34 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (544 aa)
	pdgfa	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)
	LOC101154761	Signal transducer and activator of transcription. (763 aa)
	LOC101163082	Signal transducer and activator of transcription. (786 aa)
	pdgfrb	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1112 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101168152	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	nedd9	Neural precursor cell expressed, developmentally down-regulated 9. (784 aa)
	cass4	Cas scaffold protein family member 4. (793 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	nck1	Cytoplasmic protein. (392 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1055 aa)
	LOC101171139	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	LOC101165149	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
	LOC101166170	Growth factor receptor bound protein 7. (562 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	rapgef1	Uncharacterized protein. (881 aa)
	bcar1	BCAR1 scaffold protein, Cas family member. (947 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
	LOC101154954	Zgc:55558. (189 aa)
	LOC101158464	Rap guanine nucleotide exchange factor (GEF) 1b. (1184 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	kras	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
	LOC110016423	Uncharacterized protein. (313 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (875 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	nck2	Cytoplasmic protein. (398 aa)
	LOC101162184	Signal transducer and activator of transcription. (723 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)
	LOC101168657	Signal transducer and activator of transcription. (785 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC101158464	ENSORLP00000034821	ENSORLP00000030168	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.414
CSDE1	LOC101164480	ENSORLP00000034821	ENSORLP00000036233	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.417
CSDE1	LOC101168152	ENSORLP00000034821	ENSORLP00000011212	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.530
CSDE1	PIK3CA	ENSORLP00000034821	ENSORLP00000011211	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.530
CSDE1	SRC	ENSORLP00000034821	ENSORLP00000008431	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.417
CSDE1	grb2	ENSORLP00000034821	ENSORLP00000019097	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.691
CSDE1	pdgfrb	ENSORLP00000034821	ENSORLP00000006025	Cold shock domain containing E1, RNA-binding.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.497
CSDE1	pik3cb	ENSORLP00000034821	ENSORLP00000034377	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.530
CSDE1	rapgef1	ENSORLP00000034821	ENSORLP00000020777	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.414
CSDE1	rasa1	ENSORLP00000034821	ENSORLP00000012485	Cold shock domain containing E1, RNA-binding.	RAS p21 protein activator (GTPase activating protein) 1a.	0.813
LOC101154761	LOC101162184	ENSORLP00000000200	ENSORLP00000039016	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.525
LOC101154761	LOC101163082	ENSORLP00000000200	ENSORLP00000004950	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.483
LOC101154761	LOC101164480	ENSORLP00000000200	ENSORLP00000036233	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.492
LOC101154761	LOC101168657	ENSORLP00000000200	ENSORLP00000042257	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.483
LOC101154761	SRC	ENSORLP00000000200	ENSORLP00000008431	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.492
LOC101154761	pdgfrb	ENSORLP00000000200	ENSORLP00000006025	Signal transducer and activator of transcription.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.537
LOC101154954	LOC101158464	ENSORLP00000030026	ENSORLP00000030168	Zgc:55558.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.414
LOC101154954	LOC101164480	ENSORLP00000030026	ENSORLP00000036233	Zgc:55558.	Tyrosine-protein kinase.	0.530
LOC101154954	LOC101168152	ENSORLP00000030026	ENSORLP00000011212	Zgc:55558.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.840
LOC101154954	PIK3CA	ENSORLP00000030026	ENSORLP00000011211	Zgc:55558.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.840