STRINGSTRING
LOC101156149 LOC101156149 map2k5 map2k5 LOC101158674 LOC101158674 LOC101162314 LOC101162314 LOC101175459 LOC101175459 nkpd1 nkpd1 ppp2ca ppp2ca dusp7 dusp7 map2k2 map2k2 H2LLS9_ORYLA H2LLS9_ORYLA SHC3 SHC3 LOC101174845 LOC101174845 LOC101164147 LOC101164147 ppp4r1 ppp4r1 ap2s1 ap2s1 map2k1 map2k1 LOC101167061 LOC101167061 JUND JUND LOC101157368 LOC101157368 LOC101166594 LOC101166594 PIK3CA PIK3CA LOC101168152 LOC101168152 LOC101175696 LOC101175696 crk crk egr3 egr3 crkl crkl hras hras LOC101175078 LOC101175078 LOC101159747 LOC101159747 H2M9H6_ORYLA H2M9H6_ORYLA LOC101160746 LOC101160746 srf srf LOC101159256 LOC101159256 ap2m1 ap2m1 LOC101171688 LOC101171688 LOC101169770 LOC101169770 egr2 egr2 MAPKAPK2 MAPKAPK2 fnbp4 fnbp4 ascl1 ascl1 rapgef1 rapgef1 LOC101165887 LOC101165887 ap2a1 ap2a1 irs2 irs2 LOC101155812 LOC101155812 LOC101173112 LOC101173112 H2MVE2_ORYLA H2MVE2_ORYLA LOC101164872 LOC101164872 H2MX42_ORYLA H2MX42_ORYLA dusp6 dusp6 ralgds ralgds clta clta id3 id3 LOC101160731 LOC101160731 LOC101155008 LOC101155008 ppp2cb ppp2cb LOC101169648 LOC101169648 nab1 nab1 chd4 chd4 LOC101157651 LOC101157651 LOC101165801 LOC101165801 egr1 egr1 LOC101154954 LOC101154954 LOC101158464 LOC101158464 LOC101157118 LOC101157118 LOC101164105 LOC101164105 fosl1 fosl1 vrk3 vrk3 LOC101167564 LOC101167564 ENSORLP00000031669 ENSORLP00000031669 LOC105358811 LOC105358811 kras kras LOC101173264 LOC101173264 LOC110016423 LOC110016423 pik3cb pik3cb LOC101174984 LOC101174984 CSDE1 CSDE1 LOC101162042 LOC101162042 ntf3 ntf3 relch relch LOC101162905 LOC101162905 LOC101172819 LOC101172819 LOC101160542 LOC101160542 shc2 shc2 mapk15 mapk15 LOC101167252 LOC101167252 LOC101164062 LOC101164062 dnal4 dnal4 frs2 frs2 LOC101163402 LOC101163402 trib2 trib2 LOC101157884 LOC101157884 LOC111949028 LOC111949028 SGK1 SGK1 LOC101174084 LOC101174084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101156149Uncharacterized protein. (201 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)
LOC101158674cAMP responsive element binding protein 1. (315 aa)
LOC101162314Inhibitor of DNA binding 4. (138 aa)
LOC101175459BHLH domain-containing protein. (457 aa)
nkpd1NTPase, KAP family P-loop domain containing 1. (686 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
dusp7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)
H2LLS9_ORYLASi:dkey-23i12.7. (111 aa)
SHC3SHC adaptor protein 3. (665 aa)
LOC101174845Chromodomain helicase DNA binding protein 4a. (1950 aa)
LOC101164147Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (198 aa)
ppp4r1WRNPLPNID domain-containing protein. (969 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
LOC101167061Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
JUNDBZIP domain-containing protein. (296 aa)
LOC101157368Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (291 aa)
LOC101166594Ribosomal protein S6 kinase. (807 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101175696Mitogen-activated protein kinase. (354 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
egr3Uncharacterized protein. (410 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC101175078Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (359 aa)
LOC101159747Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
H2M9H6_ORYLAAchaete-scute family bHLH transcription factor 1b. (185 aa)
LOC101160746Tribbles pseudokinase 1. (363 aa)
srfSerum response factor b. (611 aa)
LOC101159256Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
LOC101171688AP complex subunit beta. (953 aa)
LOC101169770JunB proto-oncogene, AP-1 transcription factor subunit a. (336 aa)
egr2Early growth response 2b. (449 aa)
MAPKAPK2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
fnbp4Formin binding protein 4. (843 aa)
ascl1Achaete-scute family bHLH transcription factor 1a. (178 aa)
rapgef1Uncharacterized protein. (881 aa)
LOC101165887ETS transcription factor ELK1. (571 aa)
ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (983 aa)
irs2Insulin receptor substrate 2b. (1081 aa)
LOC101155812ANK_REP_REGION domain-containing protein. (1684 aa)
LOC101173112Kinase D-interacting substrate 220b. (1713 aa)
H2MVE2_ORYLAProtein phosphatase 4, regulatory subunit 4. (726 aa)
LOC101164872AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (920 aa)
H2MX42_ORYLAZgc:171775. (273 aa)
dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
ralgdsRal guanine nucleotide dissociation stimulator. (774 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
id3Inhibitor of DNA binding 3. (118 aa)
LOC101160731Mitogen-activated protein kinase. (360 aa)
LOC101155008SH3 domain containing GRB2 like 2a, endophilin A1. (374 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC101169648Ribosomal protein S6 kinase. (748 aa)
nab1NGFI-A binding protein 1a (EGR1 binding protein 1). (507 aa)
chd4Uncharacterized protein. (1969 aa)
LOC101157651Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1127 aa)
LOC101165801NGFI-A binding protein 2 (EGR1 binding protein 2). (495 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (511 aa)
LOC101154954Zgc:55558. (189 aa)
LOC101158464Rap guanine nucleotide exchange factor (GEF) 1b. (1184 aa)
LOC101157118V-ral simian leukemia viral oncogene homolog Ba (ras related). (207 aa)
LOC101164105cAMP responsive element binding protein 1b. (329 aa)
fosl1FOS-like antigen 1a. (340 aa)
vrk3VRK serine/threonine kinase 3. (510 aa)
LOC101167564Ribosomal protein S6 kinase. (787 aa)
ENSORLP00000031669BZIP domain-containing protein. (91 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
LOC101173264Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (218 aa)
LOC110016423Uncharacterized protein. (313 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
LOC101174984Insulin receptor substrate 2a. (1049 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (875 aa)
LOC101162042Mitogen-activated protein kinase. (361 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (284 aa)
relchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1209 aa)
LOC101162905Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC101172819Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
LOC101160542Uncharacterized protein. (351 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (711 aa)
mapk15Mitogen-activated protein kinase. (603 aa)
LOC101167252V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
LOC101164062JunB proto-oncogene, AP-1 transcription factor subunit b. (327 aa)
dnal4Dynein light chain. (106 aa)
frs2Fibroblast growth factor receptor substrate 2b. (526 aa)
LOC101163402Ribosomal protein S6 kinase. (746 aa)
trib2Tribbles pseudokinase 2. (345 aa)
LOC101157884BZIP domain-containing protein. (177 aa)
LOC111949028BZIP domain-containing protein. (258 aa)
SGK1Non-specific serine/threonine protein kinase. (653 aa)
LOC101174084KID domain-containing protein. (205 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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