9 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	frs2	Fibroblast growth factor receptor substrate 2b. (526 aa)
	ntrk2	Tyrosine-protein kinase receptor. (745 aa)
	LOC101165978	Uncharacterized protein; Belongs to the DOCK family. (2080 aa)
	ENSORLP00000027787	Neurotrophic tyrosine kinase, receptor, type 2b. (433 aa)
	LOC101157019	Tyrosine-protein kinase. (537 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (281 aa)
	LOC101167011	Tyrosine-protein kinase. (526 aa)
	ENSORLP00000042844	DHR-1 domain-containing protein; Belongs to the DOCK family. (1025 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000027787	bdnf	ENSORLP00000027787	ENSORLP00000031660	Neurotrophic tyrosine kinase, receptor, type 2b.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.896
ENSORLP00000027787	frs2	ENSORLP00000027787	ENSORLP00000044911	Neurotrophic tyrosine kinase, receptor, type 2b.	Fibroblast growth factor receptor substrate 2b.	0.574
ENSORLP00000027787	plcg1	ENSORLP00000027787	ENSORLP00000030443	Neurotrophic tyrosine kinase, receptor, type 2b.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.492
ENSORLP00000042844	LOC101157019	ENSORLP00000042844	ENSORLP00000029844	DHR-1 domain-containing protein; Belongs to the DOCK family.	Tyrosine-protein kinase.	0.422
ENSORLP00000042844	LOC101167011	ENSORLP00000042844	ENSORLP00000041511	DHR-1 domain-containing protein; Belongs to the DOCK family.	Tyrosine-protein kinase.	0.422
ENSORLP00000042844	bdnf	ENSORLP00000042844	ENSORLP00000031660	DHR-1 domain-containing protein; Belongs to the DOCK family.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.557
LOC101157019	ENSORLP00000042844	ENSORLP00000029844	ENSORLP00000042844	Tyrosine-protein kinase.	DHR-1 domain-containing protein; Belongs to the DOCK family.	0.422
LOC101157019	LOC101165978	ENSORLP00000029844	ENSORLP00000012502	Tyrosine-protein kinase.	Uncharacterized protein; Belongs to the DOCK family.	0.422
LOC101157019	LOC101167011	ENSORLP00000029844	ENSORLP00000041511	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC101157019	bdnf	ENSORLP00000029844	ENSORLP00000031660	Tyrosine-protein kinase.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.493
LOC101165978	LOC101157019	ENSORLP00000012502	ENSORLP00000029844	Uncharacterized protein; Belongs to the DOCK family.	Tyrosine-protein kinase.	0.422
LOC101165978	LOC101167011	ENSORLP00000012502	ENSORLP00000041511	Uncharacterized protein; Belongs to the DOCK family.	Tyrosine-protein kinase.	0.422
LOC101165978	bdnf	ENSORLP00000012502	ENSORLP00000031660	Uncharacterized protein; Belongs to the DOCK family.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.557
LOC101167011	ENSORLP00000042844	ENSORLP00000041511	ENSORLP00000042844	Tyrosine-protein kinase.	DHR-1 domain-containing protein; Belongs to the DOCK family.	0.422
LOC101167011	LOC101157019	ENSORLP00000041511	ENSORLP00000029844	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC101167011	LOC101165978	ENSORLP00000041511	ENSORLP00000012502	Tyrosine-protein kinase.	Uncharacterized protein; Belongs to the DOCK family.	0.422
LOC101167011	bdnf	ENSORLP00000041511	ENSORLP00000031660	Tyrosine-protein kinase.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.493
bdnf	ENSORLP00000027787	ENSORLP00000031660	ENSORLP00000027787	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	Neurotrophic tyrosine kinase, receptor, type 2b.	0.896
bdnf	ENSORLP00000042844	ENSORLP00000031660	ENSORLP00000042844	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	DHR-1 domain-containing protein; Belongs to the DOCK family.	0.557
bdnf	LOC101157019	ENSORLP00000031660	ENSORLP00000029844	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	Tyrosine-protein kinase.	0.493