STRINGSTRING
H4C7 H4C7 ENSORLP00000031006 ENSORLP00000031006 LOC101155571 LOC101155571 orc1 orc1 psmc2 psmc2 ENSORLP00000028480 ENSORLP00000028480 LOC111948194 LOC111948194 psme3 psme3 LOC101172846 LOC101172846 cdc23 cdc23 ENSORLP00000026871 ENSORLP00000026871 ENSORLP00000026648 ENSORLP00000026648 LOC101163693 LOC101163693 psmd8 psmd8 bicra bicra LOC101155571-4 LOC101155571-4 anapc15 anapc15 ENSORLP00000026346 ENSORLP00000026346 kpnb1 kpnb1 H2MZJ4_ORYLA H2MZJ4_ORYLA LOC101174330 LOC101174330 LOC101158678 LOC101158678 psmf1 psmf1 psmc4 psmc4 LOC110016721 LOC110016721 LOC101156678 LOC101156678 mcm3 mcm3 psma5 psma5 anapc7 anapc7 orc5 orc5 psmc1 psmc1 mcm9 mcm9 psmc6 psmc6 FZR1 FZR1 orc3 orc3 psmd3 psmd3 LOC101162259 LOC101162259 Cdc27 Cdc27 psma4 psma4 H2L747_ORYLA H2L747_ORYLA LOC101159638 LOC101159638 H2L743_ORYLA H2L743_ORYLA ENSORLP00000045626 ENSORLP00000045626 psmb8 psmb8 psmd5 psmd5 psmc5 psmc5 psmd9 psmd9 psma2 psma2 psme1 psme1 psmb9 psmb9 psmb9-like psmb9-like H2LR68_ORYLA H2LR68_ORYLA psmd1 psmd1 LOC101154878 LOC101154878 psmd6 psmd6 uba52 uba52 LOC101155046 LOC101155046 anapc16 anapc16 kpna1 kpna1 ube2c ube2c psmd2 psmd2 LOC101173089 LOC101173089 tm7sf3 tm7sf3 psmb2 psmb2 ENSORLP00000043593 ENSORLP00000043593 LOC101174862 LOC101174862 psma3 psma3 psmd7 psmd7 mcm5 mcm5 kxd1 kxd1 psmc3 psmc3 psmb1 psmb1 cdc16 cdc16 mcm6 mcm6 ube2s ube2s orc2 orc2 HIST1H4J HIST1H4J H2M8G3_ORYLA H2M8G3_ORYLA H2M970_ORYLA H2M970_ORYLA ubc ubc gmnn gmnn psme2 psme2 anapc5 anapc5 anapc1 anapc1 psmd14 psmd14 mcm2 mcm2 H2LD49_ORYLA H2LD49_ORYLA anapc10 anapc10 psmd13 psmd13 orc4 orc4 H2L392_ORYLA H2L392_ORYLA LOC101155824 LOC101155824 H3-3B H3-3B LOC101157953 LOC101157953 anapc4 anapc4 mcm7 mcm7 H2L4Z2_ORYLA H2L4Z2_ORYLA H2L4Z9_ORYLA H2L4Z9_ORYLA H2L503_ORYLA H2L503_ORYLA H2L5L2_ORYLA H2L5L2_ORYLA anapc2 anapc2 H2L6K8_ORYLA H2L6K8_ORYLA psma1 psma1 psmb4 psmb4 ENSORLP00000031706 ENSORLP00000031706 H2L736_ORYLA H2L736_ORYLA ENSORLP00000042896 ENSORLP00000042896 kpna6 kpna6 ENSORLP00000042631 ENSORLP00000042631 bicral bicral mcm4 mcm4 ENSORLP00000041905 ENSORLP00000041905 LOC101170644 LOC101170644 LOC101155571-3 LOC101155571-3 LOC101174707 LOC101174707 fam89a fam89a LOC101155824-4 LOC101155824-4 psmb7 psmb7 rps27a rps27a ENSORLP00000038070 ENSORLP00000038070 LOC111949049 LOC111949049 cdc6 cdc6 LOC101155824-3 LOC101155824-3 ENSORLP00000037083 ENSORLP00000037083 mcm8 mcm8 LOC101155824-2 LOC101155824-2 ENSORLP00000035450 ENSORLP00000035450 psmb3 psmb3 cdt1 cdt1 ENSORLP00000035124 ENSORLP00000035124 ENSORLP00000034312 ENSORLP00000034312 psmd10 psmd10 ENSORLP00000033843 ENSORLP00000033843 ENSORLP00000033350 ENSORLP00000033350 psmd12 psmd12 LOC101175183 LOC101175183 LOC101155571-2 LOC101155571-2 anapc11 anapc11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H4C7Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (158 aa)
ENSORLP00000031006Histone H2A; Belongs to the histone H2A family. (146 aa)
LOC101155571Histone H2B; Belongs to the histone H2B family. (124 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (911 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
ENSORLP00000028480Uncharacterized protein. (144 aa)
LOC111948194Proteasome subunit beta. (275 aa)
psme3Proteasome activator subunit 3. (256 aa)
LOC101172846Histone H2A; Belongs to the histone H2A family. (128 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (559 aa)
ENSORLP00000026871Histone H2A; Belongs to the histone H2A family. (131 aa)
ENSORLP00000026648Histone H2A; Belongs to the histone H2A family. (144 aa)
LOC101163693Histone H3.3. (136 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1712 aa)
LOC101155571-4Histone H2B 1/2. (124 aa)
anapc15Anaphase promoting complex subunit 15. (137 aa)
ENSORLP00000026346Histone H2A; Belongs to the histone H2A family. (131 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
H2MZJ4_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (144 aa)
LOC101174330PCI domain-containing protein. (468 aa)
LOC101158678Proteasome subunit beta. (278 aa)
psmf1Uncharacterized protein. (271 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
LOC110016721Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LOC101156678UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
mcm3DNA helicase; Belongs to the MCM family. (817 aa)
psma5Proteasome subunit alpha type. (241 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
orc5Origin recognition complex, subunit 5. (441 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (443 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1116 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (498 aa)
orc3Origin recognition complex, subunit 3. (719 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (516 aa)
LOC101162259Proteasome endopeptidase complex. (320 aa)
Cdc27Cell division cycle 27. (382 aa)
psma4Proteasome subunit alpha type. (261 aa)
H2L747_ORYLAHistone H2A; Belongs to the histone H2A family. (130 aa)
