14 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rfx4	Regulatory factor X, 4. (733 aa)
	dync2li1	Dynein, cytoplasmic 2, light intermediate chain 1. (367 aa)
	arl13b	ADP-ribosylation factor-like 13b. (398 aa)
	LOC101162532	Southpaw. (413 aa)
	ift57	Intraflagellar transport 57 homolog (Chlamydomonas). (395 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	pkd1l1	Polycystic kidney disease 1 like 1; Component of a ciliary calcium channel that controls calcium concentration within cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with pkd2l1 in cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and gli2 transcription. Does not constitute the pore-forming subunit (By similarity). Also involved in left/right axis specification downstream of nodal flow: forms a complex with pkd2 in cilia to facilitate flow detection in left/right patterning. (2742 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	foxj1	Fork-head domain-containing protein. (474 aa)
	rfx2	Regulatory factor X, 2 (influences HLA class II expression). (751 aa)
	pitx2	Homeobox protein. (366 aa)
	rfx6	Regulatory factor X, 6. (761 aa)
	foxa2	Hepatocyte nuclear factor 3-beta; Transcription activator for a number of liver genes. Interacts with the cis-acting regulatory regions of these genes (By similarity). (415 aa)
	rfx1	Regulatory factor X, 1b (influences HLA class II expression). (832 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101162532	pitx2	ENSORLP00000008226	ENSORLP00000025501	Southpaw.	Homeobox protein.	0.621
LOC101162532	rfx6	ENSORLP00000008226	ENSORLP00000023283	Southpaw.	Regulatory factor X, 6.	0.439
arl13b	ift57	ENSORLP00000007979	ENSORLP00000008270	ADP-ribosylation factor-like 13b.	Intraflagellar transport 57 homolog (Chlamydomonas).	0.594
arl13b	rfx2	ENSORLP00000007979	ENSORLP00000036414	ADP-ribosylation factor-like 13b.	Regulatory factor X, 2 (influences HLA class II expression).	0.532
arl13b	shh	ENSORLP00000007979	ENSORLP00000013115	ADP-ribosylation factor-like 13b.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.419
dync2li1	ift57	ENSORLP00000005886	ENSORLP00000008270	Dynein, cytoplasmic 2, light intermediate chain 1.	Intraflagellar transport 57 homolog (Chlamydomonas).	0.911
dync2li1	rfx1	ENSORLP00000005886	ENSORLP00000014787	Dynein, cytoplasmic 2, light intermediate chain 1.	Regulatory factor X, 1b (influences HLA class II expression).	0.408
dync2li1	rfx2	ENSORLP00000005886	ENSORLP00000036414	Dynein, cytoplasmic 2, light intermediate chain 1.	Regulatory factor X, 2 (influences HLA class II expression).	0.603
dync2li1	rfx6	ENSORLP00000005886	ENSORLP00000023283	Dynein, cytoplasmic 2, light intermediate chain 1.	Regulatory factor X, 6.	0.509
fgf8	pitx2	ENSORLP00000042553	ENSORLP00000025501	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein.	0.467
fgf8	shh	ENSORLP00000042553	ENSORLP00000013115	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.800
foxa2	shh	ENSORLP00000021768	ENSORLP00000013115	Hepatocyte nuclear factor 3-beta; Transcription activator for a number of liver genes. Interacts with the cis-acting regulatory regions of these genes (By similarity).	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.647
foxj1	rfx2	ENSORLP00000036891	ENSORLP00000036414	Fork-head domain-containing protein.	Regulatory factor X, 2 (influences HLA class II expression).	0.672
ift57	arl13b	ENSORLP00000008270	ENSORLP00000007979	Intraflagellar transport 57 homolog (Chlamydomonas).	ADP-ribosylation factor-like 13b.	0.594
ift57	dync2li1	ENSORLP00000008270	ENSORLP00000005886	Intraflagellar transport 57 homolog (Chlamydomonas).	Dynein, cytoplasmic 2, light intermediate chain 1.	0.911
ift57	rfx1	ENSORLP00000008270	ENSORLP00000014787	Intraflagellar transport 57 homolog (Chlamydomonas).	Regulatory factor X, 1b (influences HLA class II expression).	0.408
ift57	rfx2	ENSORLP00000008270	ENSORLP00000036414	Intraflagellar transport 57 homolog (Chlamydomonas).	Regulatory factor X, 2 (influences HLA class II expression).	0.549
ift57	rfx6	ENSORLP00000008270	ENSORLP00000023283	Intraflagellar transport 57 homolog (Chlamydomonas).	Regulatory factor X, 6.	0.449
pitx2	LOC101162532	ENSORLP00000025501	ENSORLP00000008226	Homeobox protein.	Southpaw.	0.621
pitx2	fgf8	ENSORLP00000025501	ENSORLP00000042553	Homeobox protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467