STRINGSTRING
LOC101166777 LOC101166777 LOC101163644 LOC101163644 H2L4B7_ORYLA H2L4B7_ORYLA Mtor Mtor cetn3 cetn3 prkaa2 prkaa2 LOC101155859 LOC101155859 LOC101171417 LOC101171417 LOC101171518 LOC101171518 mlst8 mlst8 H2LEF2_ORYLA H2LEF2_ORYLA LOC101164165 LOC101164165 LOC101161855 LOC101161855 crygn crygn prkaa1 prkaa1 WIPI1 WIPI1 prkag2 prkag2 atg4d atg4d park7 park7 LOC101162462 LOC101162462 becn1 becn1 LOC101163796 LOC101163796 dync1li2 dync1li2 LOC101170291 LOC101170291 lamtor5 lamtor5 arl13b arl13b tm9sf1 tm9sf1 SRC SRC LOC101156432 LOC101156432 LOC101175345 LOC101175345 LOC101164232 LOC101164232 H2LSE1_ORYLA H2LSE1_ORYLA LOC101172193 LOC101172193 LOC101168369 LOC101168369 atg10 atg10 uba52 uba52 LOC101171323 LOC101171323 LOC101162152 LOC101162152 H2M111_ORYLA H2M111_ORYLA txndc11 txndc11 mtmr14 mtmr14 LOC101160205 LOC101160205 kxd1 kxd1 LOC101156446 LOC101156446 ulk1 ulk1 ube2n ube2n atg12 atg12 TSC2 TSC2 fndc3b fndc3b LOC101170049 LOC101170049 H2M970_ORYLA H2M970_ORYLA ubc ubc LOC101169311 LOC101169311 chmp2a chmp2a CSNK2A2 CSNK2A2 uvrag uvrag mterf3 mterf3 LOC101173541 LOC101173541 wdr45b wdr45b LOC101157969 LOC101157969 ILRUN ILRUN wipi2 wipi2 atg9a atg9a tomm40 tomm40 LOC111946865 LOC111946865 fundc1 fundc1 LOC101167046 LOC101167046 chmp7 chmp7 ambra1 ambra1 LOC101158306 LOC101158306 tsc1 tsc1 LOC101165238 LOC101165238 rragc rragc CRYBB3 CRYBB3 LOC101155351 LOC101155351 pgam5 pgam5 LOC101168456 LOC101168456 slc38a9 slc38a9 LOC101163578 LOC101163578 LOC101166167 LOC101166167 atg5 atg5 chmp2b chmp2b chmp3 chmp3 pink1 pink1 LOC101159587 LOC101159587 pofut2 pofut2 LOC101166346 LOC101166346 LOC101168255 LOC101168255 tomm70 tomm70 H2MNV5_ORYLA H2MNV5_ORYLA LOC105354455 LOC105354455 LOC101162245 LOC101162245 LOC101159269 LOC101159269 LOC101155936 LOC101155936 lamtor3 lamtor3 LOC101160204 LOC101160204 LOC101155912 LOC101155912 nbr1 nbr1 lamtor4 lamtor4 atg3 atg3 cftr cftr map1lc3c map1lc3c sqstm1 sqstm1 chmp6 chmp6 atg16l2 atg16l2 c8h17orf75 c8h17orf75 map1lc3a map1lc3a Atm Atm LOC101158600 LOC101158600 pex5 pex5 mfn2 mfn2 LOC101172049 LOC101172049 ENSORLP00000027619 ENSORLP00000027619 wdr45 wdr45 LOC101160591 LOC101160591 pex5l pex5l atg101 atg101 LOC101174042 LOC101174042 rb1cc1 rb1cc1 ENSORLP00000031311 ENSORLP00000031311 TOMM7 TOMM7 rptor rptor vim vim Tsc2 Tsc2 LOC101159112 LOC101159112 atg14 atg14 LOC101155224 LOC101155224 atg13 atg13 chmp4b chmp4b pik3c3 pik3c3 DYNC1I1 DYNC1I1 atg4b atg4b ENSORLP00000036119 ENSORLP00000036119 LOC101170318 LOC101170318 LOC101164480 LOC101164480 LOC101161605 LOC101161605 atg7 atg7 LOC101156643 LOC101156643 ENSORLP00000037597 ENSORLP00000037597 LOC101160603 LOC101160603 rps27a rps27a GABARAPL2 GABARAPL2 LOC101160296 LOC101160296 vdac1 vdac1 map1lc3b map1lc3b usp30 usp30 tomm22 tomm22 fndc3a fndc3a LOC101160680 LOC101160680 tomm5 tomm5 tomm6 tomm6 lamtor2 lamtor2 ift88 ift88 LOC101168810 LOC101168810 gabarap gabarap LOC101166121 LOC101166121 lamtor1 lamtor1 hdac6 hdac6 prkag1 prkag1 LOC101175197 LOC101175197 LOC101173532 LOC101173532 ENSORLP00000043694 ENSORLP00000043694 pik3r4 pik3r4 ENSORLP00000044224 ENSORLP00000044224 LOC101167538 LOC101167538 atg4c atg4c tube1 tube1 dync1i2 dync1i2 mfn1 mfn1 prkn prkn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101166777Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC101163644Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (388 aa)
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
MtorSerine/threonine-protein kinase TOR. (1023 aa)
cetn3Centrin 3. (166 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
LOC101155859Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC101171417Dynein light chain. (89 aa)
LOC101171518Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
H2LEF2_ORYLATubulin domain-containing protein. (136 aa)
LOC101164165Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (496 aa)
LOC101161855Ras homolog, mTORC1 binding. (184 aa)
crygnCrystallin, gamma N2; Belongs to the beta/gamma-crystallin family. (182 aa)
prkaa1Non-specific serine/threonine protein kinase. (572 aa)
WIPI1Uncharacterized protein. (441 aa)
prkag2Protein kinase, AMP-activated, gamma 2 non-catalytic subunit a. (341 aa)
atg4dCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (497 aa)
