STRINGSTRING
GPX4 GPX4 gpx7 gpx7 esr1 esr1 gapdh gapdh pcna pcna LOC101161140 LOC101161140 gpx8 gpx8 LOC101167730 LOC101167730 LOC111946846 LOC111946846 LOC101161712 LOC101161712 gpx1 gpx1 LOC101174651 LOC101174651 cyp19b cyp19b LOC101161096 LOC101161096 acat2 acat2 LOC101168958 LOC101168958 cyp1a cyp1a gpx3 gpx3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (207 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
LOC101161140Vitellogenin 3, phosvitinless. (1267 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
LOC101167730Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
LOC111946846Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
LOC101161712Cathepsin D. (396 aa)
gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
LOC101174651Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa)
cyp19bAromatase B; Belongs to the cytochrome P450 family. (499 aa)
LOC101161096Glutathione peroxidase; Belongs to the glutathione peroxidase family. (128 aa)
acat2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
LOC101168958Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
cyp1aCytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (521 aa)
gpx3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (173 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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