STRINGSTRING
LOC100125474 LOC100125474 LOC101166874 LOC101166874 foxh1 foxh1 cbx2 cbx2 LOC101160347 LOC101160347 wt1-2 wt1-2 ddx46 ddx46 esr1 esr1 fgf20a fgf20a LOC101162674 LOC101162674 actb actb rpl12 rpl12 fgf20b fgf20b dmy dmy foxl2 foxl2 cyp17 cyp17 LOC100049338 LOC100049338 esr2-2 esr2-2 IGFBP3 IGFBP3 SNIP1 SNIP1 RPL5 RPL5 wt1 wt1 nanos3 nanos3 dax1 dax1 LOC101160491 LOC101160491 nanos2 nanos2 LOC101168921 LOC101168921 LOC101160069 LOC101160069 3bhsd 3bhsd dazap1 dazap1 hsd17b8 hsd17b8 fgf16 fgf16 cyp19b cyp19b hsd17b1 hsd17b1 LOC101174651 LOC101174651 arhgap42 arhgap42 cyp17a2 cyp17a2 hsd17b14 hsd17b14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100125474Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (407 aa)
LOC101166874Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (426 aa)
foxh1Forkhead box H1. (511 aa)
cbx2Chromo domain-containing protein. (524 aa)
LOC101160347Ribosomal protein L5. (314 aa)
wt1-2Uncharacterized protein. (418 aa)
ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (1063 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
LOC101162674Insulin-like growth factor binding protein 3. (283 aa)
actbActin, cytoplasmic 1. (434 aa)
rpl12Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (278 aa)
fgf20bFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
dmyDoublesex- and mab-3-related transcription factor 1; Transcription factor that acts both as a transcription. (283 aa)
foxl2Forkhead box L2. (306 aa)
cyp17Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family. (595 aa)
LOC100049338Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (456 aa)
esr2-2Uncharacterized protein. (541 aa)
IGFBP3Insulin like growth factor binding protein 3. (292 aa)
SNIP1Smad nuclear interacting protein 1. (360 aa)
RPL5Ribosomal protein L5b. (280 aa)
wt1Uncharacterized protein. (435 aa)
nanos3NANOS3; Belongs to the nanos family. (201 aa)
dax1NR LBD domain-containing protein. (287 aa)
LOC101160491Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (559 aa)
nanos2Nanos-type domain-containing protein; Belongs to the nanos family. (155 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
LOC101160069Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (448 aa)
3bhsd3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (374 aa)
dazap1DAZ associated protein 1. (435 aa)
hsd17b8Hydroxysteroid (17-beta) dehydrogenase 8. (256 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
cyp19bAromatase B; Belongs to the cytochrome P450 family. (499 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1. (291 aa)
LOC101174651Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa)
arhgap42Rho GTPase activating protein 42b. (899 aa)
cyp17a2Cytochrome P450 family 17 polypeptide 2; Belongs to the cytochrome P450 family. (521 aa)
hsd17b14Hydroxysteroid (17-beta) dehydrogenase 14. (262 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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