39 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101163644	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (388 aa)
	LOC101155859	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	LOC101170291	Uncharacterized protein. (331 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	LOC101156432	Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
	LOC101175345	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	H2LSE1_ORYLA	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (331 aa)
	LOC101160205	Zgc:109986. (313 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1020 aa)
	atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	ubc	Ubiquitin B. (782 aa)
	LOC101169311	Translocase of outer mitochondrial membrane 20. (146 aa)
	CSNK2A2	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (359 aa)
	mterf3	Mitochondrial transcription termination factor 3. (425 aa)
	tomm40	Translocase of outer mitochondrial membrane 40 homolog (yeast). (342 aa)
	fundc1	Uncharacterized protein. (165 aa)
	LOC101167046	Unc-51 like autophagy activating kinase 1a. (916 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (297 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	pink1	PTEN induced kinase 1. (577 aa)
	tomm70	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (577 aa)
	sqstm1	Sequestosome 1. (436 aa)
	map1lc3a	Microtubule-associated protein 1 light chain 3 alpha. (121 aa)
	mfn2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	LOC101172049	Translocase of outer mitochondrial membrane 20b. (146 aa)
	TOMM7	Translocase of outer mitochondrial membrane 7. (55 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	vdac1	Voltage-dependent anion channel 1. (299 aa)
	map1lc3b	RNA-dependent DNA polymerase. (126 aa)
	tomm22	Translocase of outer mitochondrial membrane 22 homolog (yeast). (135 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)
	LOC101160680	Unc-51 like autophagy activating kinase 2. (1031 aa)
	tomm5	Translocase of outer mitochondrial membrane 5 homolog (yeast). (115 aa)
	tomm6	Translocase of outer mitochondrial membrane 6 homolog (yeast). (64 aa)
	LOC101173532	FUN14 domain containing 1. (152 aa)
	ENSORLP00000044224	Fzo_mitofusin domain-containing protein. (297 aa)
	mfn1	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (761 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSNK2A2	LOC101155859	ENSORLP00000015608	ENSORLP00000002594	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.947
CSNK2A2	LOC101156432	ENSORLP00000015608	ENSORLP00000008492	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Zgc:86598; Belongs to the protein kinase superfamily.	0.777
CSNK2A2	LOC101163644	ENSORLP00000015608	ENSORLP00000000087	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.548
CSNK2A2	LOC101173532	ENSORLP00000015608	ENSORLP00000043618	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	FUN14 domain containing 1.	0.519
CSNK2A2	LOC101175345	ENSORLP00000015608	ENSORLP00000008637	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.947
CSNK2A2	fundc1	ENSORLP00000015608	ENSORLP00000017245	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.519
ENSORLP00000044224	H2LSE1_ORYLA	ENSORLP00000044224	ENSORLP00000009002	Fzo_mitofusin domain-containing protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.928
ENSORLP00000044224	atg12	ENSORLP00000044224	ENSORLP00000014536	Fzo_mitofusin domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.631
ENSORLP00000044224	atg5	ENSORLP00000044224	ENSORLP00000019636	Fzo_mitofusin domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.670
ENSORLP00000044224	map1lc3a	ENSORLP00000044224	ENSORLP00000026217	Fzo_mitofusin domain-containing protein.	Microtubule-associated protein 1 light chain 3 alpha.	0.495
ENSORLP00000044224	map1lc3b	ENSORLP00000044224	ENSORLP00000039408	Fzo_mitofusin domain-containing protein.	RNA-dependent DNA polymerase.	0.495
ENSORLP00000044224	mfn2	ENSORLP00000044224	ENSORLP00000026370	Fzo_mitofusin domain-containing protein.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.514
ENSORLP00000044224	pink1	ENSORLP00000044224	ENSORLP00000020035	Fzo_mitofusin domain-containing protein.	PTEN induced kinase 1.	0.812
ENSORLP00000044224	prkn	ENSORLP00000044224	ENSORLP00000045716	Fzo_mitofusin domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.892
ENSORLP00000044224	sqstm1	ENSORLP00000044224	ENSORLP00000025483	Fzo_mitofusin domain-containing protein.	Sequestosome 1.	0.660
ENSORLP00000044224	ubc	ENSORLP00000044224	ENSORLP00000015065	Fzo_mitofusin domain-containing protein.	Ubiquitin B.	0.579
ENSORLP00000044224	vdac1	ENSORLP00000044224	ENSORLP00000039231	Fzo_mitofusin domain-containing protein.	Voltage-dependent anion channel 1.	0.661
H2LSE1_ORYLA	ENSORLP00000044224	ENSORLP00000009002	ENSORLP00000044224	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Fzo_mitofusin domain-containing protein.	0.928
H2LSE1_ORYLA	LOC101173532	ENSORLP00000009002	ENSORLP00000043618	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	FUN14 domain containing 1.	0.486
H2LSE1_ORYLA	atg12	ENSORLP00000009002	ENSORLP00000014536	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.696