STRINGSTRING
meiob meiob H2LD18_ORYLA H2LD18_ORYLA LOC101155859 LOC101155859 H2L8R4_ORYLA H2L8R4_ORYLA LOC101163644 LOC101163644 aurkb aurkb taf7l taf7l prkaa2 prkaa2 exo1 exo1 rmi1 rmi1 taf10 taf10 LOC101174576 LOC101174576 hipk2 hipk2 rad9b rad9b ENSORLP00000044710 ENSORLP00000044710 LOC101156841 LOC101156841 LOC101159741 LOC101159741 TAF13 TAF13 Rbbp8 Rbbp8 LOC101160001 LOC101160001 prkag1 prkag1 tbpl2 tbpl2 tp53inp1 tp53inp1 ENSORLP00000041460 ENSORLP00000041460 ENSORLP00000041316 ENSORLP00000041316 LOC110014537 LOC110014537 taf2 taf2 ENSORLP00000040118 ENSORLP00000040118 ENSORLP00000039979 ENSORLP00000039979 nuak1 nuak1 hus1 hus1 rpa3 rpa3 rps27a rps27a nuak2 nuak2 rad50 rad50 ENSORLP00000036824 ENSORLP00000036824 kat5 kat5 mdm4 mdm4 rhno1 rhno1 LOC101162042 LOC101162042 ENSORLP00000035200 ENSORLP00000035200 rfc5 rfc5 ENSORLP00000035052 ENSORLP00000035052 taf5l taf5l mdm2 mdm2 tp53inp2 tp53inp2 ssrp1 ssrp1 tdrd3 tdrd3 ENSORLP00000033791 ENSORLP00000033791 ENSORLP00000033770 ENSORLP00000033770 tbpl1 tbpl1 chek2 chek2 LOC101157613 LOC101157613 ENSORLP00000032044 ENSORLP00000032044 ENSORLP00000031002 ENSORLP00000031002 ENSORLP00000030959 ENSORLP00000030959 hipk3 hipk3 ENSORLP00000030413 ENSORLP00000030413 LOC101166457 LOC101166457 recql4 recql4 LOC101160591 LOC101160591 LOC101160131 LOC101160131 cdk2 cdk2 slf1 slf1 ENSORLP00000027619 ENSORLP00000027619 taf12 taf12 blm blm LOC101160731 LOC101160731 ENSORLP00000026983 ENSORLP00000026983 ENSORLP00000026979 ENSORLP00000026979 LOC101167450 LOC101167450 ankrd12 ankrd12 ENSORLP00000026451 ENSORLP00000026451 tp53rk tp53rk Atm Atm rfc4 rfc4 LOC101159571 LOC101159571 ccna2 ccna2 exd2 exd2 LOC101174571 LOC101174571 tpx2 tpx2 rfc2 rfc2 H2MX42_ORYLA H2MX42_ORYLA LOC101155912 LOC101155912 LOC101160204 LOC101160204 cdk5 cdk5 cdca7 cdca7 dyrk2 dyrk2 rad17 rad17 LOC101164719 LOC101164719 LOC101161728 LOC101161728 LOC101166167 LOC101166167 stk11 stk11 LOC101161666 LOC101161666 LOC101165238 LOC101165238 rpa2 rpa2 top3a top3a LOC101155764 LOC101155764 taf11 taf11 LOC101159038 LOC101159038 taf5 taf5 CSNK2A2 CSNK2A2 topbp1 topbp1 LOC101162288 LOC101162288 atr atr cdk5r1 cdk5r1 ubc ubc H2M970_ORYLA H2M970_ORYLA TAF4 TAF4 tbp tbp kxd1 kxd1 dna2 dna2 pin1 pin1 LOC101161903 LOC101161903 LOC101175696 LOC101175696 supt16h supt16h uba52 uba52 taf6 taf6 mre11 mre11 LOC101175345 LOC101175345 LOC101156432 LOC101156432 tp53 tp53 rad1 rad1 chek1 chek1 ankrd11 ankrd11 aurka aurka noc2l noc2l LOC101163796 LOC101163796 rmi2 rmi2 rpa1 rpa1 brca1 brca1 CDCA7L CDCA7L prkag2 prkag2 taf3 taf3 ccna1 ccna1 prkaa1 prkaa1 rfc3 rfc3 mapkapk5 mapkapk5 rad9a rad9a RPA1 RPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
meiobMethionine sulfoxide reductase B1b. (462 aa)
H2LD18_ORYLAUncharacterized protein. (253 aa)
LOC101155859Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
H2L8R4_ORYLATATA-box binding protein associated factor 13. (124 aa)
LOC101163644Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (388 aa)
aurkbProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (362 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
exo1Exonuclease 1. (749 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (648 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
LOC101174576Uncharacterized protein. (272 aa)
hipk2Homeodomain interacting protein kinase 2. (1236 aa)
rad9bRAD9 checkpoint clamp component B. (402 aa)
ENSORLP00000044710annotation not available (829 aa)
LOC101156841Transcription initiation factor TFIID subunit. (1986 aa)
LOC101159741Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (629 aa)
TAF13TATA-box binding protein associated factor 13. (150 aa)
Rbbp8SAE2 domain-containing protein. (78 aa)
LOC101160001ANK_REP_REGION domain-containing protein. (658 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (350 aa)
tbpl2TATA box binding protein like 2. (481 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (291 aa)
ENSORLP00000041460Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)
ENSORLP00000041316Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (261 aa)
LOC110014537Protein kinase domain-containing protein. (419 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1319 aa)
ENSORLP00000040118Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
ENSORLP00000039979Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (650 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (299 aa)
rpa3Replication protein A3. (122 aa)
rps27aRibosomal protein S27a. (195 aa)
nuak2NUAK family, SNF1-like kinase, 2. (615 aa)
rad50RAD50 homolog, double strand break repair protein. (1311 aa)
ENSORLP00000036824Uncharacterized protein. (311 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (580 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (491 aa)
rhno1Si:ch73-352p4.5. (266 aa)
LOC101162042Mitogen-activated protein kinase. (361 aa)
ENSORLP00000035200Protein kinase domain-containing protein. (822 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSORLP00000035052Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)
taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (601 aa)
mdm2MDM2 proto-oncogene. (498 aa)
