10 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSORLP00000032097	Uncharacterized protein. (189 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	ubc	Ubiquitin B. (782 aa)
	ENSORLP00000041845	HECT domain-containing protein. (106 aa)
	LOC101166883	X-linked inhibitor of apoptosis. (408 aa)
	rps27a	Ribosomal protein S27a. (195 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1227 aa)
	Nedd4	Uncharacterized protein. (403 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (415 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000032097	PTEN	ENSORLP00000032097	ENSORLP00000025651	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.528
ENSORLP00000032097	pten	ENSORLP00000032097	ENSORLP00000007832	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.528
ENSORLP00000032097	rps27a	ENSORLP00000032097	ENSORLP00000038189	Uncharacterized protein.	Ribosomal protein S27a.	0.796
ENSORLP00000032097	ubc	ENSORLP00000032097	ENSORLP00000015065	Uncharacterized protein.	Ubiquitin B.	0.781
ENSORLP00000041845	Nedd4	ENSORLP00000041845	ENSORLP00000032640	HECT domain-containing protein.	Uncharacterized protein.	0.899
ENSORLP00000041845	PTEN	ENSORLP00000041845	ENSORLP00000025651	HECT domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.562
ENSORLP00000041845	pten	ENSORLP00000041845	ENSORLP00000007832	HECT domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.562
ENSORLP00000041845	rps27a	ENSORLP00000041845	ENSORLP00000038189	HECT domain-containing protein.	Ribosomal protein S27a.	0.790
ENSORLP00000041845	ubc	ENSORLP00000041845	ENSORLP00000015065	HECT domain-containing protein.	Ubiquitin B.	0.795
LOC101166883	PTEN	ENSORLP00000039982	ENSORLP00000025651	X-linked inhibitor of apoptosis.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.528
LOC101166883	pten	ENSORLP00000039982	ENSORLP00000007832	X-linked inhibitor of apoptosis.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.528
LOC101166883	rps27a	ENSORLP00000039982	ENSORLP00000038189	X-linked inhibitor of apoptosis.	Ribosomal protein S27a.	0.796
LOC101166883	ubc	ENSORLP00000039982	ENSORLP00000015065	X-linked inhibitor of apoptosis.	Ubiquitin B.	0.781
Nedd4	ENSORLP00000041845	ENSORLP00000032640	ENSORLP00000041845	Uncharacterized protein.	HECT domain-containing protein.	0.899
Nedd4	PTEN	ENSORLP00000032640	ENSORLP00000025651	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.562
Nedd4	pten	ENSORLP00000032640	ENSORLP00000007832	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.562
Nedd4	rps27a	ENSORLP00000032640	ENSORLP00000038189	Uncharacterized protein.	Ribosomal protein S27a.	0.790
Nedd4	ubc	ENSORLP00000032640	ENSORLP00000015065	Uncharacterized protein.	Ubiquitin B.	0.795
PTEN	ENSORLP00000032097	ENSORLP00000025651	ENSORLP00000032097	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Uncharacterized protein.	0.528
PTEN	ENSORLP00000041845	ENSORLP00000025651	ENSORLP00000041845	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	HECT domain-containing protein.	0.562