14 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110016423	Uncharacterized protein. (313 aa)
	LOC101167529	RAP1A, member of RAS oncogene family b. (185 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (712 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	rapgef1	Uncharacterized protein. (881 aa)
	LOC101172864	Uncharacterized protein. (255 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1403 aa)
	dock7	Dedicator of cytokinesis 7; Belongs to the DOCK family. (2110 aa)
	LOC101158464	Rap guanine nucleotide exchange factor (GEF) 1b. (1184 aa)
	LOC101157091	PH domain-containing protein. (761 aa)
	gab1	GRB2-associated binding protein 1. (795 aa)
	LOC101171247	RAP1A, member of RAS oncogene family a. (202 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101157091	LOC101158464	ENSORLP00000040455	ENSORLP00000030168	PH domain-containing protein.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.583
LOC101157091	LOC101167529	ENSORLP00000040455	ENSORLP00000007312	PH domain-containing protein.	RAP1A, member of RAS oncogene family b.	0.445
LOC101157091	LOC101171247	ENSORLP00000040455	ENSORLP00000042612	PH domain-containing protein.	RAP1A, member of RAS oncogene family a.	0.445
LOC101157091	LOC101172864	ENSORLP00000040455	ENSORLP00000021855	PH domain-containing protein.	Uncharacterized protein.	0.445
LOC101157091	LOC110016423	ENSORLP00000040455	ENSORLP00000033986	PH domain-containing protein.	Uncharacterized protein.	0.670
LOC101157091	crk	ENSORLP00000040455	ENSORLP00000012262	PH domain-containing protein.	CRK proto-oncogene, adaptor protein.	0.670
LOC101157091	crkl	ENSORLP00000040455	ENSORLP00000013917	PH domain-containing protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.670
LOC101157091	dock7	ENSORLP00000040455	ENSORLP00000028827	PH domain-containing protein.	Dedicator of cytokinesis 7; Belongs to the DOCK family.	0.410
LOC101157091	gab1	ENSORLP00000040455	ENSORLP00000041732	PH domain-containing protein.	GRB2-associated binding protein 1.	0.900
LOC101157091	grb2	ENSORLP00000040455	ENSORLP00000019097	PH domain-containing protein.	Growth factor receptor-bound protein 2b.	0.997
LOC101157091	hgf	ENSORLP00000040455	ENSORLP00000012036	PH domain-containing protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.533
LOC101157091	met	ENSORLP00000040455	ENSORLP00000024532	PH domain-containing protein.	MET proto-oncogene, receptor tyrosine kinase.	0.911
LOC101157091	rapgef1	ENSORLP00000040455	ENSORLP00000020777	PH domain-containing protein.	Uncharacterized protein.	0.583
LOC101158464	LOC101157091	ENSORLP00000030168	ENSORLP00000040455	Rap guanine nucleotide exchange factor (GEF) 1b.	PH domain-containing protein.	0.583
LOC101158464	LOC101167529	ENSORLP00000030168	ENSORLP00000007312	Rap guanine nucleotide exchange factor (GEF) 1b.	RAP1A, member of RAS oncogene family b.	0.662
LOC101158464	LOC101171247	ENSORLP00000030168	ENSORLP00000042612	Rap guanine nucleotide exchange factor (GEF) 1b.	RAP1A, member of RAS oncogene family a.	0.662
LOC101158464	LOC101172864	ENSORLP00000030168	ENSORLP00000021855	Rap guanine nucleotide exchange factor (GEF) 1b.	Uncharacterized protein.	0.662
LOC101158464	LOC110016423	ENSORLP00000030168	ENSORLP00000033986	Rap guanine nucleotide exchange factor (GEF) 1b.	Uncharacterized protein.	0.842
LOC101158464	crk	ENSORLP00000030168	ENSORLP00000012262	Rap guanine nucleotide exchange factor (GEF) 1b.	CRK proto-oncogene, adaptor protein.	0.842
LOC101158464	crkl	ENSORLP00000030168	ENSORLP00000013917	Rap guanine nucleotide exchange factor (GEF) 1b.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.842