tp53inp2Uncharacterized protein. (306 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (705 aa)
tdrd3Tudor domain containing 3. (799 aa)
ENSORLP00000033791Protein kinase domain-containing protein. (818 aa)
ENSORLP00000033770Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)
tbpl1TBP-like 1. (187 aa)
chek2Checkpoint kinase 2. (526 aa)
LOC101157613Dual specificity tyrosine phosphorylation regulated kinase 3. (604 aa)
ENSORLP00000032044Reverse transcriptase domain-containing protein. (488 aa)
ENSORLP00000031002Uncharacterized protein. (1062 aa)
ENSORLP00000030959Uncharacterized protein. (229 aa)
hipk3Homeodomain interacting protein kinase 3b. (1401 aa)
ENSORLP00000030413Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
LOC101166457Si:ch211-117c9.1. (649 aa)
recql4RecQ helicase-like 4. (1546 aa)
LOC101160591Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (567 aa)
LOC101160131Uncharacterized protein. (325 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
slf1SMC5-SMC6 complex localization factor 1. (900 aa)
ENSORLP00000027619TAN domain-containing protein. (321 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (131 aa)
blmUncharacterized protein. (1393 aa)
LOC101160731Mitogen-activated protein kinase. (360 aa)
ENSORLP00000026983Protein kinase domain-containing protein. (525 aa)
ENSORLP00000026979Protein kinase domain-containing protein. (854 aa)
LOC101167450TAFH domain-containing protein. (905 aa)
ankrd12Ankyrin repeat domain 12. (1906 aa)
ENSORLP00000026451Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (466 aa)
tp53rkTP53 regulating kinase. (230 aa)
AtmUncharacterized protein. (147 aa)
rfc4Replication factor C (activator 1) 4. (355 aa)
LOC101159571Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (288 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (429 aa)
exd2Exonuclease 3'-5' domain containing 2. (623 aa)
LOC101174571Cyclin-dependent kinase 5 activator. (334 aa)
tpx2TPX2 microtubule nucleation factor. (705 aa)
rfc2Replication factor C (activator 1) 2. (355 aa)
H2MX42_ORYLAZgc:171775. (273 aa)
LOC101155912Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
LOC101160204Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (303 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
cdca7Cell division cycle associated 7a. (391 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (578 aa)
rad17RAD17 checkpoint clamp loader component. (621 aa)
LOC101164719Si:ch211-160o17.4. (1134 aa)
LOC101161728Homeodomain interacting protein kinase 1a. (1111 aa)
LOC101166167AMPKBI domain-containing protein. (268 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
LOC101161666Uncharacterized protein. (436 aa)
LOC101165238Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (265 aa)
rpa2Replication protein A2. (280 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa)
LOC101155764TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (817 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (206 aa)
LOC101159038TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (242 aa)
taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (747 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (359 aa)
topbp1DNA topoisomerase II binding protein 1. (1460 aa)
LOC101162288Protein kinase domain-containing protein. (1360 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2160 aa)
cdk5r1Cyclin-dependent kinase 5 activator. (302 aa)
ubcUbiquitin B. (782 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
TAF4TATA-box binding protein associated factor 4. (956 aa)
tbpUncharacterized protein. (407 aa)
kxd1KxDL motif containing 1. (184 aa)
dna2DNA replication helicase/nuclease 2. (1396 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (156 aa)
LOC101161903Cyclin-dependent kinase 5 activator. (328 aa)
LOC101175696Mitogen-activated protein kinase. (354 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1032 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (694 aa)
LOC101175345Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC101156432Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
rad1RAD1 homolog (S. pombe). (282 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (454 aa)
ankrd11Ankyrin repeat domain 11. (2833 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (439 aa)
noc2lNOC2-like nucleolar associated transcriptional repressor. (745 aa)
LOC101163796Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (342 aa)
rmi2RecQ mediated genome instability 2. (140 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
brca1Uncharacterized protein. (1292 aa)
CDCA7Lzf-4CXXC_R1 domain-containing protein. (414 aa)
prkag2Protein kinase, AMP-activated, gamma 2 non-catalytic subunit a. (341 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (957 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (413 aa)
prkaa1Non-specific serine/threonine protein kinase. (572 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
mapkapk5MAPK activated protein kinase 5. (469 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (388 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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