STRINGSTRING
LOC101169512 LOC101169512 gpx1 gpx1 LOC101162834 LOC101162834 ddb1 ddb1 LOC101160197 LOC101160197 alx1 alx1 cdc45 cdc45 msh3 msh3 MUTYH MUTYH ercc8 ercc8 LOC101154851 LOC101154851 hnrnpk hnrnpk ung ung neil1 neil1 POLE POLE LOC101171328 LOC101171328 LOC101157282 LOC101157282 PIK3CA PIK3CA LOC101168152 LOC101168152 LOC101161096 LOC101161096 dbf4 dbf4 LOC101174443 LOC101174443 uvssa uvssa mbd4 mbd4 msh6 msh6 pold1 pold1 nthl1 nthl1 GPX4 GPX4 smug1 smug1 hnrnpu hnrnpu neil3 neil3 gpx3 gpx3 cda cda fbxw7 fbxw7 LOC101167466 LOC101167466 gpx8 gpx8 LOC101155571 LOC101155571 ctnnb1 ctnnb1 kras kras LOC101155571-2 LOC101155571-2 LOC101168870 LOC101168870 ccno ccno usp7 usp7 dnmt1 dnmt1 braf braf cdt1 cdt1 sod1 sod1 cdc6 cdc6 pcna pcna prdx5 prdx5 tdg tdg hus1 hus1 LOC101155571-3 LOC101155571-3 abl1 abl1 LOC101156458 LOC101156458 ercc6 ercc6 LOC101155571-4 LOC101155571-4 gpx7 gpx7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101169512Tet methylcytosine dioxygenase 1. (2123 aa)
gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
LOC101162834Thymine DNA glycosylase, tandem duplicate 2. (504 aa)
ddb1Damage-specific DNA binding protein 1. (1126 aa)
LOC101160197E1A binding protein p300 a. (2781 aa)
alx1ALX homeobox 1. (326 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (569 aa)
msh3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1090 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (522 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
LOC101154851Cullin 4A; Belongs to the cullin family. (612 aa)
hnrnpkHeterogeneous nuclear ribonucleoprotein K. (447 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (298 aa)
neil1Nei-like DNA glycosylase 1. (413 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1100 aa)
LOC101171328Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (506 aa)
LOC101157282CCCTC-binding factor (zinc finger protein). (753 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101161096Glutathione peroxidase; Belongs to the glutathione peroxidase family. (128 aa)
dbf4DBF4 zinc finger. (594 aa)
LOC101174443BCR activator of RhoGEF and GTPase. (1421 aa)
uvssaUV-stimulated scaffold protein A. (764 aa)
mbd4Methyl-CpG binding domain protein 4. (440 aa)
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1381 aa)
pold1DNA polymerase. (1107 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (352 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (207 aa)
smug1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (287 aa)
hnrnpuHeterogeneous nuclear ribonucleoprotein Ub. (801 aa)
neil3Nei-like DNA glycosylase 3. (577 aa)
gpx3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (173 aa)
cdaCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (189 aa)
fbxw7F-box and WD repeat domain containing 7. (778 aa)
LOC101167466Heterogeneous nuclear ribonucleoprotein K, like. (498 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
LOC101155571Histone H2B; Belongs to the histone H2B family. (124 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (783 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
LOC101155571-2Histone H2B 1/2. (124 aa)
LOC101168870E1A binding protein p300 b. (2760 aa)
ccnoUncharacterized protein; Belongs to the cyclin family. (400 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1227 aa)
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1496 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (823 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (568 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
prdx5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (189 aa)
tdgThymine DNA glycosylase, tandem duplicate 1. (595 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (299 aa)
LOC101155571-3Histone H2B 1/2. (124 aa)
abl1Tyrosine-protein kinase. (1106 aa)
LOC101156458Apolipoprotein Ba. (4366 aa)
ercc6Excision repair cross-complementation group 6. (1342 aa)
LOC101155571-4Histone H2B 1/2. (124 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.