107 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC101166574	Solute carrier family 8 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (987 aa)
	LOC101171864	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
	nos1	Uncharacterized protein. (1438 aa)
	pde11a	Phosphodiesterase. (917 aa)
	pde5a	Phosphodiesterase. (877 aa)
	LOC101161831	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	H2LYJ7_ORYLA	Si:ch211-38m6.7. (274 aa)
	pla2g4a	Phospholipase A2. (745 aa)
	LOC101167610	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (975 aa)
	LOC101161069	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
	LOC101173069	cGMP-dependent protein kinase. (680 aa)
	LOC101155365	Tyrosine-protein kinase. (529 aa)
	pde10a	Phosphodiesterase. (819 aa)
	Itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (1587 aa)
	H2M6Z9_ORYLA	Uncharacterized protein. (615 aa)
	H2M700_ORYLA	Ins145_P3_rec domain-containing protein. (146 aa)
	atp2a3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (941 aa)
	p2rx1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (419 aa)
	LOC101156727	Guanine nucleotide binding protein (G protein), beta 5b. (395 aa)
	LOC101173001	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (461 aa)
	ppp2r5a	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (509 aa)
	atp2a1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1004 aa)
	LOC101159590	Platelet/endothelial cell adhesion molecule 1. (793 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	H2MBB3_ORYLA	Vitellogenin domain-containing protein. (793 aa)
	LOC101158990	Apolipoprotein Bb, tandem duplicate 2. (2459 aa)
	gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (340 aa)
	LOC101155104	Inositol 1,4,5-trisphosphate receptor, type 1b. (2627 aa)
	LOC101155618	cGMP-dependent protein kinase. (691 aa)
	LOC101172160	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC101165996	cGMP-dependent protein kinase. (768 aa)
	LOC101156223	Si:dkey-237i9.8. (782 aa)
	TRPC6	Transient receptor potential cation channel, subfamily C, member 6b; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
	LOC101165153	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (405 aa)
	LOC101168199	WD_REPEATS_REGION domain-containing protein. (340 aa)
	LOC101174771	Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (961 aa)
	H2LGY1_ORYLA	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	gnb5	Guanine nucleotide binding protein (G protein), beta 5a. (364 aa)
	ppp2r5b	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (520 aa)
	TRPC6-2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
	vit-6	Uncharacterized protein. (1725 aa)
	ptgir	Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (348 aa)
	mrvi1	Murine retrovirus integration site 1 homolog. (847 aa)
	LOC101167061	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	pde9a	Phosphodiesterase. (523 aa)
	H2LUB0_ORYLA	GAF domain-containing protein. (244 aa)
	p2rx2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
	LOC101175500	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	LOC101167976	Transient receptor potential cation channel subfamily C member 2b. (756 aa)
	LOC101168800	ORAI calcium release-activated calcium modulator 1b. (225 aa)
	gng2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (78 aa)
	LOC101167700	Inositol 1,4,5-trisphosphate receptor, type 1a. (2664 aa)
	LOC101157167	Receptor expression-enhancing protein. (270 aa)
	LOC101164245	ORAI calcium release-activated calcium modulator 2. (280 aa)
	p2rx4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (464 aa)
	LOC101160819	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1017 aa)
	pla2g7	Platelet-activating factor acetylhydrolase. (443 aa)
	LOC101168467	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	H2MSF0_ORYLA	Si:dkey-121j17.5; Belongs to the protein kinase superfamily. (339 aa)
	prkg2	cGMP-dependent protein kinase. (769 aa)
	LOC101173107	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (478 aa)
	itpr3	Inositol 1,4,5-trisphosphate receptor, type 3. (2309 aa)
	LOC101159180	Uncharacterized protein. (1661 aa)
	H2MX42_ORYLA	Zgc:171775. (273 aa)
	LOC101169753	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (609 aa)
	LOC101161896	ORAI calcium release-activated calcium modulator 1a. (218 aa)
	atp2b2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1257 aa)
	LOC101160731	Mitogen-activated protein kinase. (360 aa)
	reep2	Receptor expression-enhancing protein. (278 aa)
	LOC101169118	Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (1005 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	gnb4	Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
	atp2b3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1189 aa)
