13 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kras	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
	LOC101154954	Zgc:55558. (189 aa)
	LOC101159516	Neuregulin 2b. (712 aa)
	LOC101163116	Neuregulin 3b. (763 aa)
	LOC101164582	Neuregulin 2a. (711 aa)
	LOC101155207	Betacellulin, epidermal growth factor family member. (183 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (875 aa)
	LOC101166137	EGF-like domain-containing protein. (154 aa)
	LOC101160461	EGF-like domain-containing protein. (607 aa)
	LOC105355769	EGF-like domain-containing protein. (520 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	LOC101174230	Receptor protein-tyrosine kinase. (1292 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC101155207	ENSORLP00000034821	ENSORLP00000037400	Cold shock domain containing E1, RNA-binding.	Betacellulin, epidermal growth factor family member.	0.425
CSDE1	LOC101166137	ENSORLP00000034821	ENSORLP00000002190	Cold shock domain containing E1, RNA-binding.	EGF-like domain-containing protein.	0.440
CSDE1	LOC101174230	ENSORLP00000034821	ENSORLP00000007172	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.516
CSDE1	grb2	ENSORLP00000034821	ENSORLP00000019097	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.691
LOC101154954	LOC101155207	ENSORLP00000030026	ENSORLP00000037400	Zgc:55558.	Betacellulin, epidermal growth factor family member.	0.425
LOC101154954	LOC101166137	ENSORLP00000030026	ENSORLP00000002190	Zgc:55558.	EGF-like domain-containing protein.	0.440
LOC101154954	LOC101174230	ENSORLP00000030026	ENSORLP00000007172	Zgc:55558.	Receptor protein-tyrosine kinase.	0.516
LOC101154954	grb2	ENSORLP00000030026	ENSORLP00000019097	Zgc:55558.	Growth factor receptor-bound protein 2b.	0.691
LOC101154954	hras	ENSORLP00000030026	ENSORLP00000014318	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.911
LOC101154954	kras	ENSORLP00000030026	ENSORLP00000031976	Zgc:55558.	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.	0.901
LOC101155207	CSDE1	ENSORLP00000037400	ENSORLP00000034821	Betacellulin, epidermal growth factor family member.	Cold shock domain containing E1, RNA-binding.	0.425
LOC101155207	LOC101154954	ENSORLP00000037400	ENSORLP00000030026	Betacellulin, epidermal growth factor family member.	Zgc:55558.	0.425
LOC101155207	LOC101159516	ENSORLP00000037400	ENSORLP00000029121	Betacellulin, epidermal growth factor family member.	Neuregulin 2b.	0.548
LOC101155207	LOC101160461	ENSORLP00000037400	ENSORLP00000034682	Betacellulin, epidermal growth factor family member.	EGF-like domain-containing protein.	0.548
LOC101155207	LOC101164582	ENSORLP00000037400	ENSORLP00000038210	Betacellulin, epidermal growth factor family member.	Neuregulin 2a.	0.548
LOC101155207	LOC101166137	ENSORLP00000037400	ENSORLP00000002190	Betacellulin, epidermal growth factor family member.	EGF-like domain-containing protein.	0.911
LOC101155207	LOC101174230	ENSORLP00000037400	ENSORLP00000007172	Betacellulin, epidermal growth factor family member.	Receptor protein-tyrosine kinase.	0.505
LOC101155207	grb2	ENSORLP00000037400	ENSORLP00000019097	Betacellulin, epidermal growth factor family member.	Growth factor receptor-bound protein 2b.	0.552
LOC101155207	hras	ENSORLP00000037400	ENSORLP00000014318	Betacellulin, epidermal growth factor family member.	HRas proto-oncogene, GTPase a.	0.425
LOC101155207	kras	ENSORLP00000037400	ENSORLP00000031976	Betacellulin, epidermal growth factor family member.	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.	0.425