35 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101159109	Mothers against decapentaplegic homolog. (467 aa)
	LOC101157196	Cyclin T2b; Belongs to the cyclin family. (562 aa)
	SMAD4	Mothers against decapentaplegic homolog. (510 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	cdk8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (463 aa)
	LOC100049240	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (814 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	men1	Multiple endocrine neoplasia I. (691 aa)
	smad2	Mothers against decapentaplegic homolog. (473 aa)
	LOC101159747	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
	H2M970_ORYLA	Ubiquitin-like domain-containing protein. (129 aa)
	ubc	Ubiquitin B. (782 aa)
	tfdp1	Transcription factor. (413 aa)
	LOC101169770	JunB proto-oncogene, AP-1 transcription factor subunit a. (336 aa)
	cdk19	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (484 aa)
	e2f4	E2F transcription factor 4. (390 aa)
	ccnt1	Cyclin T1; Belongs to the cyclin family. (251 aa)
	LOC101164754	E2F transcription factor 5. (354 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1112 aa)
	LOC101169523	Mothers against decapentaplegic homolog. (425 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (534 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (835 aa)
	LOC101173916	Mothers against decapentaplegic homolog. (538 aa)
	ccnc	Cyclin C; Belongs to the cyclin family. (283 aa)
	sp1	Sp1 transcription factor. (467 aa)
	rnf111	Ring finger protein 111. (1017 aa)
	rps27a	Ribosomal protein S27a. (195 aa)
	LOC101162905	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC101164062	JunB proto-oncogene, AP-1 transcription factor subunit b. (327 aa)
	ccnt2	Cyclin T2; Belongs to the cyclin family. (755 aa)
	smad7	Mothers against decapentaplegic homolog. (375 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (257 aa)
	LOC101163504	Mothers against decapentaplegic homolog. (528 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2M970_ORYLA	rnf111	ENSORLP00000015051	ENSORLP00000038000	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.719
H2M970_ORYLA	rps27a	ENSORLP00000015051	ENSORLP00000038189	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.992
H2M970_ORYLA	uba52	ENSORLP00000015051	ENSORLP00000010731	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.552
H2M970_ORYLA	ubc	ENSORLP00000015051	ENSORLP00000015065	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.960
LOC101157196	ccnc	ENSORLP00000005423	ENSORLP00000033442	Cyclin T2b; Belongs to the cyclin family.	Cyclin C; Belongs to the cyclin family.	0.652
LOC101157196	ccnk	ENSORLP00000005423	ENSORLP00000026551	Cyclin T2b; Belongs to the cyclin family.	Cyclin K; Belongs to the cyclin family.	0.835
LOC101157196	ccnt1	ENSORLP00000005423	ENSORLP00000020652	Cyclin T2b; Belongs to the cyclin family.	Cyclin T1; Belongs to the cyclin family.	0.568
LOC101157196	ccnt2	ENSORLP00000005423	ENSORLP00000043132	Cyclin T2b; Belongs to the cyclin family.	Cyclin T2; Belongs to the cyclin family.	0.554
LOC101157196	cdk19	ENSORLP00000005423	ENSORLP00000019102	Cyclin T2b; Belongs to the cyclin family.	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily.	0.560
LOC101157196	cdk8	ENSORLP00000005423	ENSORLP00000011144	Cyclin T2b; Belongs to the cyclin family.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.560
LOC101157196	cdk9	ENSORLP00000005423	ENSORLP00000022884	Cyclin T2b; Belongs to the cyclin family.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.954
LOC101157196	sp1	ENSORLP00000005423	ENSORLP00000034132	Cyclin T2b; Belongs to the cyclin family.	Sp1 transcription factor.	0.532
LOC101159109	LOC101159747	ENSORLP00000019646	ENSORLP00000015020	Mothers against decapentaplegic homolog.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.943
LOC101159109	LOC101162905	ENSORLP00000019646	ENSORLP00000039541	Mothers against decapentaplegic homolog.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.943
LOC101159109	LOC101163504	ENSORLP00000019646	ENSORLP00000045202	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.979
LOC101159109	LOC101164754	ENSORLP00000019646	ENSORLP00000022426	Mothers against decapentaplegic homolog.	E2F transcription factor 5.	0.487
LOC101159109	LOC101169523	ENSORLP00000019646	ENSORLP00000002748	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
LOC101159109	LOC101173916	ENSORLP00000019646	ENSORLP00000029700	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.979
LOC101159109	SMAD4	ENSORLP00000019646	ENSORLP00000006328	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.988
LOC101159109	cdk8	ENSORLP00000019646	ENSORLP00000011144	Mothers against decapentaplegic homolog.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.445