	prkg1	cGMP-dependent protein kinase. (684 aa)
	ENSORLP00000030400	PDEase domain-containing protein. (103 aa)
	LOC111946430	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (96 aa)
	LOC101162981	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (953 aa)
	LOC101167929	Phosphodiesterase. (916 aa)
	ol-vit1	Uncharacterized protein. (1675 aa)
	LOC101155708	Solute carrier family 8 member 2a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
	LOC101171284	Solute carrier family 8 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (949 aa)
	LOC101171292	Guanine nucleotide binding protein (G protein), gamma 7. (123 aa)
	gng3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC101166781	Phosphodiesterase. (553 aa)
	gng8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	LOC110016922	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC101162042	Mitogen-activated protein kinase. (361 aa)
	Pde2a	PDEase domain-containing protein. (134 aa)
	LOC101173614	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1236 aa)
	ppp2r5d	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (597 aa)
	p2rx3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
	atp2b1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1250 aa)
	ENSORLP00000037120	Cation_ATPase_N domain-containing protein. (68 aa)
	LOC101161140	Vitellogenin 3, phosvitinless. (1267 aa)
	LOC101157587	Uncharacterized protein. (185 aa)
	LOC101173135	Vitellogenin domain-containing protein. (986 aa)
	ol-gb1	WD_REPEATS_REGION domain-containing protein. (369 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	LOC101155207-2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	PPP2R5C	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (567 aa)
	LOC101172706	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (2240 aa)
	LOC101156458	Apolipoprotein Ba. (4366 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
	slc8a3	Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (925 aa)
	LOC101158622	Solute carrier family 8 member 2b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (982 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000030400	LOC101167929	ENSORLP00000030400	ENSORLP00000032881	PDEase domain-containing protein.	Phosphodiesterase.	0.545
ENSORLP00000030400	Pde2a	ENSORLP00000030400	ENSORLP00000035848	PDEase domain-containing protein.	PDEase domain-containing protein.	0.938
ENSORLP00000030400	pde5a	ENSORLP00000030400	ENSORLP00000045398	PDEase domain-containing protein.	Phosphodiesterase.	0.545
ENSORLP00000037120	LOC101172706	ENSORLP00000037120	ENSORLP00000041237	Cation_ATPase_N domain-containing protein.	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.482
ENSORLP00000037120	LOC101173614	ENSORLP00000037120	ENSORLP00000036200	Cation_ATPase_N domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.482
ENSORLP00000037120	atp2b1	ENSORLP00000037120	ENSORLP00000037010	Cation_ATPase_N domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.482
ENSORLP00000037120	atp2b2	ENSORLP00000037120	ENSORLP00000026384	Cation_ATPase_N domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.482
ENSORLP00000037120	atp2b3	ENSORLP00000037120	ENSORLP00000029520	Cation_ATPase_N domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.482
GNG4	GNG5	ENSORLP00000043590	ENSORLP00000041849	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.717
GNG4	H2LGY1_ORYLA	ENSORLP00000043590	ENSORLP00000005234	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.802
GNG4	LOC101155207-2	ENSORLP00000043590	ENSORLP00000039363	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.734
GNG4	LOC101156727	ENSORLP00000043590	ENSORLP00000016014	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta 5b.	0.912
GNG4	LOC101161831	ENSORLP00000043590	ENSORLP00000045430	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.689
GNG4	LOC101168199	ENSORLP00000043590	ENSORLP00000004503	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	WD_REPEATS_REGION domain-containing protein.	0.890
GNG4	LOC101168467	ENSORLP00000043590	ENSORLP00000020790	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.785
GNG4	LOC101171292	ENSORLP00000043590	ENSORLP00000035205	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), gamma 7.	0.689
GNG4	LOC101175500	ENSORLP00000043590	ENSORLP00000009914	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.890
GNG4	LOC110016922	ENSORLP00000043590	ENSORLP00000035371	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.711
GNG4	LOC111946430	ENSORLP00000043590	ENSORLP00000030431	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.800
GNG4	gnb3	ENSORLP00000043590	ENSORLP00000015882	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 3a.	0.859