STRINGSTRING
ENSORLP00000032709 ENSORLP00000032709 LOC101160561 LOC101160561 ENSORLP00000031974 ENSORLP00000031974 ENSORLP00000031965 ENSORLP00000031965 ENSORLP00000031809 ENSORLP00000031809 ENSORLP00000031706 ENSORLP00000031706 ENSORLP00000031530 ENSORLP00000031530 rad51ap1 rad51ap1 ENSORLP00000030959 ENSORLP00000030959 LOC101155571 LOC101155571 mdc1 mdc1 ENSORLP00000030122 ENSORLP00000030122 ENSORLP00000030024 ENSORLP00000030024 lig3 lig3 ENSORLP00000029565 ENSORLP00000029565 recql4 recql4 ENSORLP00000029266 ENSORLP00000029266 pold4 pold4 ENSORLP00000026921 ENSORLP00000026921 ankrd12 ankrd12 Atm Atm ENSORLP00000026261 ENSORLP00000026261 ENSORLP00000026204 ENSORLP00000026204 rfc4 rfc4 Rif1 Rif1 LOC101165536 LOC101165536 ccna2 ccna2 Rad51c Rad51c exd2 exd2 H2MZJ4_ORYLA H2MZJ4_ORYLA rfc2 rfc2 tipin tipin babam2 babam2 H2MVD7_ORYLA H2MVD7_ORYLA rad51 rad51 cdca7 cdca7 SPIDR SPIDR ppp4c ppp4c rad17 rad17 dclre1c dclre1c pole4 pole4 xrcc5 xrcc5 rad51d rad51d LOC111947810 LOC111947810 sirt6 sirt6 Brcc3 Brcc3 eme1 eme1 tdp1 tdp1 LOC101162291 LOC101162291 dntt dntt ENSORLP00000043601 ENSORLP00000043601 LOC101169669 LOC101169669 ENSORLP00000043225 ENSORLP00000043225 ENSORLP00000042990 ENSORLP00000042990 Rbbp8 Rbbp8 ENSORLP00000042904 ENSORLP00000042904 ENSORLP00000042896 ENSORLP00000042896 LOC101160001 LOC101160001 ENSORLP00000042721 ENSORLP00000042721 ENSORLP00000042402 ENSORLP00000042402 ENSORLP00000042234 ENSORLP00000042234 ENSORLP00000041938 ENSORLP00000041938 slx4 slx4 ENSORLP00000032397 ENSORLP00000032397 ENSORLP00000041753 ENSORLP00000041753 LOC101169441 LOC101169441 ENSORLP00000041490 ENSORLP00000041490 abl1 abl1 ENSORLP00000041457 ENSORLP00000041457 ENSORLP00000041309 ENSORLP00000041309 LOC101166932 LOC101166932 ENSORLP00000040440 ENSORLP00000040440 LOC101155571-3 LOC101155571-3 ENSORLP00000040033 ENSORLP00000040033 ENSORLP00000039950 ENSORLP00000039950 xrcc1 xrcc1 uimc1 uimc1 LOC101155824-4 LOC101155824-4 LOC101159022 LOC101159022 ENSORLP00000039392 ENSORLP00000039392 brca2 brca2 ENSORLP00000039194 ENSORLP00000039194 hus1 hus1 LOC101155824 LOC101155824 pole3 pole3 sumo1 sumo1 parp3 parp3 polm polm ppp5c ppp5c H4C7 H4C7 polk polk babam1 babam1 uba52 uba52 paxip1 paxip1 LOC101164410 LOC101164410 ENSORLP00000038812 ENSORLP00000038812 ENSORLP00000038728 ENSORLP00000038728 rpa3 rpa3 rps27a rps27a ENSORLP00000038070 ENSORLP00000038070 ENSORLP00000038056 ENSORLP00000038056 ENSORLP00000038003 ENSORLP00000038003 ENSORLP00000027842 ENSORLP00000027842 rcbtb2 rcbtb2 ENSORLP00000027985 ENSORLP00000027985 ENSORLP00000028101 ENSORLP00000028101 ENSORLP00000028253 ENSORLP00000028253 ube2v2 ube2v2 blm blm ENSORLP00000027128 ENSORLP00000027128 ENSORLP00000027208 ENSORLP00000027208 ENSORLP00000027276 ENSORLP00000027276 ENSORLP00000027619 ENSORLP00000027619 ENSORLP00000027695 ENSORLP00000027695 ENSORLP00000027785 ENSORLP00000027785 rad50 rad50 ENSORLP00000037754 ENSORLP00000037754 RNF169 RNF169 ENSORLP00000037569 ENSORLP00000037569 ENSORLP00000037560 ENSORLP00000037560 pcna pcna LOC101155824-3 LOC101155824-3 ENSORLP00000037357 ENSORLP00000037357 lig4 lig4 slf1 slf1 apbb1 apbb1 ENSORLP00000045944 ENSORLP00000045944 xrcc2 xrcc2 ENSORLP00000045767 ENSORLP00000045767 ENSORLP00000045709 ENSORLP00000045709 ENSORLP00000045626 ENSORLP00000045626 ube2i ube2i parp2 parp2 abraxas1 abraxas1 eya1 eya1 ENSORLP00000045078 ENSORLP00000045078 rad9b rad9b ENSORLP00000044831 ENSORLP00000044831 ENSORLP00000044710 ENSORLP00000044710 ENSORLP00000044443 ENSORLP00000044443 rfc1 rfc1 ENSORLP00000044186 ENSORLP00000044186 palb2 palb2 