57 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sumo1	Small ubiquitin-related modifier. (101 aa)
	parp3	Poly [ADP-ribose] polymerase. (526 aa)
	cetn3	Centrin 3. (166 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (845 aa)
	ddb1	Damage-specific DNA binding protein 1. (1126 aa)
	usp45	Ubiquitin carboxyl-terminal hydrolase. (791 aa)
	ercc4	Excision repair cross-complementation group 4. (889 aa)
	meiob	Methionine sulfoxide reductase B1b. (462 aa)
	sumo2	Small ubiquitin-related modifier. (96 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa)
	chd1l	Chromodomain helicase DNA binding protein 1-like. (900 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	LOC101154851	Cullin 4A; Belongs to the cullin family. (612 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
	ercc5	Excision repair cross-complementation group 5. (1078 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (472 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	ddb2	Damage-specific DNA binding protein 2. (488 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	sumo2-2	Small ubiquitin-related modifier. (95 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (386 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
	ube2n	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	H2M970_ORYLA	Ubiquitin-like domain-containing protein. (129 aa)
	ubc	Ubiquitin B. (782 aa)
	wdr76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (543 aa)
	LOC101169703	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	H2MG95_ORYLA	Ring-box 1, E3 ubiquitin protein ligase. (82 aa)
	rpa2	Replication protein A2. (280 aa)
	bivm	Basic, immunoglobulin-like variable motif containing. (506 aa)
	ercc1	Excision repair cross-complementation group 1. (341 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (277 aa)
	LOC101160651	Protein inhibitor of activated STAT, 1b. (653 aa)
	ENSORLP00000026261	UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	ube2v2	Ubiquitin-conjugating enzyme E2 variant 2. (177 aa)
	kctd2	Potassium channel tetramerization domain containing 2. (269 aa)
	rad23a	RAD23 homolog A, nucleotide excision repair protein a. (363 aa)
	ercc2	Excision repair cross-complementation group 2. (761 aa)
	LOC101169428	Protein inhibitor of activated STAT, 1a. (714 aa)
	ENSORLP00000033776	Si:cabz01080528.1. (633 aa)
	LOC101170318	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (326 aa)
	sumo4	Small ubiquitin-related modifier. (101 aa)
	rnf111	Ring finger protein 111. (1017 aa)
	rps27a	Ribosomal protein S27a. (195 aa)
	rpa3	Replication protein A3. (122 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (391 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (925 aa)
	ENSORLP00000044710	annotation not available (829 aa)
	LOC101156200	Von Willebrand factor A domain containing 5B2. (1400 aa)
	LOC101167715	General transcription factor IIH subunit. (392 aa)
	parp2	Poly [ADP-ribose] polymerase. (649 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000026261	H2M970_ORYLA	ENSORLP00000026261	ENSORLP00000015051	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.838
ENSORLP00000026261	H2MG95_ORYLA	ENSORLP00000026261	ENSORLP00000017626	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.602
ENSORLP00000026261	LOC101154851	ENSORLP00000026261	ENSORLP00000005815	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Cullin 4A; Belongs to the cullin family.	0.482
ENSORLP00000026261	LOC101160651	ENSORLP00000026261	ENSORLP00000026236	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Protein inhibitor of activated STAT, 1b.	0.453
ENSORLP00000026261	LOC101169428	ENSORLP00000026261	ENSORLP00000032876	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Protein inhibitor of activated STAT, 1a.	0.453
ENSORLP00000026261	LOC101169703	ENSORLP00000026261	ENSORLP00000016945	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.744
ENSORLP00000026261	LOC101170318	ENSORLP00000026261	ENSORLP00000036122	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.941
ENSORLP00000026261	RAD23B	ENSORLP00000026261	ENSORLP00000007067	UBIQUITIN_CONJUGAT_2 domain-containing protein.	RAD23 homolog B, nucleotide excision repair protein.	0.684
ENSORLP00000026261	RPA1	ENSORLP00000026261	ENSORLP00000004185	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.493
ENSORLP00000026261	bivm	ENSORLP00000026261	ENSORLP00000019674	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Basic, immunoglobulin-like variable motif containing.	0.510
ENSORLP00000026261	cetn3	ENSORLP00000026261	ENSORLP00000001266	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Centrin 3.	0.542
ENSORLP00000026261	chd1l	ENSORLP00000026261	ENSORLP00000004584	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Chromodomain helicase DNA binding protein 1-like.	0.640
ENSORLP00000026261	cul4b	ENSORLP00000026261	ENSORLP00000001369	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Cullin 4B; Belongs to the cullin family.	0.482
ENSORLP00000026261	ddb1	ENSORLP00000026261	ENSORLP00000001737	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Damage-specific DNA binding protein 1.	0.598
ENSORLP00000026261	ddb2	ENSORLP00000026261	ENSORLP00000008354	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Damage-specific DNA binding protein 2.	0.580
ENSORLP00000026261	ercc2	ENSORLP00000026261	ENSORLP00000032234	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Excision repair cross-complementation group 2.	0.601
ENSORLP00000026261	ercc5	ENSORLP00000026261	ENSORLP00000006287	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Excision repair cross-complementation group 5.	0.510
ENSORLP00000026261	gtf2h5	ENSORLP00000026261	ENSORLP00000026586	UBIQUITIN_CONJUGAT_2 domain-containing protein.	General transcription factor IIH, polypeptide 5.	0.549
ENSORLP00000026261	kctd2	ENSORLP00000026261	ENSORLP00000027547	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.670
ENSORLP00000026261	rad23a	ENSORLP00000026261	ENSORLP00000031881	UBIQUITIN_CONJUGAT_2 domain-containing protein.	RAD23 homolog A, nucleotide excision repair protein a.	0.684