18 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
	angptl7	Angiopoietin-like 7. (340 aa)
	LOC101154790	Angiopoietin 2b. (506 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101168152	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	angpt2	Angiopoietin 2a. (492 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (449 aa)
	angpt1	Angiopoietin 1. (530 aa)
	LOC101174926	Docking protein 2. (618 aa)
	tie1	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1133 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	LOC101166170	Growth factor receptor bound protein 7. (562 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	SHC4	SHC adaptor protein 4. (534 aa)
	LOC101171463	Angiopoietin 4. (516 aa)
	LOC101154954	Zgc:55558. (189 aa)
	kras	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (875 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC101168152	ENSORLP00000034821	ENSORLP00000011212	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.530
CSDE1	PIK3CA	ENSORLP00000034821	ENSORLP00000011211	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.530
CSDE1	SHC4	ENSORLP00000034821	ENSORLP00000027207	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.419
CSDE1	grb2	ENSORLP00000034821	ENSORLP00000019097	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.691
CSDE1	pik3cb	ENSORLP00000034821	ENSORLP00000034377	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.530
CSDE1	shc1	ENSORLP00000034821	ENSORLP00000012223	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.419
CSDE1	tie1	ENSORLP00000034821	ENSORLP00000013414	Cold shock domain containing E1, RNA-binding.	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.	0.471
LOC101154790	tie1	ENSORLP00000006800	ENSORLP00000013414	Angiopoietin 2b.	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.	0.913
LOC101154954	LOC101168152	ENSORLP00000030026	ENSORLP00000011212	Zgc:55558.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.840
LOC101154954	PIK3CA	ENSORLP00000030026	ENSORLP00000011211	Zgc:55558.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.840
LOC101154954	SHC4	ENSORLP00000030026	ENSORLP00000027207	Zgc:55558.	SHC adaptor protein 4.	0.419
LOC101154954	grb2	ENSORLP00000030026	ENSORLP00000019097	Zgc:55558.	Growth factor receptor-bound protein 2b.	0.691
LOC101154954	hras	ENSORLP00000030026	ENSORLP00000014318	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.911
LOC101154954	kras	ENSORLP00000030026	ENSORLP00000031976	Zgc:55558.	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.	0.901
LOC101154954	pik3cb	ENSORLP00000030026	ENSORLP00000034377	Zgc:55558.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.828
LOC101154954	shc1	ENSORLP00000030026	ENSORLP00000012223	Zgc:55558.	SHC (Src homology 2 domain containing) transforming protein 1.	0.419
LOC101154954	tie1	ENSORLP00000030026	ENSORLP00000013414	Zgc:55558.	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.	0.471
LOC101166170	LOC101168152	ENSORLP00000017682	ENSORLP00000011212	Growth factor receptor bound protein 7.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.430
LOC101166170	PIK3CA	ENSORLP00000017682	ENSORLP00000011211	Growth factor receptor bound protein 7.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.430
LOC101166170	SHC4	ENSORLP00000017682	ENSORLP00000027207	Growth factor receptor bound protein 7.	SHC adaptor protein 4.	0.434