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LOC101168134 LOC101168134 LOC101167719 LOC101167719 H2LGY1_ORYLA H2LGY1_ORYLA LOC101166146 LOC101166146 LOC101168199 LOC101168199 CACNA1D CACNA1D LOC105358374 LOC105358374 kcnb1 kcnb1 LOC110016922 LOC110016922 LOC101157701 LOC101157701 gnai2 gnai2 Cacna1d Cacna1d LOC101175365 LOC101175365 LOC101157684 LOC101157684 LOC101163742 LOC101163742 cacnb2 cacnb2 LOC101163277 LOC101163277 gnb5 gnb5 LOC101168718 LOC101168718 LOC100049335 LOC100049335 ENSORLP00000045265 ENSORLP00000045265 LOC101170876 LOC101170876 adcy5 adcy5 LOC101168962 LOC101168962 ADRA2C ADRA2C ol-gb ol-gb RAPGEF5 RAPGEF5 H2LT98_ORYLA H2LT98_ORYLA LOC101159343 LOC101159343 LOC101175016 LOC101175016 LOC101175500 LOC101175500 GNG4 GNG4 Kcnj11 Kcnj11 GNG5 GNG5 LOC101161757 LOC101161757 LOC110015484 LOC110015484 LOC101170273 LOC101170273 ENSORLP00000040530 ENSORLP00000040530 cacna1a cacna1a acsl4 acsl4 LOC101155207-2 LOC101155207-2 ENSORLP00000039236 ENSORLP00000039236 rapgefl1 rapgefl1 ol-gb1 ol-gb1 plcb2 plcb2 gng2 gng2 H2LYX4_ORYLA H2LYX4_ORYLA acsl3 acsl3 LOC101173517 LOC101173517 LOC101171292 LOC101171292 gng3 gng3 gng8 gng8 PLCB1 PLCB1 LOC100049337 LOC100049337 gnai3 gnai3 Itpr2 Itpr2 H2M6Z9_ORYLA H2M6Z9_ORYLA H2M700_ORYLA H2M700_ORYLA slc2a2 slc2a2 LOC101155257 LOC101155257 Kcns3 Kcns3 gnb3 gnb3 LOC101155104 LOC101155104 LOC101156727 LOC101156727 LOC110017390 LOC110017390 LOC101165947 LOC101165947 LOC101161831 LOC101161831 LOC101161353 LOC101161353 LOC101169521 LOC101169521 H2MHV7_ORYLA H2MHV7_ORYLA LOC101167700 LOC101167700 LOC101160964 LOC101160964 LOC101156213 LOC101156213 Adra2a Adra2a LOC101158525 LOC101158525 LOC101172360 LOC101172360 LOC101157265 LOC101157265 LOC100049336 LOC100049336 cd36 cd36 cacna2d1 cacna2d1 abcc8 abcc8 LOC101168467 LOC101168467 LOC101158934 LOC101158934 H2MR69_ORYLA H2MR69_ORYLA H2MSC8_ORYLA H2MSC8_ORYLA LOC101173258 LOC101173258 H2MST1_ORYLA H2MST1_ORYLA marcks marcks itpr3 itpr3 THAP1 THAP1 LOC101157531 LOC101157531 LOC101156079 LOC101156079 prkacb prkacb LOC100049529 LOC100049529 LOC101167824 LOC101167824 adcy6 adcy6 gnb4 gnb4 LOC101164755 LOC101164755 LOC111946430 LOC111946430 LOC101169035 LOC101169035 ENSORLP00000030507 ENSORLP00000030507 cacna2d2 cacna2d2 snx19 snx19 LOC101155154 LOC101155154
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101168134Guanine nucleotide binding protein (G protein), alpha 14. (355 aa)
LOC101167719Uncharacterized protein. (357 aa)
H2LGY1_ORYLAGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC101166146Rap guanine nucleotide exchange factor (GEF) 5a. (899 aa)
LOC101168199WD_REPEATS_REGION domain-containing protein. (340 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1529 aa)
LOC105358374Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
kcnb1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (793 aa)
LOC110016922Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101157701Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
gnai2Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). (355 aa)
Cacna1dCalcium channel, voltage-dependent, L type, alpha 1D subunit, b. (99 aa)
LOC1011753651-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
LOC101157684Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (394 aa)
LOC101163742Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (680 aa)
LOC101163277Calcium channel, voltage-dependent, beta 2b. (653 aa)
gnb5Guanine nucleotide binding protein (G protein), beta 5a. (364 aa)
LOC101168718Uncharacterized protein. (358 aa)
LOC100049335ZP domain-containing protein. (365 aa)
ENSORLP00000045265Uncharacterized protein. (271 aa)
LOC101170876Uncharacterized protein; Belongs to the protein kinase superfamily. (354 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1196 aa)
LOC101168962Guanine nucleotide binding protein (G protein), alpha 14a. (357 aa)
ADRA2CAdrenoceptor alpha 2C. (434 aa)
ol-gbWD_REPEATS_REGION domain-containing protein. (342 aa)
RAPGEF5Uncharacterized protein. (573 aa)
H2LT98_ORYLAVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1226 aa)
LOC101159343Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
LOC101175016Sorting nexin 19a. (878 aa)
LOC101175500Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Kcnj11Potassium inwardly-rectifying channel, subfamily J, member 11. (269 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
