STRINGSTRING
Mtor Mtor LOC101172604 LOC101172604 CSDE1 CSDE1 LOC101164400 LOC101164400 pik3cb pik3cb LOC110016423 LOC110016423 LOC101163742 LOC101163742 vav2 vav2 HSH2D HSH2D prkcd prkcd Rnf222 Rnf222 kras kras LOC101158013 LOC101158013 LOC101157047 LOC101157047 ctnnb1 ctnnb1 ENSORLP00000031454 ENSORLP00000031454 VAV1 VAV1 plcg1 plcg1 LOC101162652 LOC101162652 vegfa vegfa ENSORLP00000030231 ENSORLP00000030231 LOC101154954 LOC101154954 LOC101157019 LOC101157019 LOC101159814 LOC101159814 ncf1 ncf1 LOC101174454 LOC101174454 BAIAP2 BAIAP2 she she pak1 pak1 LOC101160731 LOC101160731 prkcz prkcz prkacb prkacb TGFB1I1 TGFB1I1 Brk1 Brk1 nckap1 nckap1 H2MY81_ORYLA H2MY81_ORYLA H2MX42_ORYLA H2MX42_ORYLA bcar1 bcar1 stx7 stx7 LOC101155523 LOC101155523 LOC101173070 LOC101173070 LOC101169951 LOC101169951 akt1 akt1 LOC101159668 LOC101159668 LOC101169438 LOC101169438 MAPKAPK2 MAPKAPK2 LOC101156647 LOC101156647 LOC101160964 LOC101160964 LOC101175519 LOC101175519 LOC101155451 LOC101155451 LOC101159256 LOC101159256 mapkap1 mapkap1 rictor rictor LOC101173369 LOC101173369 LOC101160322 LOC101160322 CDC42 CDC42 LOC101169506 LOC101169506 fndc3b fndc3b hras hras wasf2 wasf2 LOC101170569 LOC101170569 ncf4 ncf4 rasa1 rasa1 nck1 nck1 crk crk LOC101170217 LOC101170217 cass4 cass4 LOC101168921 LOC101168921 nedd9 nedd9 LOC101154993 LOC101154993 ptk2b ptk2b LOC101175696 LOC101175696 LOC101168152 LOC101168152 PIK3CA PIK3CA wasf3 wasf3 LOC101165595 LOC101165595 LOC101166150 LOC101166150 stx12 stx12 LOC101162283 LOC101162283 LOC101164818 LOC101164818 pdpk1 pdpk1 LOC101169609 LOC101169609 PAK3 PAK3 SRC SRC LOC101160681 LOC101160681 LOC101164658 LOC101164658 LOC101166779 LOC101166779 ncf2 ncf2 LOC101174851 LOC101174851 itgb3 itgb3 LOC101171502 LOC101171502 LOC101168465 LOC101168465 LOC101169868 LOC101169868 mlst8 mlst8 LOC101174244 LOC101174244 LOC101174288 LOC101174288 AXL AXL SPHK1 SPHK1 H2L4B7_ORYLA H2L4B7_ORYLA H2L406_ORYLA H2L406_ORYLA abi2 abi2 LOC101169249 LOC101169249 LOC101170577 LOC101170577 LOC101162042 LOC101162042 LOC101164480 LOC101164480 LOC101172297 LOC101172297 LOC101172697 LOC101172697 ABI1 ABI1 VAV3 VAV3 ptk2 ptk2 SHF SHF nck2 nck2 pak2 pak2 shc2 shc2 ARVCF ARVCF fndc3a fndc3a wasf1 wasf1 LOC101167011 LOC101167011 LOC101155777 LOC101155777 LOC101160624 LOC101160624 LOC101171200 LOC101171200 ctnnd1 ctnnd1 rock1 rock1 LOC101170876 LOC101170876 ENSORLP00000045591 ENSORLP00000045591 LOC101173701 LOC101173701 LOC101162468 LOC101162468
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MtorSerine/threonine-protein kinase TOR. (1023 aa)
LOC101172604Thioesterase superfamily member 4. (246 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (875 aa)
LOC101164400Uncharacterized protein. (191 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
LOC110016423Uncharacterized protein. (313 aa)
LOC101163742Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
vav2Vav 2 guanine nucleotide exchange factor. (922 aa)
HSH2DSH2 domain-containing protein. (327 aa)
prkcdProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
Rnf222RING-type domain-containing protein. (217 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
LOC101158013Src homology 2 domain containing transforming protein D, b. (419 aa)
LOC101157047Leupaxin. (385 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (783 aa)
ENSORLP00000031454Uncharacterized protein. (108 aa)
VAV1Vav guanine nucleotide exchange factor 1. (902 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
LOC101162652FERM domain-containing protein. (274 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
ENSORLP00000030231SH2 domain-containing protein. (116 aa)
LOC101154954Zgc:55558. (189 aa)
LOC101157019Tyrosine-protein kinase. (537 aa)
LOC101159814NCK associated protein 1 like. (1123 aa)
ncf1Neutrophil cytosolic factor 1. (421 aa)
LOC101174454Uncharacterized protein. (191 aa)
BAIAP2BAI1 associated protein 2. (577 aa)
sheSrc homology 2 domain containing E. (469 aa)
pak1Non-specific serine/threonine protein kinase. (571 aa)
LOC101160731Mitogen-activated protein kinase. (360 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (600 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (479 aa)
Brk1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (114 aa)
nckap1NCK-associated protein 1. (1126 aa)
H2MY81_ORYLAFERM_N_2 domain-containing protein. (84 aa)
H2MX42_ORYLAZgc:171775. (273 aa)
bcar1BCAR1 scaffold protein, Cas family member. (947 aa)
stx7Syntaxin 7-like; Belongs to the syntaxin family. (259 aa)
LOC101155523Uncharacterized protein. (375 aa)
