnb1 ccnb1 psme2 psme2 skp2 skp2 nek2 nek2 ubc ubc H2M970_ORYLA H2M970_ORYLA ube2s ube2s cdc16 cdc16 psmb1 psmb1 psmc3 psmc3 kxd1 kxd1 psmd7 psmd7 psma3 psma3 LOC101174862 LOC101174862 H2M2L4_ORYLA H2M2L4_ORYLA psmb2 psmb2 tm7sf3 tm7sf3 bub3 bub3 LOC101173089 LOC101173089 psmd2 psmd2 ube2c ube2c anapc16 anapc16 LOC101155046 LOC101155046 uba52 uba52 psmd6 psmd6 LOC101154878 LOC101154878 psmd1 psmd1 psmb9-like psmb9-like psmb9 psmb9 psme1 psme1 psma2 psma2 psmd9 psmd9 aurka aurka psmc5 psmc5 psmd5 psmd5 anapc1 anapc1 psmd14 psmd14 ccna1 ccna1 cul1 cul1 anapc10 anapc10 Rgs22 Rgs22 FBXO43 FBXO43 psmd8 psmd8 bicra bicra psma4 psma4 psmb4 psmb4 psma1 psma1 anapc2 anapc2 pttg1 pttg1 skp1 skp1 aurkb aurkb anapc4 anapc4 LOC101157953 LOC101157953 psmd13 psmd13 psmb8 psmb8 Cdc27 Cdc27 LOC101162259 LOC101162259 psmd3 psmd3 anapc15 anapc15 bicral bicral LOC101174707 LOC101174707 fam89a fam89a ENSORLP00000038704 ENSORLP00000038704 psmb7 psmb7 rps27a rps27a LOC111949049 LOC111949049 rb1 rb1 bub1b bub1b psmb3 psmb3 psme4 psme4 psma8 psma8 psmd10 psmd10 ENSORLP00000033350 ENSORLP00000033350 ENSORLP00000033333 ENSORLP00000033333 psmd12 psmd12 anapc11 anapc11 cdc20b cdc20b fbxo5 fbxo5 cdc20 cdc20 psmc2 psmc2 ENSORLP00000028480 ENSORLP00000028480 cdk2 cdk2 LOC111948194 LOC111948194 psme3 psme3 cdc23 cdc23 mad2l1 mad2l1 ccna2 ccna2 LOC101174330 LOC101174330
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdk1Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II. Catalytic component of MPF (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (303 aa)
LOC101158678Proteasome subunit beta. (278 aa)
psmf1Uncharacterized protein. (271 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
LOC110016721Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LOC101156678UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
psma5Proteasome subunit alpha type. (241 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (443 aa)
LOC101160375Uncharacterized protein. (544 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (498 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
ccnb1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (404 aa)
psme2Proteasome activator subunit 2. (241 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (421 aa)
nek2NIMA-related kinase 2. (442 aa)
ubcUbiquitin B. (782 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (226 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
psmb1Proteasome subunit beta. (237 aa)
psmc3Proteasome 26S subunit ATPase 3; Belongs to the AAA ATPase family. (427 aa)
kxd1KxDL motif containing 1. (184 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (324 aa)
psma3Proteasome subunit alpha type. (255 aa)
LOC101174862Fizzy/cell division cycle 20 related 1b. (492 aa)
H2M2L4_ORYLABLM10_mid domain-containing protein. (567 aa)
psmb2Proteasome subunit beta. (199 aa)
tm7sf3Transmembrane 7 superfamily member 3. (565 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
LOC101173089Proteasome 26S subunit, non-ATPase 4b. (376 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
anapc16Anaphase promoting complex subunit 16. (83 aa)
LOC101155046Proteasome subunit alpha type. (246 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
LOC101154878Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (191 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
psmb9-likeProteasome subunit, beta type 9-like. (217 aa)
psmb9Proteasome subunit beta type-9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity). (216 aa)
psme1Proteasome activator subunit 1. (250 aa)
psma2Proteasome subunit alpha type. (234 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (439 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (524 aa)
anapc1Anaphase promoting complex subunit 1. (1673 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (325 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (413 aa)
cul1Cullin 1b; Belongs to the cullin family. (801 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
Rgs22RGS domain-containing protein. (341 aa)
FBXO43F-box protein 43. (588 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1712 aa)
psma4Proteasome subunit alpha type. (261 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psma1Proteasome endopeptidase complex. (238 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (802 aa)
pttg1Uncharacterized protein. (181 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
aurkbProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
LOC101157953Proteasome 26S subunit, non-ATPase 4a. (372 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psmb8Proteasome subunit beta. (275 aa)
Cdc27Cell division cycle 27. (382 aa)
LOC101162259Proteasome endopeptidase complex. (320 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (516 aa)
anapc15Anaphase promoting complex subunit 15. (137 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (787 aa)
LOC101174707Proteasome 26S subunit, non-ATPase 11b. (422 aa)
fam89aFamily with sequence similarity 89 member A. (171 aa)
ENSORLP00000038704DUF3437 domain-containing protein. (311 aa)
psmb7Proteasome subunit beta. (286 aa)
rps27aRibosomal protein S27a. (195 aa)
LOC111949049Proteasome subunit beta. (276 aa)
rb1Retinoblastoma 1. (916 aa)
bub1bBUB1 N-terminal domain-containing protein. (564 aa)
psmb3Proteasome subunit beta 3. (223 aa)
psme4Proteasome activator subunit 4a. (1848 aa)
psma8Proteasome subunit alpha type. (251 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSORLP00000033350Uncharacterized protein. (150 aa)
ENSORLP00000033333Proteasome subunit beta. (293 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (457 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
cdc20bWD_REPEATS_REGION domain-containing protein. (475 aa)
fbxo5F-box protein 5. (367 aa)
cdc20WD_REPEATS_REGION domain-containing protein. (501 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
ENSORLP00000028480Uncharacterized protein. (144 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC111948194Proteasome subunit beta. (275 aa)
psme3Proteasome activator subunit 3. (256 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (559 aa)
mad2l1HORMA domain-containing protein. (206 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (429 aa)
LOC101174330PCI domain-containing protein. (468 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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