14 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	myog	Myogenin. (248 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
	LOC101161925	Sarcoglycan, alpha. (362 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	sufu	Suppressor of fused homolog. (471 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
	pax7	Uncharacterized protein. (524 aa)
	ahr	Uncharacterized protein. (879 aa)
	LOC101174729	Aryl hydrocarbon receptor 2. (904 aa)
	cdkn1c	Uncharacterized protein. (210 aa)
	LOC101170061	Uncharacterized protein. (866 aa)
	LOC101170311	Uncharacterized protein. (723 aa)
	myf6	Myogenic factor 6. (253 aa)
	mdm2	MDM2 proto-oncogene. (498 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101170061	LOC101170311	ENSORLP00000022790	ENSORLP00000022794	Uncharacterized protein.	Uncharacterized protein.	0.565
LOC101170061	LOC101174729	ENSORLP00000022790	ENSORLP00000000166	Uncharacterized protein.	Aryl hydrocarbon receptor 2.	0.569
LOC101170061	ahr	ENSORLP00000022790	ENSORLP00000000168	Uncharacterized protein.	Uncharacterized protein.	0.575
LOC101170311	LOC101170061	ENSORLP00000022794	ENSORLP00000022790	Uncharacterized protein.	Uncharacterized protein.	0.565
LOC101170311	LOC101174729	ENSORLP00000022794	ENSORLP00000000166	Uncharacterized protein.	Aryl hydrocarbon receptor 2.	0.565
LOC101170311	ahr	ENSORLP00000022794	ENSORLP00000000168	Uncharacterized protein.	Uncharacterized protein.	0.551
LOC101174729	LOC101170061	ENSORLP00000000166	ENSORLP00000022790	Aryl hydrocarbon receptor 2.	Uncharacterized protein.	0.569
LOC101174729	LOC101170311	ENSORLP00000000166	ENSORLP00000022794	Aryl hydrocarbon receptor 2.	Uncharacterized protein.	0.565
LOC101174729	ahr	ENSORLP00000000166	ENSORLP00000000168	Aryl hydrocarbon receptor 2.	Uncharacterized protein.	0.572
ahr	LOC101170061	ENSORLP00000000168	ENSORLP00000022790	Uncharacterized protein.	Uncharacterized protein.	0.575
ahr	LOC101170311	ENSORLP00000000168	ENSORLP00000022794	Uncharacterized protein.	Uncharacterized protein.	0.551
ahr	LOC101174729	ENSORLP00000000168	ENSORLP00000000166	Uncharacterized protein.	Aryl hydrocarbon receptor 2.	0.572
cdkn1c	mdm2	ENSORLP00000038321	ENSORLP00000034706	Uncharacterized protein.	MDM2 proto-oncogene.	0.513
cdkn1c	tp53	ENSORLP00000038321	ENSORLP00000008031	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.702
mdm2	cdkn1c	ENSORLP00000034706	ENSORLP00000038321	MDM2 proto-oncogene.	Uncharacterized protein.	0.513
mdm2	tp53	ENSORLP00000034706	ENSORLP00000008031	MDM2 proto-oncogene.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.999
myf6	myog	ENSORLP00000020357	ENSORLP00000019914	Myogenic factor 6.	Myogenin.	0.662
myf6	pax7	ENSORLP00000020357	ENSORLP00000005345	Myogenic factor 6.	Uncharacterized protein.	0.514
myog	myf6	ENSORLP00000019914	ENSORLP00000020357	Myogenin.	Myogenic factor 6.	0.662
myog	pax7	ENSORLP00000019914	ENSORLP00000005345	Myogenin.	Uncharacterized protein.	0.707