LOC101159638Histone H3; Belongs to the histone H3 family. (136 aa)
H2L743_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
ENSORLP00000045626Histone H2B; Belongs to the histone H2B family. (199 aa)
psmb8Proteasome subunit beta. (275 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (524 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
psma2Proteasome subunit alpha type. (234 aa)
psme1Proteasome activator subunit 1. (250 aa)
psmb9Proteasome subunit beta type-9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity). (216 aa)
psmb9-likeProteasome subunit, beta type 9-like. (217 aa)
H2LR68_ORYLAHistone H2A; Belongs to the histone H2A family. (131 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
LOC101154878Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (191 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC101155046Proteasome subunit alpha type. (246 aa)
anapc16Anaphase promoting complex subunit 16. (83 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
LOC101173089Proteasome 26S subunit, non-ATPase 4b. (376 aa)
tm7sf3Transmembrane 7 superfamily member 3. (565 aa)
psmb2Proteasome subunit beta. (199 aa)
ENSORLP00000043593Histone H2A; Belongs to the histone H2A family. (138 aa)
LOC101174862Fizzy/cell division cycle 20 related 1b. (492 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (324 aa)
mcm5DNA helicase; Belongs to the MCM family. (751 aa)
kxd1KxDL motif containing 1. (184 aa)
psmc3Proteasome 26S subunit ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (237 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (226 aa)
orc2Origin recognition complex, subunit 2. (591 aa)
HIST1H4JHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
H2M8G3_ORYLAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
ubcUbiquitin B. (782 aa)
gmnnUncharacterized protein. (233 aa)
psme2Proteasome activator subunit 2. (241 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
anapc1Anaphase promoting complex subunit 1. (1673 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (325 aa)
mcm2DNA helicase; Belongs to the MCM family. (888 aa)
H2LD49_ORYLAHistone H3; Belongs to the histone H3 family. (134 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (433 aa)
H2L392_ORYLAHistone H2A; Belongs to the histone H2A family. (139 aa)
LOC101155824Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H3-3BHistone H3; Belongs to the histone H3 family. (140 aa)
LOC101157953Proteasome 26S subunit, non-ATPase 4a. (372 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
H2L4Z2_ORYLAHistone H2A; Belongs to the histone H2A family. (139 aa)
H2L4Z9_ORYLAHistone H2A; Belongs to the histone H2A family. (140 aa)
H2L503_ORYLAHistone H3; Belongs to the histone H3 family. (100 aa)
H2L5L2_ORYLAHistone H3; Belongs to the histone H3 family. (125 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (802 aa)
H2L6K8_ORYLAHistone H3; Belongs to the histone H3 family. (107 aa)
psma1Proteasome endopeptidase complex. (238 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
ENSORLP00000031706Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
H2L736_ORYLAHistone H2B; Belongs to the histone H2B family. (132 aa)
ENSORLP00000042896annotation not available (132 aa)
kpna6Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
ENSORLP00000042631Histone H2A; Belongs to the histone H2A family. (135 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (787 aa)
mcm4DNA helicase; Belongs to the MCM family. (835 aa)
ENSORLP00000041905Histone H3; Belongs to the histone H3 family. (101 aa)
LOC101170644H2A histone family, member Va; Belongs to the histone H2A family. (316 aa)
LOC101155571-3Histone H2B 1/2. (124 aa)
LOC101174707Proteasome 26S subunit, non-ATPase 11b. (422 aa)
fam89aFamily with sequence similarity 89 member A. (171 aa)
LOC101155824-4Histone H4. (103 aa)
psmb7Proteasome subunit beta. (286 aa)
rps27aRibosomal protein S27a. (195 aa)
ENSORLP00000038070Zgc:171759; Belongs to the histone H2B family. (207 aa)
LOC111949049Proteasome subunit beta. (276 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (568 aa)
LOC101155824-3Histone H4. (103 aa)
ENSORLP00000037083annotation not available (136 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (846 aa)
LOC101155824-2Histone H4. (103 aa)
ENSORLP00000035450Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
psmb3Proteasome subunit beta 3. (223 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
ENSORLP00000035124Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSORLP00000034312Histone H2A; Belongs to the histone H2A family. (140 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSORLP00000033843annotation not available (136 aa)
ENSORLP00000033350Uncharacterized protein. (150 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (457 aa)
LOC101175183Histone H3.3. (136 aa)
LOC101155571-2Histone H2B 1/2. (124 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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