LOC101173070Uncharacterized protein. (369 aa)
LOC101169951Uncharacterized protein. (330 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
LOC101159668Mitogen-activated protein kinase. (361 aa)
LOC101169438Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
MAPKAPK2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
LOC101156647Engulfment and cell motility 2. (711 aa)
LOC101160964Uncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
LOC101175519Uncharacterized protein. (464 aa)
LOC101155451Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC101159256Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
mapkap1MAPK associated protein 1. (529 aa)
rictorRPTOR independent companion of MTOR, complex 2 a. (1679 aa)
LOC101173369Junction plakoglobin a. (733 aa)
LOC101160322DAGKc domain-containing protein. (560 aa)
CDC42Cell division cycle 42. (191 aa)
LOC101169506Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (730 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
wasf2WASP family member 2. (471 aa)
LOC101170569Uncharacterized protein. (821 aa)
ncf4Neutrophil cytosolic factor 4. (350 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1055 aa)
nck1Cytoplasmic protein. (392 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
LOC101170217Abl-interactor 1b. (496 aa)
cass4Cas scaffold protein family member 4. (793 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
nedd9Neural precursor cell expressed, developmentally down-regulated 9. (784 aa)
LOC101154993Mitogen-activated protein kinase. (368 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)
LOC101175696Mitogen-activated protein kinase. (354 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
wasf3WASP family member 3b. (486 aa)
LOC101165595Zgc:109889. (553 aa)
LOC101166150Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (198 aa)
stx12Syntaxin 12; Belongs to the syntaxin family. (267 aa)
LOC101162283Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
LOC101164818Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (568 aa)
LOC101169609BAI1-associated protein 2a. (555 aa)
PAK3Non-specific serine/threonine protein kinase. (590 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101160681WH2 domain-containing protein. (450 aa)
LOC101164658Uncharacterized protein. (242 aa)
LOC101166779Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (949 aa)
ncf2Neutrophil cytosolic factor 2. (460 aa)
LOC101174851Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (795 aa)
LOC101171502Uncharacterized protein. (768 aa)
LOC101168465Integrin beta; Belongs to the integrin beta chain family. (754 aa)
LOC101169868ELMO domain-containing protein. (726 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
LOC101174244Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC101174288Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
AXLAXL receptor tyrosine kinase. (939 aa)
SPHK1Sphingosine kinase 1. (467 aa)
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
H2L406_ORYLAMitogen-activated protein kinase. (360 aa)
abi2Uncharacterized protein. (483 aa)
LOC101169249Non-specific serine/threonine protein kinase. (514 aa)
LOC101170577Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
LOC101162042Mitogen-activated protein kinase. (361 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
LOC101172297Uncharacterized protein. (488 aa)
LOC101172697Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1401 aa)
ABI1Abl-interactor 1a. (641 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
ptk2Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
SHFSrc homology 2 domain containing F. (472 aa)
nck2Cytoplasmic protein. (398 aa)
pak2Non-specific serine/threonine protein kinase. (532 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (711 aa)
ARVCFARVCF delta catenin family member b. (1033 aa)
fndc3aFibronectin type III domain containing 3A. (1244 aa)
wasf1WASP family member 1. (583 aa)
LOC101167011Tyrosine-protein kinase. (526 aa)
LOC101155777Uncharacterized protein. (372 aa)
LOC101160624Vav 3 guanine nucleotide exchange factor b. (904 aa)
LOC101171200Embryonal Fyn-associated substrate. (943 aa)
ctnnd1Uncharacterized protein. (918 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1364 aa)
LOC101170876Uncharacterized protein; Belongs to the protein kinase superfamily. (354 aa)
ENSORLP00000045591Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)
LOC101173701Engulfment and cell motility 3. (742 aa)
LOC101162468Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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