STRINGSTRING
e2f1 e2f1 LOC101162450 LOC101162450 LOC101174359 LOC101174359 brca2 brca2 LOC101165351 LOC101165351 LOC101167014 LOC101167014 dmc1 dmc1 rfx2 rfx2 gmnc gmnc trpm7 trpm7 kras kras e2f8 e2f8 actb actb LOC101158338 LOC101158338 scp3 scp3 zmynd10 zmynd10 LOC101164754 LOC101164754 e2f4 e2f4 e2f2 e2f2 LOC101158988 LOC101158988 spo11 spo11 LOC101159189 LOC101159189 LOC101168921 LOC101168921 tp53 tp53 arl13b arl13b sp8 sp8 slc12a1 slc12a1 fancl fancl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
e2f1E2F transcription factor 1. (454 aa)
LOC101162450Notch receptor 3. (2434 aa)
LOC101174359Cor1 domain-containing protein. (214 aa)
brca2BRCA2 DNA repair associated. (3161 aa)
LOC101165351Forkhead box J1b. (446 aa)
LOC101167014Chloride channel K. (676 aa)
dmc1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
rfx2Regulatory factor X, 2 (influences HLA class II expression). (751 aa)
gmncUncharacterized protein. (377 aa)
trpm7Transient receptor potential cation channel, subfamily M, member 7. (1923 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
e2f8E2F transcription factor 8. (908 aa)
actbActin, cytoplasmic 1. (434 aa)
LOC101158338Anion exchange protein. (1126 aa)
scp3Cor1 domain-containing protein. (253 aa)
zmynd10Zinc finger, MYND-type containing 10. (436 aa)
LOC101164754E2F transcription factor 5. (354 aa)
e2f4E2F transcription factor 4. (390 aa)
e2f2Si:ch211-160f23.5. (442 aa)
LOC101158988E2F transcription factor 7. (795 aa)
spo11SPO11 initiator of meiotic double stranded breaks. (399 aa)
LOC101159189Tripartite motif containing 35-30. (257 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
arl13bADP-ribosylation factor-like 13b. (398 aa)
sp8Uncharacterized protein. (458 aa)
slc12a1Solute carrier family 12 member 1. (1048 aa)
fanclFA complementation group L. (377 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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