LOC101161757ZP domain-containing protein. (372 aa)
LOC110015484Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC101170273Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2397 aa)
ENSORLP00000040530Ion_trans domain-containing protein. (283 aa)
cacna1aCalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. (2285 aa)
acsl4Acyl-CoA synthetase long chain family member 4a. (676 aa)
LOC101155207-2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSORLP00000039236THAP-type domain-containing protein. (96 aa)
rapgefl1Rap guanine nucleotide exchange factor (GEF)-like 1. (653 aa)
ol-gb1WD_REPEATS_REGION domain-containing protein. (369 aa)
plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1248 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (78 aa)
H2LYX4_ORYLASi:dkey-211g8.9. (257 aa)
acsl3Uncharacterized protein. (719 aa)
LOC101173517Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2301 aa)
LOC101171292Guanine nucleotide binding protein (G protein), gamma 7. (123 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1242 aa)
LOC100049337ZP domain-containing protein. (498 aa)
gnai3Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] (354 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (1587 aa)
H2M6Z9_ORYLAUncharacterized protein. (615 aa)
H2M700_ORYLAIns145_P3_rec domain-containing protein. (146 aa)
slc2a2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (505 aa)
LOC101155257Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
Kcns3Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b; Belongs to the potassium channel family. (499 aa)
gnb3Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (340 aa)
LOC101155104Inositol 1,4,5-trisphosphate receptor, type 1b. (2627 aa)
LOC101156727Guanine nucleotide binding protein (G protein), beta 5b. (395 aa)
LOC110017390Potassium voltage-gated channel, subfamily G, member 2; Belongs to the potassium channel family. (533 aa)
LOC101165947Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
LOC101161831Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101161353Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
LOC101169521Adrenoceptor alpha 2C. (449 aa)
H2MHV7_ORYLAVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (649 aa)
LOC101167700Inositol 1,4,5-trisphosphate receptor, type 1a. (2664 aa)
LOC101160964Uncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
LOC101156213Calcium channel, voltage-dependent, alpha 2/delta subunit 1a. (1088 aa)
Adra2aAdrenoceptor alpha 2A. (410 aa)
LOC101158525Rap guanine nucleotide exchange factor (GEF) 3. (798 aa)
LOC101172360Acyl-CoA synthetase long chain family member 3b. (713 aa)
LOC101157265Uncharacterized protein. (354 aa)
LOC100049336ZPC domain containing protein 4. (459 aa)
cd36CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (466 aa)
cacna2d1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (893 aa)
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1565 aa)
LOC101168467Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
LOC101158934Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (400 aa)
H2MR69_ORYLAUncharacterized protein. (425 aa)
H2MSC8_ORYLAUncharacterized protein. (450 aa)
LOC101173258Calcium channel, voltage-dependent, R type, alpha 1E subunit b. (1708 aa)
H2MST1_ORYLARap guanine nucleotide exchange factor (GEF) 4. (421 aa)
marcksMyristoylated alanine-rich protein kinase C substrate a. (289 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2309 aa)
THAP1THAP domain containing 1. (214 aa)
LOC101157531Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2099 aa)
LOC101156079Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1101 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC1000495291-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
LOC101167824Zgc:171558. (1002 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
gnb4Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
LOC101164755ZP domain-containing protein. (459 aa)
LOC111946430Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (96 aa)
LOC101169035Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
ENSORLP00000030507Rap guanine nucleotide exchange factor (GEF) 4. (348 aa)
cacna2d2Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (1107 aa)
snx19Sorting nexin 19b. (950 aa)
LOC101155154Glucagon b. (158 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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