31 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
	notch1	Notch receptor 1b. (2507 aa)
	gata2	Transcription factor GATA-2. (455 aa)
	LOC101160196	Ephrin-B3a; Belongs to the ephrin family. (340 aa)
	LOC101164972	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	LOC101158794-2	Homeobox A10b. (320 aa)
	hoxc6	Homeobox C6a. (235 aa)
	hoxc8-2	HoxC8a. (250 aa)
	LOC101174425	Homeobox C5a. (228 aa)
	aldh1a2	Retinaldehyde dehydrogenase type2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	rarb	Retinoic acid receptor beta. (478 aa)
	epha4	Eph receptor A4, like. (990 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	hoxb1	Homeobox B1b. (278 aa)
	LOC101164012	Homeobox B6b. (251 aa)
	cyp26a1	Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (488 aa)
	prdm1	Prdm1a. (845 aa)
	LOC100049436	Her7. (201 aa)
	RARB	Retinoic acid receptor beta. (466 aa)
	LOC101169786	HoxB5a. (311 aa)
	LOC101170520	Homeobox B1a. (394 aa)
	hoxd9	HoxD10a. (336 aa)
	ENSORLP00000027361	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	LOC100125516	Retinoic acid receptor, gamma b. (530 aa)
	actb	Actin, cytoplasmic 1. (434 aa)
	LOC101161908	T-box transcription factor 5a. (525 aa)
	hoxb5	Homeobox B5b. (281 aa)
	LOC101171596	Notch receptor 1a. (2476 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	LOC110015536	Homeobox B3a. (483 aa)
	LOC100049282	Retinoic acid receptor, alpha a. (455 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000027361	LOC101161908	ENSORLP00000027361	ENSORLP00000034931	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	T-box transcription factor 5a.	0.510
ENSORLP00000027361	LOC101164972	ENSORLP00000027361	ENSORLP00000007400	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.467
ENSORLP00000027361	fgf3	ENSORLP00000027361	ENSORLP00000000370	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.562
ENSORLP00000027361	fgf8	ENSORLP00000027361	ENSORLP00000042553	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.543
LOC100049282	cyp26a1	ENSORLP00000045378	ENSORLP00000018194	Retinoic acid receptor, alpha a.	Cytochrome P450 26A1; Belongs to the cytochrome P450 family.	0.479
LOC100049436	LOC101171596	ENSORLP00000020223	ENSORLP00000042502	Her7.	Notch receptor 1a.	0.415
LOC100049436	epha4	ENSORLP00000020223	ENSORLP00000011280	Her7.	Eph receptor A4, like.	0.418
LOC100049436	notch1	ENSORLP00000020223	ENSORLP00000000793	Her7.	Notch receptor 1b.	0.413
LOC101158794-2	LOC101169786	ENSORLP00000009546	ENSORLP00000021319	Homeobox A10b.	HoxB5a.	0.457
LOC101158794-2	hoxb5	ENSORLP00000009546	ENSORLP00000039816	Homeobox A10b.	Homeobox B5b.	0.425
LOC101158794-2	hoxd9	ENSORLP00000009546	ENSORLP00000021943	Homeobox A10b.	HoxD10a.	0.435
LOC101160196	epha4	ENSORLP00000004588	ENSORLP00000011280	Ephrin-B3a; Belongs to the ephrin family.	Eph receptor A4, like.	0.766
LOC101161908	ENSORLP00000027361	ENSORLP00000034931	ENSORLP00000027361	T-box transcription factor 5a.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.510
LOC101161908	LOC101164972	ENSORLP00000034931	ENSORLP00000007400	T-box transcription factor 5a.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.517
LOC101161908	cyp26a1	ENSORLP00000034931	ENSORLP00000018194	T-box transcription factor 5a.	Cytochrome P450 26A1; Belongs to the cytochrome P450 family.	0.451
LOC101164012	LOC101169786	ENSORLP00000015504	ENSORLP00000021319	Homeobox B6b.	HoxB5a.	0.798
LOC101164012	LOC101174425	ENSORLP00000015504	ENSORLP00000009961	Homeobox B6b.	Homeobox C5a.	0.626
LOC101164012	LOC110015536	ENSORLP00000015504	ENSORLP00000044038	Homeobox B6b.	Homeobox B3a.	0.621
LOC101164012	hoxb5	ENSORLP00000015504	ENSORLP00000039816	Homeobox B6b.	Homeobox B5b.	0.802
LOC101164012	hoxc6	ENSORLP00000015504	ENSORLP00000009951	Homeobox B6b.	Homeobox C6a.	0.688