34 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (334 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (391 aa)
	LOC101170539	Exportin 1 (CRM1 homolog, yeast) b. (1084 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1209 aa)
	LOC101161318	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (544 aa)
	foxm1	Fork-head domain-containing protein. (674 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	ccnb3	Cyclin B3; Belongs to the cyclin family. (425 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (429 aa)
	cdk1	Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II. Catalytic component of MPF (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (303 aa)
	cdc25b	Rhodanese domain-containing protein. (572 aa)
	H2MVE2_ORYLA	Protein phosphatase 4, regulatory subunit 4. (726 aa)
	ppp2r3c	Protein phosphatase 2, regulatory subunit B'', gamma. (448 aa)
	fnbp4	Formin binding protein 4. (843 aa)
	LOC101156733	Wee1-like protein kinase. (569 aa)
	LOC101162061	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (411 aa)
	ccnb1	G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (404 aa)
	LOC101167467	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (445 aa)
	LOC101157461	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
	PPP2R3B	Protein phosphatase 2 regulatory subunit B''beta. (581 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (386 aa)
	LOC101167061	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	ppp4r1	WRNPLPNID domain-containing protein. (969 aa)
	pkmyt1	Protein kinase, membrane associated tyrosine/threonine 1. (568 aa)
	ccna1	Cyclin A1; Belongs to the cyclin family. (413 aa)
	LOC101175126	Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
	wee1	Wee1-like protein kinase. (622 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	ccnb2	G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (387 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	wdr41	WD repeat domain 41. (448 aa)
	ppme1	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (379 aa)
	ppp2r3a	Protein phosphatase 2, regulatory subunit B'', alpha. (1373 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2MVE2_ORYLA	LOC101157461	ENSORLP00000022772	ENSORLP00000015115	Protein phosphatase 4, regulatory subunit 4.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.781
H2MVE2_ORYLA	LOC101161318	ENSORLP00000022772	ENSORLP00000031102	Protein phosphatase 4, regulatory subunit 4.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.781
H2MVE2_ORYLA	LOC101167061	ENSORLP00000022772	ENSORLP00000009339	Protein phosphatase 4, regulatory subunit 4.	Protein phosphatase 2, regulatory subunit A, beta b.	0.453
H2MVE2_ORYLA	LOC101167467	ENSORLP00000022772	ENSORLP00000015391	Protein phosphatase 4, regulatory subunit 4.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.781
H2MVE2_ORYLA	PPP2R3B	ENSORLP00000022772	ENSORLP00000013616	Protein phosphatase 4, regulatory subunit 4.	Protein phosphatase 2 regulatory subunit B''beta.	0.725
H2MVE2_ORYLA	lcmt1	ENSORLP00000022772	ENSORLP00000003832	Protein phosphatase 4, regulatory subunit 4.	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	0.693
H2MVE2_ORYLA	ppme1	ENSORLP00000022772	ENSORLP00000043646	Protein phosphatase 4, regulatory subunit 4.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.829
H2MVE2_ORYLA	ppp2ca	ENSORLP00000022772	ENSORLP00000001162	Protein phosphatase 4, regulatory subunit 4.	Serine/threonine-protein phosphatase.	0.852
H2MVE2_ORYLA	ppp2cb	ENSORLP00000022772	ENSORLP00000027862	Protein phosphatase 4, regulatory subunit 4.	Serine/threonine-protein phosphatase.	0.852
H2MVE2_ORYLA	ppp2r3a	ENSORLP00000022772	ENSORLP00000044211	Protein phosphatase 4, regulatory subunit 4.	Protein phosphatase 2, regulatory subunit B'', alpha.	0.725
H2MVE2_ORYLA	ppp2r3c	ENSORLP00000022772	ENSORLP00000022152	Protein phosphatase 4, regulatory subunit 4.	Protein phosphatase 2, regulatory subunit B'', gamma.	0.671
H2MVE2_ORYLA	ppp4r1	ENSORLP00000022772	ENSORLP00000008550	Protein phosphatase 4, regulatory subunit 4.	WRNPLPNID domain-containing protein.	0.559
LOC101156733	LOC101157461	ENSORLP00000019923	ENSORLP00000015115	Wee1-like protein kinase.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.665
LOC101156733	LOC101161318	ENSORLP00000019923	ENSORLP00000031102	Wee1-like protein kinase.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.665
LOC101156733	LOC101162061	ENSORLP00000019923	ENSORLP00000017732	Wee1-like protein kinase.	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	0.817
LOC101156733	LOC101167467	ENSORLP00000019923	ENSORLP00000015391	Wee1-like protein kinase.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.665
LOC101156733	ccna1	ENSORLP00000019923	ENSORLP00000004833	Wee1-like protein kinase.	Cyclin A1; Belongs to the cyclin family.	0.761
LOC101156733	ccna2	ENSORLP00000019923	ENSORLP00000024918	Wee1-like protein kinase.	Cyclin A2; Belongs to the cyclin family.	0.761
LOC101156733	ccnb1	ENSORLP00000019923	ENSORLP00000017132	Wee1-like protein kinase.	G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily.	0.817
LOC101156733	ccnb2	ENSORLP00000019923	ENSORLP00000000759	Wee1-like protein kinase.	G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily.	0.817