LOC101155571-4 LOC101155571-4 gen1 gen1 ENSORLP00000043739 ENSORLP00000043739 ENSORLP00000043737 ENSORLP00000043737 ENSORLP00000037314 ENSORLP00000037314 ENSORLP00000037276 ENSORLP00000037276 ENSORLP00000037255 ENSORLP00000037255 ENSORLP00000037248 ENSORLP00000037248 LOC101173980 LOC101173980 ENSORLP00000037118 ENSORLP00000037118 LOC101155824-2 LOC101155824-2 ENSORLP00000036824 ENSORLP00000036824 fen1 fen1 mus81 mus81 sumo4 sumo4 kat5 kat5 ENSORLP00000036193 ENSORLP00000036193 LOC101170318 LOC101170318 ENSORLP00000036064 ENSORLP00000036064 smarca5 smarca5 ENSORLP00000035982 ENSORLP00000035982 rhno1 rhno1 ENSORLP00000035482 ENSORLP00000035482 ENSORLP00000035462 ENSORLP00000035462 ENSORLP00000035450 ENSORLP00000035450 ENSORLP00000035375 ENSORLP00000035375 rfc5 rfc5 ENSORLP00000035066 ENSORLP00000035066 ENSORLP00000034792 ENSORLP00000034792 ENSORLP00000034640 ENSORLP00000034640 ENSORLP00000034633 ENSORLP00000034633 ENSORLP00000034408 ENSORLP00000034408 nsd2 nsd2 ENSORLP00000034031 ENSORLP00000034031 ENSORLP00000034014 ENSORLP00000034014 tdrd3 tdrd3 ENSORLP00000033822 ENSORLP00000033822 ENSORLP00000033513 ENSORLP00000033513 tp53bp1 tp53bp1 ENSORLP00000033437 ENSORLP00000033437 ENSORLP00000032954 ENSORLP00000032954 chek2 chek2 POLE POLE mre11 mre11 H2LR68_ORYLA H2LR68_ORYLA LOC101173928 LOC101173928 polh polh tp53 tp53 rad1 rad1 chek1 chek1 ankrd11 ankrd11 LOC101165789 LOC101165789 prkdc prkdc cnppd1 cnppd1 Polq Polq rmi1 rmi1 pias4 pias4 rmi2 rmi2 rpa1 rpa1 LOC101157486 LOC101157486 brca1 brca1 CDCA7L CDCA7L ccna1 ccna1 rfc3 rfc3 rad9a rad9a RPA1 RPA1 sumo2 sumo2 meiob meiob xrcc6 xrcc6 pold3 pold3 exo1 exo1 nhej1 nhej1 H2L743_ORYLA H2L743_ORYLA H2L736_ORYLA H2L736_ORYLA EME2 EME2 cdk2 cdk2 ENSORLP00000028367 ENSORLP00000028367 ENSORLP00000028582 ENSORLP00000028582 eya4 eya4 LOC100049216 LOC100049216 sumo2-2 sumo2-2 dna2 dna2 rad52 rad52 kxd1 kxd1 ppp4r2 ppp4r2 ube2n ube2n pold1 pold1 baz1b baz1b HIST1H4J HIST1H4J H2M8G3_ORYLA H2M8G3_ORYLA RCBTB1 RCBTB1 rnf8 rnf8 H2M970_ORYLA H2M970_ORYLA ubc ubc sirt7 sirt7 atr atr topbp1 topbp1 tmem182 tmem182 pold2 pold2 tdp2 tdp2 pole2 pole2 poll poll LOC101169703 LOC101169703 parp1 parp1 KPNA2 KPNA2 top3a top3a rpa2 rpa2 ENSORLP00000032044 ENSORLP00000032044 timeless timeless LOC101155571-2 LOC101155571-2 ENSORLP00000032367 ENSORLP00000032367 ENSORLP00000041768 ENSORLP00000041768 ENSORLP00000032456 ENSORLP00000032456 ENSORLP00000032466 ENSORLP00000032466 ENSORLP00000032655 ENSORLP00000032655
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSORLP00000032709Reverse transcriptase domain-containing protein. (444 aa)
LOC101160561Importin subunit alpha; Belongs to the importin alpha family. (522 aa)
ENSORLP00000031974Reverse transcriptase domain-containing protein. (380 aa)
ENSORLP00000031965Reverse transcriptase domain-containing protein. (1239 aa)
ENSORLP00000031809Reverse transcriptase domain-containing protein. (1242 aa)
ENSORLP00000031706Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSORLP00000031530Reverse transcriptase domain-containing protein. (1095 aa)
rad51ap1RAD51 associated protein 1. (315 aa)
ENSORLP00000030959Uncharacterized protein. (229 aa)
LOC101155571Histone H2B; Belongs to the histone H2B family. (124 aa)
mdc1Uncharacterized protein. (1949 aa)
ENSORLP00000030122Reverse transcriptase domain-containing protein. (374 aa)
ENSORLP00000030024Reverse transcriptase domain-containing protein. (1000 aa)
lig3DNA ligase. (1011 aa)
ENSORLP00000029565Reverse transcriptase domain-containing protein. (925 aa)
recql4RecQ helicase-like 4. (1546 aa)
