STRINGSTRING
PAK3 PAK3 rock1 rock1 fmn2 fmn2 efnb1 efnb1 ENSORLP00000043979 ENSORLP00000043979 LOC101169622 LOC101169622 LOC101174366 LOC101174366 LOC101155777 LOC101155777 wasl wasl LOC101167011 LOC101167011 fndc3a fndc3a LOC101173416 LOC101173416 LOC101159957 LOC101159957 LOC101172697 LOC101172697 ENSORLP00000036561 ENSORLP00000036561 LOC101159909 LOC101159909 LOC101164480 LOC101164480 LOC101164400 LOC101164400 LOC101157019 LOC101157019 LOC101173083 LOC101173083 LOC101174454 LOC101174454 LOC101167426 LOC101167426 LOC101175170 LOC101175170 pak1 pak1 grin2b grin2b LOC101156311 LOC101156311 LOC101162321 LOC101162321 LOC101155523 LOC101155523 LOC101173070 LOC101173070 LOC101158771 LOC101158771 LOC101169951 LOC101169951 LOC101165974 LOC101165974 FMN1 FMN1 LOC101173092 LOC101173092 LOC101169874 LOC101169874 was was CDC42 CDC42 LOC101164501 LOC101164501 fndc3b fndc3b hras hras YES1 YES1 H2M6A2_ORYLA H2M6A2_ORYLA LOC101169846 LOC101169846 arpc3 arpc3 rasa1 rasa1 arpc5 arpc5 LOC101168921 LOC101168921 arpc1a arpc1a LOC101157161 LOC101157161 SRC SRC LOC101164658 LOC101164658 LOC101163273 LOC101163273 LOC101164834 LOC101164834 LOC101172801 LOC101172801 LOC101163953 LOC101163953 LOC101162164 LOC101162164 LOC101158395 LOC101158395 LOC101160196 LOC101160196 actr2 actr2 cfl1 cfl1 LOC101155832 LOC101155832 LOC101157122 LOC101157122 arpc2 arpc2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAK3Non-specific serine/threonine protein kinase. (590 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1364 aa)
fmn2FH2 domain-containing protein. (1391 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (330 aa)
ENSORLP00000043979Uncharacterized protein. (193 aa)
LOC101169622Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (209 aa)
LOC101174366T cell lymphoma invasion and metastasis 1b. (1604 aa)
LOC101155777Uncharacterized protein. (372 aa)
waslUncharacterized protein. (519 aa)
LOC101167011Tyrosine-protein kinase. (526 aa)
fndc3aFibronectin type III domain containing 3A. (1244 aa)
LOC101173416Uncharacterized protein. (566 aa)
LOC101159957Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
LOC101172697Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1401 aa)
ENSORLP00000036561Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (91 aa)
LOC101159909Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (184 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
LOC101164400Uncharacterized protein. (191 aa)
LOC101157019Tyrosine-protein kinase. (537 aa)
LOC101173083T cell lymphoma invasion and metastasis 1a. (1657 aa)
LOC101174454Uncharacterized protein. (191 aa)
LOC101167426Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (381 aa)
LOC101175170Uncharacterized protein. (939 aa)
pak1Non-specific serine/threonine protein kinase. (571 aa)
grin2bUncharacterized protein. (1703 aa)
LOC101156311Eph receptor B2a. (985 aa)
LOC101162321Tyrosine-protein kinase. (547 aa)
LOC101155523Uncharacterized protein. (375 aa)
LOC101173070Uncharacterized protein. (369 aa)
LOC101158771Zgc:86896. (356 aa)
LOC101169951Uncharacterized protein. (330 aa)
LOC101165974Eph receptor B2b. (988 aa)
FMN1Formin 1. (1281 aa)
LOC101173092EPH receptor B1. (1007 aa)
LOC101169874Glutamate receptor, ionotropic, N-methyl D-aspartate 1a. (901 aa)
wasWASP actin nucleation promoting factor a. (561 aa)
CDC42Cell division cycle 42. (191 aa)
LOC101164501ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (159 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
YES1Tyrosine-protein kinase. (550 aa)
H2M6A2_ORYLAIntersectin 1 (SH3 domain protein). (608 aa)
LOC101169846Uncharacterized protein. (990 aa)
arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (179 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1055 aa)
arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
arpc1aActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (365 aa)
LOC101157161Zgc:101810; Belongs to the actin family. (394 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101164658Uncharacterized protein. (242 aa)
LOC101163273Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (91 aa)
LOC101164834FH2 domain-containing protein. (377 aa)
LOC101172801Ephrin RBD domain-containing protein; Belongs to the ephrin family. (342 aa)
LOC101163953Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1552 aa)
LOC101162164Actin related protein 3B; Belongs to the actin family. (429 aa)
LOC101158395Actin related protein 3; Belongs to the actin family. (418 aa)
LOC101160196Ephrin-B3a; Belongs to the ephrin family. (340 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
LOC101155832Uncharacterized protein; Belongs to the actin family. (418 aa)
LOC101157122Actin related protein 2/3 complex, subunit 4. (282 aa)
arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (304 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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