17 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPHK1	Sphingosine kinase 1. (467 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (568 aa)
	LOC101162283	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1055 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	LOC101160322	DAGKc domain-containing protein. (560 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (600 aa)
	LOC101154954	Zgc:55558. (189 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	kras	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
	prkcd	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (875 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1244 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC101162283	ENSORLP00000034821	ENSORLP00000009867	Cold shock domain containing E1, RNA-binding.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.509
CSDE1	LOC101164480	ENSORLP00000034821	ENSORLP00000036233	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.417
CSDE1	SRC	ENSORLP00000034821	ENSORLP00000008431	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.417
CSDE1	pdpk1	ENSORLP00000034821	ENSORLP00000009715	Cold shock domain containing E1, RNA-binding.	3-phosphoinositide dependent protein kinase 1b.	0.523
CSDE1	prkcd	ENSORLP00000034821	ENSORLP00000032273	Cold shock domain containing E1, RNA-binding.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.509
CSDE1	prkcz	ENSORLP00000034821	ENSORLP00000026953	Cold shock domain containing E1, RNA-binding.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.480
CSDE1	rasa1	ENSORLP00000034821	ENSORLP00000012485	Cold shock domain containing E1, RNA-binding.	RAS p21 protein activator (GTPase activating protein) 1a.	0.813
LOC101154954	LOC101162283	ENSORLP00000030026	ENSORLP00000009867	Zgc:55558.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.509
LOC101154954	LOC101164480	ENSORLP00000030026	ENSORLP00000036233	Zgc:55558.	Tyrosine-protein kinase.	0.530
LOC101154954	SRC	ENSORLP00000030026	ENSORLP00000008431	Zgc:55558.	Tyrosine-protein kinase.	0.459
LOC101154954	hras	ENSORLP00000030026	ENSORLP00000014318	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.911
LOC101154954	kras	ENSORLP00000030026	ENSORLP00000031976	Zgc:55558.	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.	0.901
LOC101154954	pdpk1	ENSORLP00000030026	ENSORLP00000009715	Zgc:55558.	3-phosphoinositide dependent protein kinase 1b.	0.523
LOC101154954	prkcd	ENSORLP00000030026	ENSORLP00000032273	Zgc:55558.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.509
LOC101154954	prkcz	ENSORLP00000030026	ENSORLP00000026953	Zgc:55558.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.480
LOC101154954	rasa1	ENSORLP00000030026	ENSORLP00000012485	Zgc:55558.	RAS p21 protein activator (GTPase activating protein) 1a.	0.980
LOC101160322	SPHK1	ENSORLP00000015688	ENSORLP00000000841	DAGKc domain-containing protein.	Sphingosine kinase 1.	0.901
LOC101160322	prkcz	ENSORLP00000015688	ENSORLP00000026953	DAGKc domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.488
LOC101162283	CSDE1	ENSORLP00000009867	ENSORLP00000034821	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Cold shock domain containing E1, RNA-binding.	0.509
LOC101162283	LOC101154954	ENSORLP00000009867	ENSORLP00000030026	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Zgc:55558.	0.509