ENSORLP00000029266Reverse transcriptase domain-containing protein. (1253 aa)
pold4Si:dkey-28b4.7. (108 aa)
ENSORLP00000026921Reverse transcriptase domain-containing protein. (1102 aa)
ankrd12Ankyrin repeat domain 12. (1906 aa)
AtmUncharacterized protein. (147 aa)
ENSORLP00000026261UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa)
ENSORLP00000026204Reverse transcriptase domain-containing protein. (323 aa)
rfc4Replication factor C (activator 1) 4. (355 aa)
Rif1Uncharacterized protein. (1520 aa)
LOC101165536Importin subunit alpha; Belongs to the importin alpha family. (510 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (429 aa)
Rad51cRAD51 paralog C. (307 aa)
exd2Exonuclease 3'-5' domain containing 2. (623 aa)
H2MZJ4_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (144 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (311 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
H2MVD7_ORYLADNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (308 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (396 aa)
cdca7Cell division cycle associated 7a. (391 aa)
SPIDRScaffold protein involved in DNA repair. (885 aa)
ppp4cSerine/threonine-protein phosphatase. (311 aa)
rad17RAD17 checkpoint clamp loader component. (621 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (622 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (124 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
rad51dRAD51 paralog D. (332 aa)
LOC111947810Importin subunit alpha; Belongs to the importin alpha family. (506 aa)
sirt6Sirtuin 6. (347 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (296 aa)
eme1Essential meiotic structure-specific endonuclease 1. (459 aa)
tdp1Tyrosyl-DNA phosphodiesterase 1. (616 aa)
LOC101162291Uncharacterized protein. (378 aa)
dnttDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa)
ENSORLP00000043601Reverse transcriptase domain-containing protein. (657 aa)
LOC101169669Uncharacterized protein. (323 aa)
ENSORLP00000043225Reverse transcriptase domain-containing protein. (968 aa)
ENSORLP00000042990Reverse transcriptase domain-containing protein. (1076 aa)
Rbbp8SAE2 domain-containing protein. (78 aa)
ENSORLP00000042904Reverse transcriptase domain-containing protein. (1074 aa)
ENSORLP00000042896annotation not available (132 aa)
LOC101160001ANK_REP_REGION domain-containing protein. (658 aa)
ENSORLP00000042721Reverse transcriptase domain-containing protein. (495 aa)
ENSORLP00000042402Reverse transcriptase domain-containing protein. (1078 aa)
ENSORLP00000042234Reverse transcriptase domain-containing protein. (1248 aa)
ENSORLP00000041938Reverse transcriptase domain-containing protein. (1249 aa)
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1590 aa)
ENSORLP00000032397Reverse transcriptase domain-containing protein. (479 aa)
ENSORLP00000041753Reverse transcriptase domain-containing protein. (954 aa)
LOC101169441Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (481 aa)
ENSORLP00000041490Reverse transcriptase domain-containing protein. (538 aa)
abl1Tyrosine-protein kinase. (1106 aa)
ENSORLP00000041457Reverse transcriptase domain-containing protein. (891 aa)
ENSORLP00000041309Reverse transcriptase domain-containing protein. (800 aa)
LOC101166932X-ray repair complementing defective repair in Chinese hamster cells 4. (336 aa)
ENSORLP00000040440Reverse transcriptase domain-containing protein. (1236 aa)
LOC101155571-3Histone H2B 1/2. (124 aa)
ENSORLP00000040033Reverse transcriptase domain-containing protein. (421 aa)
ENSORLP00000039950Reverse transcriptase domain-containing protein. (954 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
