STRINGSTRING
cav3 cav3 dab2 dab2 ap2s1 ap2s1 LOC101168921 LOC101168921 LOC101161416 LOC101161416 flot2 flot2 LOC101171789 LOC101171789 LOC101157726 LOC101157726 ap2m1 ap2m1 LOC101171688 LOC101171688 ap2a1 ap2a1 lrp2 lrp2 ldlrap1 ldlrap1 pxdn pxdn cubn cubn ctsl ctsl clta clta actb actb cltc cltc egf egf LOC101161140 LOC101161140 LOC110014685 LOC110014685
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
dab2DAB adaptor protein 2. (761 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
LOC101161416Cathepsin F; Belongs to the peptidase C1 family. (473 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (432 aa)
LOC101171789Cathepsin L.1; Belongs to the peptidase C1 family. (339 aa)
LOC101157726Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (465 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
LOC101171688AP complex subunit beta. (953 aa)
ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (983 aa)
lrp2Low density lipoprotein receptor-related protein 2a. (4493 aa)
ldlrap1Low density lipoprotein receptor adaptor protein 1b. (320 aa)
pxdnPeroxidasin. (1481 aa)
cubnCubilin (intrinsic factor-cobalamin receptor). (3604 aa)
ctslCathepsin L; Belongs to the peptidase C1 family. (336 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
actbActin, cytoplasmic 1. (434 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1695 aa)
egfEpidermal growth factor. (966 aa)
LOC101161140Vitellogenin 3, phosvitinless. (1267 aa)
LOC110014685Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (219 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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