12 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	actb	Actin, cytoplasmic 1. (434 aa)
	pgr	Uncharacterized protein. (667 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
	H2L3G9_ORYLA	Cyclin D3; Belongs to the cyclin family. (216 aa)
	ccnd1	Cyclin D1; Belongs to the cyclin family. (292 aa)
	cdk6	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	pxdn	Peroxidasin. (1481 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (429 aa)
	LOC101167730	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2L3G9_ORYLA	cdk2	ENSORLP00000000290	ENSORLP00000028402	Cyclin D3; Belongs to the cyclin family.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.645
H2L3G9_ORYLA	cdk6	ENSORLP00000000290	ENSORLP00000005122	Cyclin D3; Belongs to the cyclin family.	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	0.976
LOC101167730	LOC101168921	ENSORLP00000028200	ENSORLP00000011676	Glyceraldehyde-3-phosphate dehydrogenase.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.672
LOC101167730	actb	ENSORLP00000028200	ENSORLP00000031145	Glyceraldehyde-3-phosphate dehydrogenase.	Actin, cytoplasmic 1.	0.672
LOC101167730	gapdh	ENSORLP00000028200	ENSORLP00000038395	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.934
LOC101167730	pxdn	ENSORLP00000028200	ENSORLP00000022338	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin.	0.644
LOC101168921	LOC101167730	ENSORLP00000011676	ENSORLP00000028200	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glyceraldehyde-3-phosphate dehydrogenase.	0.672
LOC101168921	esr1	ENSORLP00000011676	ENSORLP00000042539	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.501
LOC101168921	gapdh	ENSORLP00000011676	ENSORLP00000038395	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glyceraldehyde-3-phosphate dehydrogenase.	0.841
LOC101168921	pxdn	ENSORLP00000011676	ENSORLP00000022338	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin.	0.572
actb	LOC101167730	ENSORLP00000031145	ENSORLP00000028200	Actin, cytoplasmic 1.	Glyceraldehyde-3-phosphate dehydrogenase.	0.672
actb	esr1	ENSORLP00000031145	ENSORLP00000042539	Actin, cytoplasmic 1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.501
actb	gapdh	ENSORLP00000031145	ENSORLP00000038395	Actin, cytoplasmic 1.	Glyceraldehyde-3-phosphate dehydrogenase.	0.841
actb	pxdn	ENSORLP00000031145	ENSORLP00000022338	Actin, cytoplasmic 1.	Peroxidasin.	0.572
ccna2	cdk2	ENSORLP00000024918	ENSORLP00000028402	Cyclin A2; Belongs to the cyclin family.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.996
ccna2	cdk6	ENSORLP00000024918	ENSORLP00000005122	Cyclin A2; Belongs to the cyclin family.	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	0.933
ccnd1	cdk2	ENSORLP00000000387	ENSORLP00000028402	Cyclin D1; Belongs to the cyclin family.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.909
ccnd1	cdk6	ENSORLP00000000387	ENSORLP00000005122	Cyclin D1; Belongs to the cyclin family.	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	0.995
ccnd1	esr1	ENSORLP00000000387	ENSORLP00000042539	Cyclin D1; Belongs to the cyclin family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.584
cdk2	H2L3G9_ORYLA	ENSORLP00000028402	ENSORLP00000000290	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	Cyclin D3; Belongs to the cyclin family.	0.645