uimc1Uncharacterized protein. (838 aa)
LOC101155824-4Histone H4. (103 aa)
LOC101159022Uncharacterized protein. (298 aa)
ENSORLP00000039392Reverse transcriptase domain-containing protein. (1262 aa)
brca2BRCA2 DNA repair associated. (3161 aa)
ENSORLP00000039194annotation not available (855 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (299 aa)
LOC101155824Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
pole3CBFD_NFYB_HMF domain-containing protein. (148 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
parp3Poly [ADP-ribose] polymerase. (526 aa)
polmDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (472 aa)
ppp5cSerine/threonine-protein phosphatase. (491 aa)
H4C7Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (158 aa)
polkPolymerase (DNA directed) kappa. (871 aa)
babam1BRISC and BRCA1 A complex member 1. (377 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
paxip1PAX interacting (with transcription-activation domain) protein 1. (1107 aa)
LOC101164410Uncharacterized protein. (248 aa)
ENSORLP00000038812Reverse transcriptase domain-containing protein. (271 aa)
ENSORLP00000038728Reverse transcriptase domain-containing protein. (1071 aa)
rpa3Replication protein A3. (122 aa)
rps27aRibosomal protein S27a. (195 aa)
ENSORLP00000038070Zgc:171759; Belongs to the histone H2B family. (207 aa)
ENSORLP00000038056Reverse transcriptase domain-containing protein. (1240 aa)
ENSORLP00000038003Uncharacterized protein. (126 aa)
ENSORLP00000027842Reverse transcriptase domain-containing protein. (803 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSORLP00000027985Reverse transcriptase domain-containing protein. (853 aa)
ENSORLP00000028101Reverse transcriptase domain-containing protein. (1240 aa)
ENSORLP00000028253Reverse transcriptase domain-containing protein. (1038 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (177 aa)
blmUncharacterized protein. (1393 aa)
ENSORLP00000027128Reverse transcriptase domain-containing protein. (851 aa)
ENSORLP00000027208Reverse transcriptase domain-containing protein. (402 aa)
ENSORLP00000027276Reverse transcriptase domain-containing protein. (1441 aa)
ENSORLP00000027619TAN domain-containing protein. (321 aa)
ENSORLP00000027695Reverse transcriptase domain-containing protein. (1076 aa)
ENSORLP00000027785Reverse transcriptase domain-containing protein. (902 aa)
rad50RAD50 homolog, double strand break repair protein. (1311 aa)
ENSORLP00000037754Reverse transcriptase domain-containing protein. (923 aa)
RNF169Ring finger protein 169. (608 aa)
ENSORLP00000037569Reverse transcriptase domain-containing protein. (1153 aa)
ENSORLP00000037560Reverse transcriptase domain-containing protein. (772 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
LOC101155824-3Histone H4. (103 aa)
ENSORLP00000037357Reverse transcriptase domain-containing protein. (1203 aa)
lig4DNA ligase. (912 aa)
slf1SMC5-SMC6 complex localization factor 1. (900 aa)
apbb1Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65). (687 aa)
ENSORLP00000045944Reverse transcriptase domain-containing protein. (1241 aa)
xrcc2X-ray repair cross complementing 2. (313 aa)
ENSORLP00000045767Reverse transcriptase domain-containing protein. (1239 aa)
ENSORLP00000045709Reverse transcriptase domain-containing protein. (543 aa)
ENSORLP00000045626Histone H2B; Belongs to the histone H2B family. (199 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
parp2Poly [ADP-ribose] polymerase. (649 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (387 aa)
