STRINGSTRING
tgfb3 tgfb3 abcc8 abcc8 smo smo srf srf LOC101172920 LOC101172920 LOC101163302 LOC101163302 pax6 pax6 errb2 errb2 HDAC3 HDAC3 ccnd1 ccnd1 H2L4B7_ORYLA H2L4B7_ORYLA Mtor Mtor LOC101157631 LOC101157631 gli2 gli2 H2L7D8_ORYLA H2L7D8_ORYLA LOC101170159 LOC101170159 LOC101155037 LOC101155037 VANGL2 VANGL2 LOC101156145 LOC101156145 nphp1 nphp1 LOC101163727 LOC101163727 LOC101163727-2 LOC101163727-2 LOC101158706 LOC101158706 klf4 klf4 SRC SRC glis3 glis3 sufu sufu ctbp1 ctbp1 LOC101155815 LOC101155815 glis2 glis2 mycn mycn LOC100125500 LOC100125500 fgf18 fgf18 Tg Tg CUL3 CUL3 LOC101164480 LOC101164480 CPA1 CPA1 mmp14 mmp14 ENSORLP00000032832 ENSORLP00000032832 LOC105358811 LOC105358811 neurod1 neurod1 esrrb esrrb nkx6-1 nkx6-1 LOC101163392 LOC101163392 LOC101163721 LOC101163721 pkd1 pkd1 ccn2 ccn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1565 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
srfSerum response factor b. (611 aa)
LOC101172920CULLIN_2 domain-containing protein; Belongs to the cullin family. (746 aa)
LOC101163302Si:zfos-169g10.2; Belongs to the G-protein coupled receptor 1 family. (481 aa)
pax6Paired box protein Pax-6; May be a transcription factor with important functions in eye and nasal development; Belongs to the paired homeobox family. (457 aa)
errb2Uncharacterized protein. (452 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (440 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
MtorSerine/threonine-protein kinase TOR. (1023 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
gli2GLI family zinc finger 2b. (1358 aa)
H2L7D8_ORYLASomatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (510 aa)
LOC101170159Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
VANGL2Vang-like protein. (525 aa)
LOC101156145Melanin-concentrating hormone receptor 1a. (358 aa)
nphp1Nephronophthisis 1. (532 aa)
LOC101163727Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101163727-2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101158706C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
klf4Kruppel-like factor 4. (425 aa)
SRCTyrosine-protein kinase. (544 aa)
glis3Glis3. (783 aa)
sufuSuppressor of fused homolog. (471 aa)
ctbp1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (443 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
glis2GLIS family zinc finger 2b. (477 aa)
mycnMYCN proto-oncogene, bHLH transcription factor. (451 aa)
LOC100125500Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (430 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
TgCOesterase domain-containing protein. (315 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
CPA1Carboxypeptidase A1. (421 aa)
mmp14ZnMc domain-containing protein. (610 aa)
ENSORLP00000032832BHLH domain-containing protein. (199 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
neurod1Neurogenic differentiation factor. (350 aa)
esrrbUncharacterized protein. (477 aa)
nkx6-1NK6 homeobox 1. (414 aa)
LOC101163392CREB binding protein a. (2409 aa)
LOC101163721Carboxypeptidase A1. (421 aa)
pkd1Uncharacterized protein. (4114 aa)
ccn2Cellular communication network factor 2a. (346 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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