STRINGSTRING
shh shh wnt3 wnt3 hoxa9 hoxa9 edar edar fgf7 fgf7 ptch1 ptch1 fgf16 fgf16 lef1 lef1 fgf10 fgf10 fgf8 fgf8 fgf20a fgf20a hoxc9 hoxc9 tbx5 tbx5 aldh1a2 aldh1a2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (263 aa)
edarTumor necrosis factor receptor superfamily member EDAR; Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK. (514 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
ptch1Patched 1. (1552 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
lef1Lymphoid enhancer-binding factor 1. (379 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
hoxc9Homeobox protein Hox-C9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (262 aa)
tbx5Uncharacterized protein. (536 aa)
aldh1a2Retinaldehyde dehydrogenase type2; Belongs to the aldehyde dehydrogenase family. (518 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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