eya1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (608 aa)
ENSORLP00000045078Uncharacterized protein. (646 aa)
rad9bRAD9 checkpoint clamp component B. (402 aa)
ENSORLP00000044831Reverse transcriptase domain-containing protein. (855 aa)
ENSORLP00000044710annotation not available (829 aa)
ENSORLP00000044443Reverse transcriptase domain-containing protein. (1076 aa)
rfc1Replication factor C subunit 1. (1152 aa)
ENSORLP00000044186Reverse transcriptase domain-containing protein. (1243 aa)
palb2PALB2_WD40 domain-containing protein. (1311 aa)
LOC101155571-4Histone H2B 1/2. (124 aa)
gen1Uncharacterized protein. (876 aa)
ENSORLP00000043739Reverse transcriptase domain-containing protein. (805 aa)
ENSORLP00000043737Reverse transcriptase domain-containing protein. (1243 aa)
ENSORLP00000037314Reverse transcriptase domain-containing protein. (1241 aa)
ENSORLP00000037276annotation not available (783 aa)
ENSORLP00000037255Reverse transcriptase domain-containing protein. (889 aa)
ENSORLP00000037248Reverse transcriptase domain-containing protein. (938 aa)
LOC101173980Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (269 aa)
ENSORLP00000037118annotation not available (1248 aa)
LOC101155824-2Histone H4. (103 aa)
ENSORLP00000036824Uncharacterized protein. (311 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (432 aa)
mus81MUS81 structure-specific endonuclease subunit. (656 aa)
sumo4Small ubiquitin-related modifier. (101 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (580 aa)
ENSORLP00000036193Reverse transcriptase domain-containing protein. (1249 aa)
LOC101170318UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
ENSORLP00000036064Reverse transcriptase domain-containing protein. (1025 aa)
smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1039 aa)
ENSORLP00000035982Reverse transcriptase domain-containing protein. (1283 aa)
rhno1Si:ch73-352p4.5. (266 aa)
ENSORLP00000035482Reverse transcriptase domain-containing protein. (431 aa)
ENSORLP00000035462Reverse transcriptase domain-containing protein. (855 aa)
ENSORLP00000035450Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSORLP00000035375Reverse transcriptase domain-containing protein. (920 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSORLP00000035066Reverse transcriptase domain-containing protein. (903 aa)
ENSORLP00000034792Reverse transcriptase domain-containing protein. (845 aa)
ENSORLP00000034640Reverse transcriptase domain-containing protein. (1175 aa)
ENSORLP00000034633Reverse transcriptase domain-containing protein. (1076 aa)
ENSORLP00000034408Reverse transcriptase domain-containing protein. (961 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1283 aa)
ENSORLP00000034031Reverse transcriptase domain-containing protein. (1278 aa)
ENSORLP00000034014Reverse transcriptase domain-containing protein. (1314 aa)
tdrd3Tudor domain containing 3. (799 aa)
ENSORLP00000033822Reverse transcriptase domain-containing protein. (1068 aa)
ENSORLP00000033513DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (398 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1583 aa)
ENSORLP00000033437Reverse transcriptase domain-containing protein. (955 aa)
ENSORLP00000032954Reverse transcriptase domain-containing protein. (1115 aa)
chek2Checkpoint kinase 2. (526 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1100 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (694 aa)
H2LR68_ORYLAHistone H2A; Belongs to the histone H2A family. (131 aa)
LOC101173928Lysine (K)-specific demethylase 4B. (1068 aa)
polhPolymerase (DNA directed), eta. (708 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
