20 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101161712	Cathepsin D. (396 aa)
	LOC111946846	Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
	LOC101170278	Serine protease; Belongs to the peptidase S1B family. (389 aa)
	c9	Complement component 9. (586 aa)
	ctss	Cathepsin S; Belongs to the peptidase C1 family. (327 aa)
	PRSS23	Serine protease 23. (408 aa)
	mif	Macrophage migration inhibitory factor. (115 aa)
	bf/c2	Bf/C2 protein; Belongs to the peptidase S1 family. (754 aa)
	LOC101165489	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (248 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (590 aa)
	tpi1	Triosephosphate isomerase. (247 aa)
	LOC101168958	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
	tert	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1090 aa)
	LOC101165175	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (339 aa)
	LOC101162015	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (303 aa)
	bcl2	BCL2 apoptosis regulator b. (202 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (316 aa)
	coll	Collagenase. (470 aa)
	LOC101167013	ADAM metallopeptidase with thrombospondin type 1 motif, 3. (1163 aa)
	adam22	ADAM metallopeptidase domain 22. (952 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101161712	LOC101165175	ENSORLP00000000117	ENSORLP00000019706	Cathepsin D.	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	0.662
LOC101161712	ctss	ENSORLP00000000117	ENSORLP00000003921	Cathepsin D.	Cathepsin S; Belongs to the peptidase C1 family.	0.661
LOC101162015	nfkbia	ENSORLP00000019864	ENSORLP00000022136	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.904
LOC101165175	LOC101161712	ENSORLP00000019706	ENSORLP00000000117	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	Cathepsin D.	0.662
LOC101165175	LOC101168958	ENSORLP00000019706	ENSORLP00000016891	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.662
LOC101165175	LOC101170278	ENSORLP00000019706	ENSORLP00000002629	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	Serine protease; Belongs to the peptidase S1B family.	0.402
LOC101165175	LOC111946846	ENSORLP00000019706	ENSORLP00000000114	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	Cathepsin D; Belongs to the peptidase A1 family.	0.673
LOC101165489	tpi1	ENSORLP00000008028	ENSORLP00000015780	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.	Triosephosphate isomerase.	0.901
LOC101167013	c9	ENSORLP00000026973	ENSORLP00000003701	ADAM metallopeptidase with thrombospondin type 1 motif, 3.	Complement component 9.	0.412
LOC101168958	LOC101165175	ENSORLP00000016891	ENSORLP00000019706	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	0.662
LOC101168958	LOC111946846	ENSORLP00000016891	ENSORLP00000000114	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Cathepsin D; Belongs to the peptidase A1 family.	0.901
LOC101168958	ctss	ENSORLP00000016891	ENSORLP00000003921	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.661
LOC101170278	LOC101165175	ENSORLP00000002629	ENSORLP00000019706	Serine protease; Belongs to the peptidase S1B family.	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	0.402
LOC101170278	adam22	ENSORLP00000002629	ENSORLP00000034262	Serine protease; Belongs to the peptidase S1B family.	ADAM metallopeptidase domain 22.	0.510
LOC111946846	LOC101165175	ENSORLP00000000114	ENSORLP00000019706	Cathepsin D; Belongs to the peptidase A1 family.	Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family.	0.673
LOC111946846	LOC101168958	ENSORLP00000000114	ENSORLP00000016891	Cathepsin D; Belongs to the peptidase A1 family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.901
LOC111946846	ctss	ENSORLP00000000114	ENSORLP00000003921	Cathepsin D; Belongs to the peptidase A1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.664
PRSS23	adam22	ENSORLP00000004641	ENSORLP00000034262	Serine protease 23.	ADAM metallopeptidase domain 22.	0.602
adam22	LOC101170278	ENSORLP00000034262	ENSORLP00000002629	ADAM metallopeptidase domain 22.	Serine protease; Belongs to the peptidase S1B family.	0.510
adam22	PRSS23	ENSORLP00000034262	ENSORLP00000004641	ADAM metallopeptidase domain 22.	Serine protease 23.	0.602