19 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC101166239	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	CKB	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (407 aa)
	LOC101164721	Creatine kinase, mitochondrial 1A; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
	CKM	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (421 aa)
	CKMT2	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (414 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
	myot	Uncharacterized protein. (984 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	nck1	Cytoplasmic protein. (392 aa)
	pxdn	Peroxidasin. (1481 aa)
	LOC101167262	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	LOC101167730	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	flnc	Uncharacterized protein. (2745 aa)
	actb	Actin, cytoplasmic 1. (434 aa)
	LOC101169907	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (408 aa)
	LOC101173301	Uncharacterized protein. (2544 aa)
	ank2	Ankyrin 2. (1905 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	nck2	Cytoplasmic protein. (398 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKB	LOC101166239	ENSORLP00000000553	ENSORLP00000038248	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	0.488
CKM	LOC101167730	ENSORLP00000001972	ENSORLP00000028200	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.441
LOC101166239	CKB	ENSORLP00000038248	ENSORLP00000000553	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	0.488
LOC101166239	LOC101167262	ENSORLP00000038248	ENSORLP00000025241	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.488
LOC101166239	LOC101167730	ENSORLP00000038248	ENSORLP00000028200	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.441
LOC101166239	LOC101169907	ENSORLP00000038248	ENSORLP00000036138	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.513
LOC101167262	LOC101166239	ENSORLP00000025241	ENSORLP00000038248	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	0.488
LOC101167730	CKM	ENSORLP00000028200	ENSORLP00000001972	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.441
LOC101167730	LOC101166239	ENSORLP00000028200	ENSORLP00000038248	Glyceraldehyde-3-phosphate dehydrogenase.	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	0.441
LOC101167730	LOC101168921	ENSORLP00000028200	ENSORLP00000011676	Glyceraldehyde-3-phosphate dehydrogenase.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.672
LOC101167730	actb	ENSORLP00000028200	ENSORLP00000031145	Glyceraldehyde-3-phosphate dehydrogenase.	Actin, cytoplasmic 1.	0.672
LOC101167730	gapdh	ENSORLP00000028200	ENSORLP00000038395	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.934
LOC101167730	pxdn	ENSORLP00000028200	ENSORLP00000022338	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin.	0.644
LOC101167730	tp53	ENSORLP00000028200	ENSORLP00000008031	Glyceraldehyde-3-phosphate dehydrogenase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.538
LOC101168921	LOC101167730	ENSORLP00000011676	ENSORLP00000028200	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glyceraldehyde-3-phosphate dehydrogenase.	0.672
LOC101168921	gapdh	ENSORLP00000011676	ENSORLP00000038395	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glyceraldehyde-3-phosphate dehydrogenase.	0.841
LOC101168921	nck1	ENSORLP00000011676	ENSORLP00000012449	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytoplasmic protein.	0.419
LOC101168921	nck2	ENSORLP00000011676	ENSORLP00000039494	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytoplasmic protein.	0.419
LOC101168921	pxdn	ENSORLP00000011676	ENSORLP00000022338	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin.	0.572
LOC101168921	tp53	ENSORLP00000011676	ENSORLP00000008031	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.461