22 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rspo2	R-spondin-2. (245 aa)
	rnf43	Ring finger protein 43. (856 aa)
	znrf3	Zinc and ring finger 3. (871 aa)
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (975 aa)
	lrp6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1623 aa)
	rps27a	Ribosomal protein S27a. (195 aa)
	lgr5	G_PROTEIN_RECEP_F1_2 domain-containing protein. (909 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
	lrp5	Low density lipoprotein receptor-related protein 5. (1634 aa)
	rspo1	Uncharacterized protein. (270 aa)
	ubc	Ubiquitin B. (782 aa)
	H2M970_ORYLA	Ubiquitin-like domain-containing protein. (129 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
	H2M3J6_ORYLA	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (564 aa)
	lrtm1	Leucine rich repeats and transmembrane domains 1. (376 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	lgr6	Leucine-rich repeat-containing G protein-coupled receptor 6. (928 aa)
	rspo3	R-spondin-3. (328 aa)
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1078 aa)
	H2L9W7_ORYLA	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fzd8	fzd4	ENSORLP00000006033	ENSORLP00000013516	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.411
Fzd8	lrp5	ENSORLP00000006033	ENSORLP00000026836	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Low density lipoprotein receptor-related protein 5.	0.917
Fzd8	lrp6	ENSORLP00000006033	ENSORLP00000040318	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.917
Fzd8	rnf43	ENSORLP00000006033	ENSORLP00000044600	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Ring finger protein 43.	0.952
Fzd8	rps27a	ENSORLP00000006033	ENSORLP00000038189	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Ribosomal protein S27a.	0.461
Fzd8	ubc	ENSORLP00000006033	ENSORLP00000015065	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Ubiquitin B.	0.486
Fzd8	wnt3a	ENSORLP00000006033	ENSORLP00000035478	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.910
Fzd8	znrf3	ENSORLP00000006033	ENSORLP00000044251	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Zinc and ring finger 3.	0.933
H2L9W7_ORYLA	lrp5	ENSORLP00000002666	ENSORLP00000026836	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low density lipoprotein receptor-related protein 5.	0.917
H2L9W7_ORYLA	lrp6	ENSORLP00000002666	ENSORLP00000040318	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.917
H2L9W7_ORYLA	rnf43	ENSORLP00000002666	ENSORLP00000044600	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Ring finger protein 43.	0.952
H2L9W7_ORYLA	rps27a	ENSORLP00000002666	ENSORLP00000038189	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Ribosomal protein S27a.	0.461
H2L9W7_ORYLA	ubc	ENSORLP00000002666	ENSORLP00000015065	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Ubiquitin B.	0.486
H2L9W7_ORYLA	wnt3a	ENSORLP00000002666	ENSORLP00000035478	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.910
H2L9W7_ORYLA	znrf3	ENSORLP00000002666	ENSORLP00000044251	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Zinc and ring finger 3.	0.933
H2M3J6_ORYLA	fzd4	ENSORLP00000013001	ENSORLP00000013516	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.415
H2M3J6_ORYLA	lrp5	ENSORLP00000013001	ENSORLP00000026836	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low density lipoprotein receptor-related protein 5.	0.917
H2M3J6_ORYLA	lrp6	ENSORLP00000013001	ENSORLP00000040318	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.917
H2M3J6_ORYLA	rnf43	ENSORLP00000013001	ENSORLP00000044600	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Ring finger protein 43.	0.952
H2M3J6_ORYLA	rps27a	ENSORLP00000013001	ENSORLP00000038189	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Ribosomal protein S27a.	0.461