park7DJ-1. (189 aa)
LOC101162462Dynein light chain. (89 aa)
becn1Beclin 1. (446 aa)
LOC101163796Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (342 aa)
dync1li2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa)
LOC101170291Uncharacterized protein. (331 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
arl13bADP-ribosylation factor-like 13b. (398 aa)
tm9sf1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (594 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101156432Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
LOC101175345Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC101164232Tubulin domain-containing protein. (100 aa)
H2LSE1_ORYLADynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (331 aa)
LOC101172193Peroxisomal biogenesis factor 5-like b. (603 aa)
LOC101168369Charged multivesicular body protein 6a. (208 aa)
atg10ATG10 autophagy related 10 homolog (S. cerevisiae). (256 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC101171323Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (250 aa)
LOC101162152Ras-related GTP binding A. (315 aa)
H2M111_ORYLAUncharacterized protein. (723 aa)
txndc11Thioredoxin domain containing 11. (845 aa)
mtmr14Myotubularin related protein 14. (499 aa)
LOC101160205Zgc:109986. (313 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC101156446Charged multivesicular body protein 4C. (223 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1020 aa)
ube2nUbiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
TSC2TSC complex subunit 2. (1608 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
LOC101170049Zgc:92606. (117 aa)
H2M970_ORYLAUbiquitin-like domain-containing protein. (129 aa)
ubcUbiquitin B. (782 aa)
LOC101169311Translocase of outer mitochondrial membrane 20. (146 aa)
chmp2aCharged multivesicular body protein 2A. (220 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (359 aa)
uvragUV radiation resistance associated gene. (719 aa)
mterf3Mitochondrial transcription termination factor 3. (425 aa)
LOC101173541Uncharacterized protein. (222 aa)
wdr45bWD repeat domain 45B. (344 aa)
LOC101157969Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
wipi2WD repeat domain, phosphoinositide interacting 2. (427 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (850 aa)
tomm40Translocase of outer mitochondrial membrane 40 homolog (yeast). (342 aa)
LOC111946865Pericentrin. (2839 aa)
fundc1Uncharacterized protein. (165 aa)
LOC101167046Unc-51 like autophagy activating kinase 1a. (916 aa)
chmp7Charged multivesicular body protein 7. (420 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1376 aa)
LOC101158306Dynein, cytoplasmic 1, intermediate chain 2b. (632 aa)
tsc1TSC complex subunit 1b. (1198 aa)
LOC101165238Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (265 aa)
rragcRas-related GTP binding Ca. (392 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (237 aa)
LOC101155351Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
pgam5PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (297 aa)
LOC101168456GABA(A) receptor-associated protein like 2. (88 aa)
slc38a9Solute carrier family 38 member 9. (551 aa)
LOC101163578Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (452 aa)
LOC101166167AMPKBI domain-containing protein. (268 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
chmp2bCharged multivesicular body protein 2Bb. (215 aa)
chmp3Charged multivesicular body protein 3. (220 aa)
pink1PTEN induced kinase 1. (577 aa)
LOC101159587Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa)
pofut2Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (481 aa)
LOC101166346Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (413 aa)
LOC101168255Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
tomm70Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (577 aa)
H2MNV5_ORYLATubulin domain-containing protein. (103 aa)
LOC105354455Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (783 aa)
LOC101162245Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
LOC101159269WD repeat domain, phosphoinositide interacting 1. (452 aa)
LOC101155936NBR1 autophagy cargo receptor b. (871 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (132 aa)
LOC101160204Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (303 aa)
