40 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (532 aa)
	dvl1	Dishevelled segment polarity protein 1a. (728 aa)
	tyr	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. (547 aa)
	adcy5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1196 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	bloc1s3	Biogenesis of lysosomal organelles complex-1, subunit 3. (194 aa)
	LOC101157786	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
	LOC101163732	Microphthalmia-associated transcription factor 2 isoform m. (406 aa)
	LOC100125524	Forkhead box N1. (574 aa)
	oca2	CitMHS domain-containing protein. (895 aa)
	sox10	SRY-box containing gene 10b. (484 aa)
	LOC101161292	Tyrosinase-related protein 1b. (540 aa)
	MITF	Melanocyte inducing transcription factor b. (511 aa)
	wnt5b	Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (436 aa)
	actb	Actin, cytoplasmic 1. (434 aa)
	creb3l1	cAMP responsive element binding protein 3-like 1. (505 aa)
	LOC101155960	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa)
	RAB38	RAB38, member RAS oncogene family. (307 aa)
	gpr143	G protein-coupled receptor 143. (436 aa)
	dct	Dopachrome tautomerase. (511 aa)
	wnt9a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
	bcl2	BCL2 apoptosis regulator b. (202 aa)
	pah	Phenylalanine hydroxylase. (506 aa)
	il10	Interleukin 10. (181 aa)
	rab32	RAB32a, member RAS oncogene family. (213 aa)
	ostm1	Osteoclastogenesis associated transmembrane protein 1. (301 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	foxd3	Forkhead box D3. (398 aa)
	BCO2	Beta-carotene oxygenase 2b. (510 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	LOC101160555	Toll-like receptor 9; Belongs to the Toll-like receptor family. (1098 aa)
	rab27a	RAB27A, member RAS oncogene family. (220 aa)
	slc45a2	Uncharacterized protein. (576 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)
	gpnmb	Glycoprotein (transmembrane) nmb. (612 aa)
	TYR	Tyrosinase. (544 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (951 aa)
	tyrp1	Tyrosinase related protein 1. (521 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCO2	gpr143	ENSORLP00000012670	ENSORLP00000022341	Beta-carotene oxygenase 2b.	G protein-coupled receptor 143.	0.521
BCO2	slc45a2	ENSORLP00000012670	ENSORLP00000008198	Beta-carotene oxygenase 2b.	Uncharacterized protein.	0.411
KIF5B	LOC101155960	ENSORLP00000005443	ENSORLP00000002851	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.544
KIF5B	scarb1	ENSORLP00000005443	ENSORLP00000028225	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.556
LOC101155960	KIF5B	ENSORLP00000002851	ENSORLP00000005443	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.544
LOC101155960	scarb1	ENSORLP00000002851	ENSORLP00000028225	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.407
LOC101157786	LOC101163732	ENSORLP00000038119	ENSORLP00000037247	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Microphthalmia-associated transcription factor 2 isoform m.	0.530
LOC101157786	slc45a2	ENSORLP00000038119	ENSORLP00000008198	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein.	0.404
LOC101160555	il10	ENSORLP00000011108	ENSORLP00000019691	Toll-like receptor 9; Belongs to the Toll-like receptor family.	Interleukin 10.	0.543
LOC101161292	LOC101163732	ENSORLP00000033423	ENSORLP00000037247	Tyrosinase-related protein 1b.	Microphthalmia-associated transcription factor 2 isoform m.	0.643
LOC101161292	MITF	ENSORLP00000033423	ENSORLP00000033348	Tyrosinase-related protein 1b.	Melanocyte inducing transcription factor b.	0.619
LOC101161292	TYR	ENSORLP00000033423	ENSORLP00000005706	Tyrosinase-related protein 1b.	Tyrosinase.	0.724
LOC101161292	dct	ENSORLP00000033423	ENSORLP00000022234	Tyrosinase-related protein 1b.	Dopachrome tautomerase.	0.918
LOC101161292	gpr143	ENSORLP00000033423	ENSORLP00000022341	Tyrosinase-related protein 1b.	G protein-coupled receptor 143.	0.677
LOC101161292	oca2	ENSORLP00000033423	ENSORLP00000035151	Tyrosinase-related protein 1b.	CitMHS domain-containing protein.	0.733
LOC101161292	slc45a2	ENSORLP00000033423	ENSORLP00000008198	Tyrosinase-related protein 1b.	Uncharacterized protein.	0.704
LOC101161292	tyrp1	ENSORLP00000033423	ENSORLP00000005420	Tyrosinase-related protein 1b.	Tyrosinase related protein 1.	0.913
LOC101163732	LOC101157786	ENSORLP00000037247	ENSORLP00000038119	Microphthalmia-associated transcription factor 2 isoform m.	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.530
LOC101163732	LOC101161292	ENSORLP00000037247	ENSORLP00000033423	Microphthalmia-associated transcription factor 2 isoform m.	Tyrosinase-related protein 1b.	0.643
LOC101163732	MITF	ENSORLP00000037247	ENSORLP00000033348	Microphthalmia-associated transcription factor 2 isoform m.	Melanocyte inducing transcription factor b.	0.905