STRINGSTRING
drd2 drd2 H2LSA7_ORYLA H2LSA7_ORYLA rbpj rbpj lhx3 lhx3 Nog Nog fgf4 fgf4 H2LGV0_ORYLA H2LGV0_ORYLA yap1 yap1 LOC101162866 LOC101162866 LOC101168366 LOC101168366 gata2 gata2 LOC101174131 LOC101174131 fgf8 fgf8 esr1 esr1 fgf10 fgf10 pitx1 pitx1 lgr5 lgr5 otx2 otx2 wnt3a wnt3a lats2 lats2 egf egf LOC111949309 LOC111949309 ghrh ghrh fshb fshb LOC101172582 LOC101172582 rspo1 rspo1 prrx1 prrx1 prl prl sox1 sox1 shh shh crh crh sox9 sox9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
drd2Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family. (467 aa)
H2LSA7_ORYLANoggin; Belongs to the noggin family. (215 aa)
rbpjRecombination signal binding protein for immunoglobulin kappa J region. (487 aa)
lhx3Uncharacterized protein. (401 aa)
NogNoggin; Belongs to the noggin family. (229 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
H2LGV0_ORYLAANK_REP_REGION domain-containing protein. (740 aa)
yap1Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)
LOC101162866Grainyhead like transcription factor 2. (634 aa)
LOC101168366Keratin 8; Belongs to the intermediate filament family. (530 aa)
gata2Transcription factor GATA-2. (455 aa)
LOC101174131IF rod domain-containing protein; Belongs to the intermediate filament family. (1194 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
pitx1Homeobox protein. (316 aa)
lgr5G_PROTEIN_RECEP_F1_2 domain-containing protein. (909 aa)
otx2Homeobox domain-containing protein. (290 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
lats2Large tumor suppressor kinase 2. (1156 aa)
egfEpidermal growth factor. (966 aa)
LOC111949309HMG box domain-containing protein. (338 aa)
ghrhGrowth hormone releasing hormone. (141 aa)
fshbCys_knot domain-containing protein. (135 aa)
LOC101172582Prolactin. (237 aa)
rspo1Uncharacterized protein. (270 aa)
prrx1Paired related homeobox 1a. (246 aa)
prlProlactin 2. (227 aa)
sox1HMG box domain-containing protein. (322 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
crhCorticotropin-releasing hormone. (163 aa)
sox9HMG box domain-containing protein. (476 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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