LOC101155912Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
nbr1NBR1 autophagy cargo receptor a. (1034 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (101 aa)
atg3Autophagy-related protein 3. (300 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1502 aa)
map1lc3cMicrotubule-associated protein 1 light chain 3 gamma. (128 aa)
sqstm1Sequestosome 1. (436 aa)
chmp6Charged multivesicular body protein 6. (221 aa)
atg16l2WD_REPEATS_REGION domain-containing protein. (616 aa)
c8h17orf75Zgc:153240. (392 aa)
map1lc3aMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)
AtmUncharacterized protein. (147 aa)
LOC101158600Inflammation and lipid regulator with UBA-like and NBR1-like domains. (348 aa)
pex5Peroxisomal biogenesis factor 5. (680 aa)
mfn2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
LOC101172049Translocase of outer mitochondrial membrane 20b. (146 aa)
ENSORLP00000027619TAN domain-containing protein. (321 aa)
wdr45WD repeat domain 45. (358 aa)
LOC101160591Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (567 aa)
pex5lPeroxisomal biogenesis factor 5-like a. (634 aa)
atg101Autophagy related 101. (218 aa)
LOC101174042Dynein light chain. (89 aa)
rb1cc1RB1-inducible coiled-coil 1. (1592 aa)
ENSORLP00000031311Uncharacterized protein. (248 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1372 aa)
vimVimentin like; Belongs to the intermediate filament family. (455 aa)
Tsc2DUF3384 domain-containing protein. (164 aa)
LOC101159112Microtubule-associated protein 1 light chain 3 gamma, like. (136 aa)
atg14Autophagy related 14. (576 aa)
LOC101155224Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (514 aa)
atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (539 aa)
chmp4bCharged multivesicular body protein 4Bb. (251 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (647 aa)
atg4bCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (408 aa)
ENSORLP00000036119Reverse transcriptase domain-containing protein. (1043 aa)
LOC101170318UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
LOC101161605Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (183 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (716 aa)
LOC101156643Ras homolog, mTORC1 binding like 1. (184 aa)
ENSORLP00000037597Tubulin domain-containing protein. (130 aa)
LOC101160603Uncharacterized protein. (184 aa)
rps27aRibosomal protein S27a. (195 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
LOC101160296Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
vdac1Voltage-dependent anion channel 1. (299 aa)
map1lc3bRNA-dependent DNA polymerase. (126 aa)
usp30Ubiquitin carboxyl-terminal hydrolase. (500 aa)
tomm22Translocase of outer mitochondrial membrane 22 homolog (yeast). (135 aa)
fndc3aFibronectin type III domain containing 3A. (1244 aa)
LOC101160680Unc-51 like autophagy activating kinase 2. (1031 aa)
tomm5Translocase of outer mitochondrial membrane 5 homolog (yeast). (115 aa)
tomm6Translocase of outer mitochondrial membrane 6 homolog (yeast). (64 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (190 aa)
ift88Intraflagellar transport 88 homolog. (855 aa)
LOC101168810Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
gabarapGABA(A) receptor-associated protein b. (162 aa)
LOC101166121Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (473 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
hdac6Histone deacetylase 6. (1073 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (350 aa)
LOC101175197Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
LOC101173532FUN14 domain containing 1. (152 aa)
ENSORLP00000043694Tubulin domain-containing protein; Belongs to the tubulin family. (333 aa)
pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1334 aa)
ENSORLP00000044224Fzo_mitofusin domain-containing protein. (297 aa)
LOC101167538Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
atg4cCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (482 aa)
tube1Tubulin, epsilon 1; Belongs to the tubulin family. (472 aa)
dync1i2Dynein, cytoplasmic 1, intermediate chain 2a. (643 aa)
mfn1Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (761 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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