46 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
	map3k8	Mitogen-activated protein kinase kinase kinase 8. (471 aa)
	LOC101174595	Mitogen-activated protein kinase kinase kinase 14a. (866 aa)
	LOC101174851	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC101154847	Uncharacterized protein. (212 aa)
	LOC101164658	Uncharacterized protein. (242 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	PAK3	Non-specific serine/threonine protein kinase. (590 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (568 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101168152	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101155144	Uncharacterized protein. (466 aa)
	YES1	Tyrosine-protein kinase. (550 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	CDC42	Cell division cycle 42. (191 aa)
	LOC101167902	Tyrosine-protein kinase. (511 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1679 aa)
	mapkap1	MAPK associated protein 1. (529 aa)
	LOC101166422	ADP-ribosylation factor 2b. (976 aa)
	LOC101155451	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
	H2MSU3_ORYLA	Uncharacterized protein. (420 aa)
	LOC101162321	Tyrosine-protein kinase. (547 aa)
	LOC101173752	IGv domain-containing protein. (224 aa)
	LOC101163728	Uncharacterized protein. (409 aa)
	pak1	Non-specific serine/threonine protein kinase. (571 aa)
	LOC101174454	Uncharacterized protein. (191 aa)
	LOC101157019	Tyrosine-protein kinase. (537 aa)
	pik3r3	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (719 aa)
	LOC101164400	Uncharacterized protein. (191 aa)
	LOC101172604	Thioesterase superfamily member 4. (246 aa)
	LOC101162468	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC101169249	Non-specific serine/threonine protein kinase. (514 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	LOC101172297	Uncharacterized protein. (488 aa)
	lck	Tyrosine-protein kinase. (498 aa)
	pak2	Non-specific serine/threonine protein kinase. (532 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)
	LOC101167011	Tyrosine-protein kinase. (526 aa)
	cd276	CD276 molecule. (302 aa)
	H2L4B7_ORYLA	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1023 aa)
	LOC101165394	GRB2 related adaptor protein 2a. (283 aa)
	LOC101174244	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	pik3r1	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	H2MSU3_ORYLA	ENSORLP00000015084	ENSORLP00000021836	Cell division cycle 42.	Uncharacterized protein.	0.494
CDC42	LOC101155451	ENSORLP00000015084	ENSORLP00000017781	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	LOC101157019	ENSORLP00000015084	ENSORLP00000029844	Cell division cycle 42.	Tyrosine-protein kinase.	0.501
CDC42	LOC101162321	ENSORLP00000015084	ENSORLP00000022375	Cell division cycle 42.	Tyrosine-protein kinase.	0.431
CDC42	LOC101162468	ENSORLP00000015084	ENSORLP00000035304	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	LOC101164480	ENSORLP00000015084	ENSORLP00000036233	Cell division cycle 42.	Tyrosine-protein kinase.	0.617
CDC42	LOC101167011	ENSORLP00000015084	ENSORLP00000041511	Cell division cycle 42.	Tyrosine-protein kinase.	0.501
CDC42	LOC101167902	ENSORLP00000015084	ENSORLP00000015921	Cell division cycle 42.	Tyrosine-protein kinase.	0.431
CDC42	LOC101168152	ENSORLP00000015084	ENSORLP00000011212	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.667
CDC42	LOC101169249	ENSORLP00000015084	ENSORLP00000035392	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.942
CDC42	LOC101174244	ENSORLP00000015084	ENSORLP00000001785	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	LOC101174851	ENSORLP00000015084	ENSORLP00000006529	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	PAK3	ENSORLP00000015084	ENSORLP00000008803	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.960
CDC42	PIK3CA	ENSORLP00000015084	ENSORLP00000011211	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.667
CDC42	SRC	ENSORLP00000015084	ENSORLP00000008431	Cell division cycle 42.	Tyrosine-protein kinase.	0.618
CDC42	YES1	ENSORLP00000015084	ENSORLP00000014039	Cell division cycle 42.	Tyrosine-protein kinase.	0.431
CDC42	akt1	ENSORLP00000015084	ENSORLP00000021301	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	grb2	ENSORLP00000015084	ENSORLP00000019097	Cell division cycle 42.	Growth factor receptor-bound protein 2b.	0.698
CDC42	lck	ENSORLP00000015084	ENSORLP00000039217	Cell division cycle 42.	Tyrosine-protein kinase.	0.431
CDC42	pak1	ENSORLP00000015084	ENSORLP00000027320	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.960