rad1RAD1 homolog (S. pombe). (282 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (454 aa)
ankrd11Ankyrin repeat domain 11. (2833 aa)
LOC101165789Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (589 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3962 aa)
cnppd1Cyclin Pas1/PHO80 domain containing 1. (399 aa)
PolqPOLAc domain-containing protein. (1680 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (648 aa)
pias4Protein inhibitor of activated STAT, 4a. (503 aa)
rmi2RecQ mediated genome instability 2. (140 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
LOC101157486Zgc:110269. (329 aa)
brca1Uncharacterized protein. (1292 aa)
CDCA7Lzf-4CXXC_R1 domain-containing protein. (414 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (413 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (388 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa)
sumo2Small ubiquitin-related modifier. (96 aa)
meiobMethionine sulfoxide reductase B1b. (462 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (611 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
exo1Exonuclease 1. (749 aa)
nhej1Nonhomologous end-joining factor 1. (312 aa)
H2L743_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
H2L736_ORYLAHistone H2B; Belongs to the histone H2B family. (132 aa)
EME2ERCC4 domain-containing protein. (443 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
ENSORLP00000028367Reverse transcriptase domain-containing protein. (671 aa)
ENSORLP00000028582Reverse transcriptase domain-containing protein. (1003 aa)
eya4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (642 aa)
LOC100049216Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (574 aa)
sumo2-2Small ubiquitin-related modifier. (95 aa)
dna2DNA replication helicase/nuclease 2. (1396 aa)
rad52RAD52 homolog, DNA repair protein. (422 aa)
kxd1KxDL motif containing 1. (184 aa)
ppp4r2Protein phosphatase 4, regulatory subunit 2b. (422 aa)
ube2nUbiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
pold1DNA polymerase. (1107 aa)
baz1bBromodomain adjacent to zinc finger domain, 1B. (1570 aa)
HIST1H4JHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
H2M8G3_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (516 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
ubcUbiquitin B. (782 aa)
sirt7Sirtuin 7. (408 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2160 aa)
topbp1DNA topoisomerase II binding protein 1. (1460 aa)
tmem182Transmembrane protein 182a. (243 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (524 aa)
tdp2Tyrosyl-DNA phosphodiesterase 2b. (359 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (577 aa)
LOC101169703UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
KPNA2Importin subunit alpha; Belongs to the importin alpha family. (519 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa)
rpa2Replication protein A2. (280 aa)
ENSORLP00000032044Reverse transcriptase domain-containing protein. (488 aa)
timelessTimeless circadian clock. (1244 aa)
LOC101155571-2Histone H2B 1/2. (124 aa)
ENSORLP00000032367Reverse transcriptase domain-containing protein. (954 aa)
ENSORLP00000041768Reverse transcriptase domain-containing protein. (782 aa)
ENSORLP00000032456Reverse transcriptase domain-containing protein. (1248 aa)
ENSORLP00000032466Reverse transcriptase domain-containing protein. (824 aa)
ENSORLP00000032655Reverse transcriptase domain-containing protein. (1262 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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