STRINGSTRING
LOC101163732 LOC101163732 pofut1 pofut1 LOC101169984 LOC101169984 tp53 tp53 psenen psenen SRC SRC LOC101155616 LOC101155616 hras hras LOC101157726 LOC101157726 egfr egfr spred1 spred1 kras kras sox10 sox10 Col7a1 Col7a1 braf braf oca2 oca2 LOC101164480 LOC101164480 ENSORLP00000039022 ENSORLP00000039022 LOC101160251 LOC101160251
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101163732Microphthalmia-associated transcription factor 2 isoform m. (406 aa)
pofut1Uncharacterized protein. (395 aa)
LOC101169984Receptor protein-tyrosine kinase. (1191 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
psenenPresenilin enhancer, gamma-secretase subunit. (101 aa)
SRCTyrosine-protein kinase. (544 aa)
LOC101155616Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (424 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC101157726Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (465 aa)
egfrReceptor protein-tyrosine kinase. (1185 aa)
spred1Sprouty related EVH1 domain containing 1. (542 aa)
krasGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
sox10SRY-box containing gene 10b. (484 aa)
Col7a1BPTI/Kunitz inhibitor domain-containing protein. (64 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (823 aa)
oca2CitMHS domain-containing protein. (895 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
ENSORLP00000039022Plectin b. (5545 aa)
LOC101160251Plectin a. (4594 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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