STRINGSTRING
gab2 gab2 pik3r1 pik3r1 LOC101171858 LOC101171858 gfra1 gfra1 grb10 grb10 SHC3 SHC3 SRC SRC LOC101159692 LOC101159692 dok6 dok6 gdnf gdnf LOC101167744 LOC101167744 PIK3CA PIK3CA LOC101168152 LOC101168152 shc1 shc1 LOC101170596 LOC101170596 LOC101155144 LOC101155144 fndc3b fndc3b LOC101166170 LOC101166170 LOC101160964 LOC101160964 grb2 grb2 GRB14 GRB14 H2MSU3_ORYLA H2MSU3_ORYLA irs2 irs2 LOC101171874 LOC101171874 NRTN NRTN PSPN PSPN LOC101167523 LOC101167523 LOC101163728 LOC101163728 prkacb prkacb SHC4 SHC4 ret ret LOC101157651 LOC101157651 plcg1 plcg1 LOC101163742 LOC101163742 LOC101172375 LOC101172375 pik3r3 pik3r3 LOC101174195 LOC101174195 pik3cb pik3cb LOC101174984 LOC101174984 LOC101174926 LOC101174926 LOC101164480 LOC101164480 LOC105354845 LOC105354845 LOC101157091 LOC101157091 fndc3a fndc3a pdlim7 pdlim7 shank3 shank3 gab1 gab1 ENSORLP00000042066 ENSORLP00000042066 LOC101158216 LOC101158216 LOC101173260 LOC101173260 pik3cd pik3cd LOC101162318 LOC101162318 frs2 frs2 LOC101165307 LOC101165307 LOC101170876 LOC101170876
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gab2GRB2-associated binding protein 2. (674 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
LOC101171858GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (490 aa)
gfra1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (466 aa)
grb10Growth factor receptor-bound protein 10b. (577 aa)
SHC3SHC adaptor protein 3. (665 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101159692Uncharacterized protein. (440 aa)
dok6Docking protein 6. (341 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (265 aa)
LOC101167744Uncharacterized protein. (2049 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (449 aa)
LOC101170596Uncharacterized protein. (473 aa)
LOC101155144Uncharacterized protein. (466 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
LOC101166170Growth factor receptor bound protein 7. (562 aa)
LOC101160964Uncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
grb2Growth factor receptor-bound protein 2b. (218 aa)
GRB14Growth factor receptor bound protein 14. (538 aa)
H2MSU3_ORYLAUncharacterized protein. (420 aa)
irs2Insulin receptor substrate 2b. (1081 aa)
LOC101171874GDNF family receptor alpha 4a. (432 aa)
NRTNNeurturin. (212 aa)
PSPNPersephin. (112 aa)
LOC101167523GDNF family receptor alpha 3. (453 aa)
LOC101163728Uncharacterized protein. (409 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
SHC4SHC adaptor protein 4. (534 aa)
retRet proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1144 aa)
LOC101157651Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1127 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
LOC101163742Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
LOC101172375Uncharacterized protein. (1694 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (719 aa)
LOC101174195PDZ and LIM domain 5a. (571 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
LOC101174984Insulin receptor substrate 2a. (1049 aa)
LOC101174926Docking protein 2. (618 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
LOC105354845GDNF family receptor alpha 4b. (428 aa)
LOC101157091PH domain-containing protein. (761 aa)
fndc3aFibronectin type III domain containing 3A. (1244 aa)
pdlim7PDZ and LIM domain 7. (491 aa)
shank3SH3 and multiple ankyrin repeat domains 3a. (1971 aa)
gab1GRB2-associated binding protein 1. (795 aa)
ENSORLP00000042066GDNF family receptor alpha 2b. (428 aa)
LOC101158216PDZ and LIM domain 5b. (609 aa)
LOC101173260Docking protein 1b. (657 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
LOC101162318TGF_BETA_2 domain-containing protein. (298 aa)
frs2Fibroblast growth factor receptor substrate 2b. (526 aa)
LOC101165307SH3 and multiple ankyrin repeat domains 1. (2440 aa)
LOC101170876Uncharacterized protein; Belongs to the protein kinase superfamily. (354 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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