15 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (109 aa)
	LOC100302438	Thrombospondin 1b. (1186 aa)
	thbs1	Uncharacterized protein. (1172 aa)
	vcam1	Vascular cell adhesion molecule 1b. (811 aa)
	LOC101161201	Galectin. (373 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	LOC101172012	Uncharacterized protein. (452 aa)
	ILK	Integrin linked kinase. (452 aa)
	fermt1	Fermitin family member 1. (665 aa)
	LOC101166566	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (281 aa)
	LOC101159552	Galectin. (314 aa)
	itgb4	Integrin beta. (1912 aa)
	itga9	Integrin, alpha 9; Belongs to the integrin alpha chain family. (1029 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cldn5	LOC101166566	ENSORLP00000026956	ENSORLP00000001336	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
ILK	LOC101172012	ENSORLP00000005213	ENSORLP00000005819	Integrin linked kinase.	Uncharacterized protein.	0.900
ILK	fermt1	ENSORLP00000005213	ENSORLP00000035259	Integrin linked kinase.	Fermitin family member 1.	0.791
ILK	itgb4	ENSORLP00000005213	ENSORLP00000043097	Integrin linked kinase.	Integrin beta.	0.726
LOC100302438	itga9	ENSORLP00000022311	ENSORLP00000039434	Thrombospondin 1b.	Integrin, alpha 9; Belongs to the integrin alpha chain family.	0.798
LOC100302438	itgb4	ENSORLP00000022311	ENSORLP00000043097	Thrombospondin 1b.	Integrin beta.	0.739
LOC100302438	thbs1	ENSORLP00000022311	ENSORLP00000021092	Thrombospondin 1b.	Uncharacterized protein.	0.900
LOC101164480	SRC	ENSORLP00000036233	ENSORLP00000008431	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.900
LOC101164480	itga9	ENSORLP00000036233	ENSORLP00000039434	Tyrosine-protein kinase.	Integrin, alpha 9; Belongs to the integrin alpha chain family.	0.722
LOC101164480	itgb4	ENSORLP00000036233	ENSORLP00000043097	Tyrosine-protein kinase.	Integrin beta.	0.936
LOC101166566	Cldn5	ENSORLP00000001336	ENSORLP00000026956	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
LOC101172012	ILK	ENSORLP00000005819	ENSORLP00000005213	Uncharacterized protein.	Integrin linked kinase.	0.900
LOC101172012	fermt1	ENSORLP00000005819	ENSORLP00000035259	Uncharacterized protein.	Fermitin family member 1.	0.791
LOC101172012	itgb4	ENSORLP00000005819	ENSORLP00000043097	Uncharacterized protein.	Integrin beta.	0.726
SRC	LOC101164480	ENSORLP00000008431	ENSORLP00000036233	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.900
SRC	itga9	ENSORLP00000008431	ENSORLP00000039434	Tyrosine-protein kinase.	Integrin, alpha 9; Belongs to the integrin alpha chain family.	0.722
SRC	itgb4	ENSORLP00000008431	ENSORLP00000043097	Tyrosine-protein kinase.	Integrin beta.	0.938
fermt1	ILK	ENSORLP00000035259	ENSORLP00000005213	Fermitin family member 1.	Integrin linked kinase.	0.791
fermt1	LOC101172012	ENSORLP00000035259	ENSORLP00000005819	Fermitin family member 1.	Uncharacterized protein.	0.791
fermt1	itga9	ENSORLP00000035259	ENSORLP00000039434	Fermitin family member 1.	Integrin, alpha 9; Belongs to the integrin alpha chain family.	0.436