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H2L503_ORYLA H2L503_ORYLA hsd17b3 hsd17b3 RPL19 RPL19 ddx4 ddx4 actb actb cyp17 cyp17 gata6 gata6 gata4 gata4 nr5a1 nr5a1 srd5a1 srd5a1 NR5A1 NR5A1 star star H3-2 H3-2 tbp tbp LOC101168921 LOC101168921 3bhsd 3bhsd LOC101170879 LOC101170879 sox9 sox9 H2LD49_ORYLA H2LD49_ORYLA LOC101174651 LOC101174651 LOC101159638 LOC101159638 H2L6K8_ORYLA H2L6K8_ORYLA H2L5L2_ORYLA H2L5L2_ORYLA H2L5K1_ORYLA H2L5K1_ORYLA H3-3B H3-3B LOC101174576 LOC101174576 ENSORLP00000043059 ENSORLP00000043059 ENSORLP00000041905 ENSORLP00000041905
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2L503_ORYLAHistone H3; Belongs to the histone H3 family. (100 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (349 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa)
ddx4Uncharacterized protein; Belongs to the DEAD box helicase family. (727 aa)
actbActin, cytoplasmic 1. (434 aa)
cyp17Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family. (595 aa)
gata6GATA binding protein 6. (489 aa)
gata4GATA binding protein 4. (388 aa)
nr5a1FTZ-F1. (486 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (264 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (453 aa)
starSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
H3-2Histone H3; Belongs to the histone H3 family. (139 aa)
tbpUncharacterized protein. (407 aa)
LOC101168921Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
3bhsd3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (374 aa)
LOC101170879Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (197 aa)
sox9HMG box domain-containing protein. (476 aa)
H2LD49_ORYLAHistone H3; Belongs to the histone H3 family. (134 aa)
LOC101174651Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa)
LOC101159638Histone H3; Belongs to the histone H3 family. (136 aa)
H2L6K8_ORYLAHistone H3; Belongs to the histone H3 family. (107 aa)
H2L5L2_ORYLAHistone H3; Belongs to the histone H3 family. (125 aa)
H2L5K1_ORYLAHistone H3; Belongs to the histone H3 family. (136 aa)
H3-3BHistone H3; Belongs to the histone H3 family. (140 aa)
LOC101174576Uncharacterized protein. (272 aa)
ENSORLP00000043059Histone H3; Belongs to the histone H3 family. (132 aa)
ENSORLP00000041905Histone H3; Belongs to the histone H3 family. (101 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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